3rd Symposium on Infectious Diseases in the Immunocompromised Host

第三届免疫低下宿主传染病研讨会

• 批准号: 9762550
• 负责人: MICHAEL J BOECKH
• 金额: $ 1.8万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-01 至 2020-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762550
• 关键词: Address; Adrenal Cortex Hormones; Adult; Affect; Area; Autoimmune Diseases; Autoimmune Process; Automobile Driving; Biological Response Modifier Therapy; Childhood; Clinical; Clostridium difficile; Communicable Diseases; Country; Cytomegalovirus; Dangerousness; Development; Disease; Elements; Environment; Event; Fostering; Fred Hutchinson Cancer Research Center; General Population; Goals; Immune System Diseases; Immunocompromised Host; Immunotherapy; Individual; Infection; Interdisciplinary Study; Knowledge; Life; Malignant Neoplasms; Mediating; Medical; Medical Students; Mentors; Modality; Morbidity - disease rate; Organ; Patient Care; Patients; Population; Prevention; Primary Infection; Research; Research Personnel; Resources; Savings; Science; Solid; Structure; Talents; Techniques; Time; Training; Training Programs; Training Support; Transplantation; Underrepresented Groups; Underrepresented Minority; United States; United States National Institutes of Health; Virus Diseases; Woman; antimicrobial; cancer therapy; career; clinical practice; experience; hematopoietic cell transplantation; immunosuppressed; improved; improved outcome; infection risk; innovation; interest; lectures; microbiome; mortality; novel; pathogen; pathogenic fungus; patient population; posters; prevent; programs; respiratory virus; response; skills; social group; success; symposium

PROJECT SUMMARY Within the United States, a growing proportion of the population is immunocompromised. Advances in transplantation techniques and cancer treatments, increased survival of these patients, and the development of novel agents to treat autoimmune diseases have contributed to the increase in this population. In the US, it is estimated that more than 340,000 people were living with a functioning transplanted solid organ (SOT) as of 2016, and over 56,000 new hematopoietic cell transplants and SOTs are done every year. Infection remains a major cause of morbidity and mortality for this highly susceptible population. Furthermore, these individuals are often affected by pathogens that rarely cause disease in healthy people. High-quality patient care and fostering collaborative, interdisciplinary research to increase our understanding of these infections, and drive development of new options for treatment and prevention, are vital priorities for improving outcomes among these patients. Conferences focused on infectious diseases specifically within immunocompromised patients are crucial for promoting timely discussions and efficient dissemination of ideas within the field, yet few such forums exist. To bridge this gap, the Fred Hutchinson Cancer Research Center's Infectious Disease Sciences Program launched in 2016 the Symposium on Infectious Diseases in the Immunocompromised Host. This event has attracted high-profile speakers and intense interest among those in the infectious diseases field, allowing us to expand the symposium to a two-day event with 176 attendees in the second year. Our 2019 symposium program will feature lectures by thought leaders in the field as well as early-career investigators, three keynote presentations, two interactive case discussions led by expert panels, and opportunities for trainees including presentations and two poster sessions. New topics addressed in our 2019 symposium program will include: Clostridium difficile, which disproportionately affects immunocompromised patients, and antimicrobial stewardship. Successful elements of our 2017 symposium will be maintained, including coverage of the following topics: Respiratory Virus Disease, Cytomegalovirus, Fungal Disease, Microbiome, and Immunotherapy. A distinct and innovative feature of this event is our focus on supporting attendance and participation by trainees, especially by women and individuals from underrepresented groups. We aim to continue this tradition by providing a generous number of trainee stipends and structuring our program to facilitate meaningful interactions between today's leaders in the field and the rising stars who will contribute to it for decades to come. We aim to foster productive discussions on infectious diseases in the immunocompromised host, driving progress on current issues in the field as well as promoting dissemination of knowledge that will improve clinical practice across the country. This conference strengthens the training pipeline by exposing early-career trainees to this enticing field, while supporting trainees (including those in our NIH-supported T32 training program) in honing their skills and gaining the visibility they need to launch independent careers.

项目摘要 在美国，越来越多的人口免疫功能低下。进展 移植技术和癌症治疗，增加这些患者的生存率，以及 治疗自身免疫性疾病的新药物促进了这一人群的增加。在美国， 据估计，截至2015年，有超过34万人生活在功能正常的移植实体器官（SOT）中。 2016年，每年有超过56，000例新的造血细胞移植和SOT。感染仍然是一个 是这一高度易感人群发病和死亡的主要原因。此外，这些人是 通常受到很少在健康人中引起疾病的病原体的影响。高质量的病人护理和培养 合作，跨学科的研究，以增加我们对这些感染的理解，并推动发展 新的治疗和预防选择是改善这些患者结果的重要优先事项。 会议重点关注传染病，特别是在免疫功能低下的患者是至关重要的， 促进在实地及时讨论和有效传播想法，但这种论坛很少。 为了弥补这一差距，弗雷德哈钦森癌症研究中心的传染病科学计划 2016年，免疫功能低下宿主传染病研讨会（Symposium on Infectious Diseases in the Immunomitted Host）召开。本次活动 吸引了高知名度的演讲者和传染病领域的人们的强烈兴趣，使我们能够 在第二年将研讨会扩大到为期两天的活动，有176人参加。我们的2019年研讨会计划 将由该领域的思想领袖以及早期职业调查人员进行讲座， 专题介绍，由专家小组主持的两次互动式案例讨论，以及为学员提供的机会， 介绍和两个海报会议。我们2019年研讨会计划中讨论的新主题将包括： 艰难梭菌，它不成比例地影响免疫功能低下的患者， 管理工作我们2017年研讨会的成功要素将得到保留，包括以下内容 主题：呼吸道病毒疾病，巨细胞病毒，真菌疾病，微生物组和免疫治疗。 这项活动的一个独特和创新的特点是我们专注于支持学员的出席和参与， 特别是妇女和代表性不足群体的个人。我们的目标是继续这一传统， 提供大量的实习生津贴，并构建我们的计划，以促进有意义的互动 当今该领域的领导者和未来几十年将为之做出贡献的后起之秀之间的关系。我们的目标是 促进关于免疫受损宿主传染病的富有成效的讨论，推动 当前的问题，以及促进知识的传播，将改善临床实践 全国各地本次会议通过让早期职业培训人员了解这一点来加强培训渠道 诱人的领域，同时支持学员（包括那些在我们的NIH支持的T32培训计划）在磨练 他们的技能和获得的知名度，他们需要启动独立的职业生涯。