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Core Facilities for Vision Research

视觉研究核心设施

基本信息

批准号：
9762112
负责人：
MICHAEL E. GOLDBERG
金额：
$ 80万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-08-01 至 2021-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9762112
关键词：
Animals Behavior Biochemical Blindness Brain Clinical Collaborations Communities Computer Hardware Computer software Computers Core Facility Core Grant Custom Data Data Analyses Data Storage and Retrieval Databases Development Disease Drosophila genus Electronics Emergency Situation Equipment Eye Eye Development Fluorescence Microscopy Functional disorder Funding Funding Mechanisms Genetic Genetic study Glaucoma Grant Health Insurance Portability and Accountability Act Histologic Histology Human Image Individual Institutes Laboratories Light Macular degeneration Maintenance Microscopic Microscopy Modification Mus Myopia National Eye Institute Neurosciences Oryctolagus cuniculus Patients Postdoctoral Fellow Privatization Process Qualifying Research Research Personnel Research Project Grants Research Support Resources Retinal Retinal Diseases Rodent Scientist Security Services System Techniques Technology Time Training United States National Institutes of Health Universities Vision Vision research Visual Work base clinical database design fluorescence microscope in vivo in vivo imaging instrument instrumentation light microscopy member microscopic imaging neurophysiology new technology ocular angiogenesis oculomotor behavior programs repaired student training tissue culture tissue preparation vision development vision science visual neuroscience

项目摘要

Project Summary/Abstract Columbia University has a large and vibrant vision research community supported by the National Eye Institute, with 22 qualifying R01 grants and 44 vision scientists in all. Vision research at Columbia ranges across a gamut of topics, from genetic studies of retinal and visual brain development in Drosophila and mice to studies of human retinal disease. Computational, neurophysiological, light microscopic, genetic, biochemical, and clinical techniques focus on a range of problems including the development of the eye and the visual brain, the mechanisms of ocular angiogenesis, the systems neuroscience of visual and oculomotor behavior, and the pathophysiology, genetics, and treatment of retinal diseases such as macular degeneration, myopia, and glaucoma. To support this vision research we are applying to renew our National Eye Institute grant 1P30 EY019007, which will continue to support a set of Core Facilities for Vision Research and enable services that could not be provided by individual research grants. The grant supports three research cores: i) an Instrumentation Fabrication and Design Core that designs and builds custom equipment; ii) a Computer Support Core that performs support and maintenance for the hundreds of computers, including an X-grid cluster and real-time laboratory computer-based interface used by the vision research community; and iii) a Histology and Imaging Core, which provides histological, in vivo, and fluorescent microscopy services. The grant not only supports currently funded investigators with NEI R01s, but also underwrites the work of vision scientists supported by other NEI funding mechanisms, other NIH institutes, and young investigators gathering data in order to submit their first NEI grants. This grant facilitates collaboration among members of the Columbia vision research community, and encourages scientists not currently engaged in vision research to use their expertise in problems related to vision.

项目总结/文摘