Mutant Mouse Resource and Research Center Annual Meeting

突变小鼠资源与研究中心年会

• 批准号: 9890861
• 负责人: Cathleen M Lutz
• 金额: $ 1.16万
• 依托单位: JACKSON LABORATORY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9890861
• 关键词: Advisory Committees; Archives; Atlases; Back; Beta Cell; Biological; Biomedical Research; California; Cellular biology; Collaborations; Collection; Communication; Communities; Complex; Country; Cre driver; Cryopreservation; Data; Defect; Development; Disease susceptibility; ES Cell Line; Electronic Mail; Ensure; Equipment and supply inventories; Ethylnitrosourea; Event; Feedback; Funding; Funding Mechanisms; Gene Expression; Genetic; Genetic Models; Genetically Engineered Mouse; Genomics; Geography; Goals; Growth; Health; Human; Human Resources; Individual; Informatics; Infrastructure; Institution; Knockout Mice; Medicine; Mission; Missouri; Modeling; Mouse Strains; Mus; Mutagenesis; Mutant Strains Mice; Nervous system structure; Neurosciences; North Carolina; Pathway interactions; Performance; Periodicity; Persons; Phase; Pigmentation physiologic function; Principal Investigator; Program Development; Program Reviews; Reproducibility; Request for Proposals; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Series; Services; Standardization; Strategic Planning; TNFSF5 gene; Teleconferences; The Jackson Laboratory; Time; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; Update; comparative; cost; experience; human disease; improved; meetings; member; model development; mouse genetics; mouse model; mutant; operation; parent grant; preservation; programs; public health relevance; repository; response; success; symposium; tool

PROJECT SUMMARY/ABSTRACT The NIH/ORIP/DPCPSI funded, Mutant Mouse Resource and Research Center (MMRRC) is a nation-wide repository of genetically engineered mouse strains created by and for the biomedical research community. The MMRRC was established to ensure the preservation, dissemination, and development of these valuable biological resources and related data. The MMRRC is a consortium of four Centers, each hosting an archive and distribution hub, and an Informatics Coordination and Service Center (ICSC) within a regionally distributed, trans-national network. Daily operations, management and short term strategies are discussed between the Centers and the ICSC by e-mail as well as in monthly consortium-wide teleconferences that involve key personnel and NIH program staff. However, regular in-person meetings are essential for a functional and thriving consortium, especially one that is geographically distributed. Therefore, this proposal seeks support for four, annual in-person meetings of the MMRRC and ICSC principal investigators and key personnel, as well as the four-member, MMRRC External Advisory Committee who will join the meetings biannually. Moreover, these meetings will provide access to directors of other NIH funded resources and an opportunity to showcase the MMRRC to its users – each on a biannual basis. With over 80 years of mouse genetics and repository experience, The Jackson Laboratory joined the MMRRC in 2009 and since has been a key member of the consortium. Moreover, the R13 funding mechanism has supported the annual in-person MMRRC center meetings since the inception of the MMRRC. The Jackson Laboratory is submitting this proposal and will host the parent grant in the event that it is funded; however, each of the four MMRRC centers will have responsibility for organization of one of the four meetings. The overarching goals of these meetings are 1) to provide dedicated time to present center updates and research progress, to articulate new opportunities for collaboration, to evolve long-term program goals / strategies, plan and strategize responses to MMRRC EAC and user feed back and 2) to provide a venue for engagement with external advisors, NIH program officials, MMRRC users and other leaders of the scientific community. !

项目摘要/摘要 NIH/ORIP/DPCPSI资助的突变小鼠资源和研究中心(MMRRC)是一家全国性的 由生物医学研究社区创建的和为生物医学研究社区创建的转基因小鼠品系的储存库。这个 MMRRC的成立是为了确保这些有价值的 生物资源和相关数据。MMRRC是由四个中心组成的联盟，每个中心都有一个档案馆 和分配中心，以及区域分布的信息学协调和服务中心(ICSC)， 跨国网络。讨论日常运营、管理和短期战略 中心和公务员制度委员会通过电子邮件以及每月举行的联合体范围的电话会议，这些会议涉及主要的 人事和NIH项目工作人员。然而，定期的面对面会议对于功能性和 欣欣向荣的财团，尤指地理上分布的财团因此，这项提议寻求支持 四、管理资源和风险管理中心和公务员制度委员会主要调查员和主要人员以及 由四名成员组成的MMRRC外部咨询委员会，每两年参加会议一次。此外， 这些会议将为NIH资助的其他资源的董事提供访问机会，并提供展示 MMRRC向其用户--每个用户每两年一次。拥有80多年的小鼠遗传学和储存库 杰克逊实验室于2009年加入MMRRC，此后一直是MMRRC的关键成员 财团。此外，R13资金机制还支持年度面对面MMRRC中心 自MMRRC成立以来的会议。杰克逊实验室正在提交这项提案，并将主办 在获得资助的情况下，父母提供的赠款；然而，四个MMRRC中心中的每个中心都将拥有 负责组织四次会议中的一次。这些会议的首要目标是1)至 提供专门的时间介绍中心的最新情况和研究进展，阐明新的机会 协作，以制定长期计划目标/战略，规划和制定对MMRRC EAC的响应 和用户反馈，以及2)提供与外部顾问、NIH项目官员、 MMRRC用户和科学界的其他领导人。 好了！