Mutant Mouse Resource and Research Center Annual Meeting

突变小鼠资源与研究中心年会

• 批准号: 9890861
• 负责人: Cathleen M Lutz
• 金额: $ 1.16万
• 依托单位: JACKSON LABORATORY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9890861
• 关键词: Advisory Committees; Archives; Atlases; Back; Beta Cell; Biological; Biomedical Research; California; Cellular biology; Collaborations; Collection; Communication; Communities; Complex; Country; Cre driver; Cryopreservation; Data; Defect; Development; Disease susceptibility; ES Cell Line; Electronic Mail; Ensure; Equipment and supply inventories; Ethylnitrosourea; Event; Feedback; Funding; Funding Mechanisms; Gene Expression; Genetic; Genetic Models; Genetically Engineered Mouse; Genomics; Geography; Goals; Growth; Health; Human; Human Resources; Individual; Informatics; Infrastructure; Institution; Knockout Mice; Medicine; Mission; Missouri; Modeling; Mouse Strains; Mus; Mutagenesis; Mutant Strains Mice; Nervous system structure; Neurosciences; North Carolina; Pathway interactions; Performance; Periodicity; Persons; Phase; Pigmentation physiologic function; Principal Investigator; Program Development; Program Reviews; Reproducibility; Request for Proposals; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Series; Services; Standardization; Strategic Planning; TNFSF5 gene; Teleconferences; The Jackson Laboratory; Time; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; Update; comparative; cost; experience; human disease; improved; meetings; member; model development; mouse genetics; mouse model; mutant; operation; parent grant; preservation; programs; public health relevance; repository; response; success; symposium; tool

PROJECT SUMMARY/ABSTRACT The NIH/ORIP/DPCPSI funded, Mutant Mouse Resource and Research Center (MMRRC) is a nation-wide repository of genetically engineered mouse strains created by and for the biomedical research community. The MMRRC was established to ensure the preservation, dissemination, and development of these valuable biological resources and related data. The MMRRC is a consortium of four Centers, each hosting an archive and distribution hub, and an Informatics Coordination and Service Center (ICSC) within a regionally distributed, trans-national network. Daily operations, management and short term strategies are discussed between the Centers and the ICSC by e-mail as well as in monthly consortium-wide teleconferences that involve key personnel and NIH program staff. However, regular in-person meetings are essential for a functional and thriving consortium, especially one that is geographically distributed. Therefore, this proposal seeks support for four, annual in-person meetings of the MMRRC and ICSC principal investigators and key personnel, as well as the four-member, MMRRC External Advisory Committee who will join the meetings biannually. Moreover, these meetings will provide access to directors of other NIH funded resources and an opportunity to showcase the MMRRC to its users – each on a biannual basis. With over 80 years of mouse genetics and repository experience, The Jackson Laboratory joined the MMRRC in 2009 and since has been a key member of the consortium. Moreover, the R13 funding mechanism has supported the annual in-person MMRRC center meetings since the inception of the MMRRC. The Jackson Laboratory is submitting this proposal and will host the parent grant in the event that it is funded; however, each of the four MMRRC centers will have responsibility for organization of one of the four meetings. The overarching goals of these meetings are 1) to provide dedicated time to present center updates and research progress, to articulate new opportunities for collaboration, to evolve long-term program goals / strategies, plan and strategize responses to MMRRC EAC and user feed back and 2) to provide a venue for engagement with external advisors, NIH program officials, MMRRC users and other leaders of the scientific community. !

项目总结/摘要 NIH/ORIP/DPCPSI资助的突变小鼠资源和研究中心（MMRRC）是一个全国性的 由生物医学研究界创建并为之服务的基因工程小鼠品系库。的 MMRRC的成立是为了确保这些宝贵的保护，传播和发展。 生物资源和相关数据。MMRRC是一个由四个中心组成的联盟，每个中心都有一个档案库 和分发中心，以及一个信息学协调和服务中心（ICSC）， 跨国网络。日常运作，管理和短期战略之间进行了讨论， 通过电子邮件以及每月一次的联合会范围的电话会议， 人员和NIH计划工作人员。然而，定期的面对面会议对于职能和 繁荣的联合体，尤指地理上分散的。因此，本提案寻求支持， 四次，审查、评价和资源中心和国际公务员制度委员会主要调查员和关键人员的年度面对面会议，以及 由四名成员组成的MMRRC外部咨询委员会将每两年参加一次会议。此外，委员会认为， 这些会议将提供机会接触其他NIH资助资源的负责人，并有机会展示 向其用户提供一年两次的小额供资和资源中心。拥有超过80年的小鼠遗传学和储存库 凭借丰富的经验，杰克逊实验室于2009年加入了MMRRC，此后一直是 财团此外，R13供资机制还支持了年度面对面的MMRRC中心 自该委员会成立以来，杰克逊实验室正在提交这一提案，并将主办 在父母补助金的情况下，它是资助;然而，四个MMRRC中心将有 负责组织四次会议之一。这些会议的总体目标是：1） 提供专门的时间来介绍中心的更新和研究进展，阐明新的机会， 协作，制定长期计划目标/战略，计划和战略应对MMRRC EAC 和用户反馈，2）提供一个与外部顾问，NIH项目官员， MMRRC用户和科学界的其他领导人。 !