Rapid initiation of buprenorphine/naloxone to optimize MAT utilization in Philadelphia

快速启动丁丙诺啡/纳洛酮以优化费城 MAT 的利用

基本信息

  • 批准号:
    9896726
  • 负责人:
  • 金额:
    $ 74.62万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-09-30 至 2021-09-29
  • 项目状态:
    已结题

项目摘要

With nearly 10% of the City’s population estimated to have an opioid use disorder and over 1200 overdose deaths recorded in 2017, Philadelphia is an urban epicenter of the opioid epidemic in the United States. The City has the highest rate of opioid overdose deaths of any of the largest cities in the country and there were more than 15,000 overdose responses made by the emergency medical services in 2017. Despite the prevalence of opioid use disorder and broad based support for treatment expansion, approximately 20% of the City’s medication assisted treatment capacity goes unused each year. While this treatment gap is multiply determined, the delays embedded in the typical screening and enrollment process, distance to treatment facilities, and the inherent ambivalence to initiate treatment among opioid dependent individuals, combine to serve as a significant barrier to treatment engagement. The proposed 3-year effort will evaluate a new, mobile strategy for rapid initiation of buprenorphine/naloxone, counseling, peer support and case management as a method for linkage to long term, evidence based medication assisted treatment. Inductions will be initiated in the individual’s home community, either on our mobile medical facility or via home visits. The mobile team will be led by a nurse practitioner (able to prescribe buprenorphine/naloxone in PA) and include a peer recovery specialist, and a case manager. The team will rapidly confirm opioid use disorder, complete informed consent, and begin induction procedures for a “transitional” (one month) course of treatment with buprenorphine/naloxone. During this time, the team will work with the participant to become engaged in existing medication assisted treatment programs. The type of ongoing treatment will be determined on an individual basis and will include options of methadone maintenance, buprenorphine/naloxone treatment, or extended release naltrexone (XR-NTX). Rates of treatment engagement and overdoses at six months will be compared to those participants recruited from the City’s existing assessment and linkage centers. A detailed cost analyses will be conducted to inform future use of this model should it produce positive results. Implementation partners will be Prevention Point Philadelphia and the Public Health Management Corporation. Scientific support will be provided by the University of Pennsylvania Injury Science Center, the Center for Health Economics of Treatment Interventions for Substance Use Disorders, HIV, and HCV and the Center for Studies of Addiction. A Community Advisory Board comprised of consumers, providers and advocates for the health of people with opioid use disorder will help to guide the implementation of the project.
据估计,该市近10%的人口有阿片类药物使用障碍,超过1200人

项目成果

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DAVID S METZGER其他文献

DAVID S METZGER的其他文献

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{{ truncateString('DAVID S METZGER', 18)}}的其他基金

Administrative Core A
行政核心A
  • 批准号:
    10891051
  • 财政年份:
    2023
  • 资助金额:
    $ 74.62万
  • 项目类别:
Effects of mu-opiate receptor engagement on microbial translocation and residual immune activation in HIV-infected, ART suppressed opioid use disorder patents initiating medication-assisted treatment
mu-阿片受体结合对 HIV 感染者、ART 抑制的阿片类药物使用障碍患者微生物易位和残余免疫激活的影响,开始药物辅助治疗
  • 批准号:
    10197865
  • 财政年份:
    2019
  • 资助金额:
    $ 74.62万
  • 项目类别:
Effects of mu-opiate receptor engagement on microbial translocation and residual immune activation in HIV-infected, ART suppressed opioid use disorder patents initiating medication-assisted treatment
mu-阿片受体结合对 HIV 感染者、ART 抑制的阿片类药物使用障碍患者微生物易位和残余免疫激活的影响,开始药物辅助治疗
  • 批准号:
    10436808
  • 财政年份:
    2019
  • 资助金额:
    $ 74.62万
  • 项目类别:
Effects of mu-opiate receptor engagement on microbial translocation and residual immune activation in HIV-infected, ART suppressed opioid use disorder patents initiating medication-assisted treatment
mu-阿片受体结合对 HIV 感染者、ART 抑制的阿片类药物使用障碍患者微生物易位和残余免疫激活的影响,开始药物辅助治疗
  • 批准号:
    10654008
  • 财政年份:
    2019
  • 资助金额:
    $ 74.62万
  • 项目类别:
Effects of mu-opiate receptor engagement on microbial translocation and residual immune activation in HIV-infected, ART suppressed opioid use disorder patents initiating medication-assisted treatment
mu-阿片受体结合对 HIV 感染者、ART 抑制的阿片类药物使用障碍患者微生物易位和残余免疫激活的影响,开始药物辅助治疗
  • 批准号:
    10004224
  • 财政年份:
    2019
  • 资助金额:
    $ 74.62万
  • 项目类别:
Core B: Developmental core
核心B:发展核心
  • 批准号:
    10090663
  • 财政年份:
    2013
  • 资助金额:
    $ 74.62万
  • 项目类别:
Efficacy of Drug-HIV counseling among IDU at Methadone clinics in Jakarta
雅加达美沙酮诊所注射吸毒者药物艾滋病毒咨询的效果
  • 批准号:
    7835556
  • 财政年份:
    2009
  • 资助金额:
    $ 74.62万
  • 项目类别:
Efficacy of Drug-HIV counseling among IDU at Methadone clinics in Jakarta
雅加达美沙酮诊所注射吸毒者药物艾滋病毒咨询的效果
  • 批准号:
    7687184
  • 财政年份:
    2009
  • 资助金额:
    $ 74.62万
  • 项目类别:
Efficacy of Drug-HIV counseling among IDU at Methadone clinics in Jakarta
雅加达美沙酮诊所注射吸毒者药物艾滋病毒咨询的效果
  • 批准号:
    8261981
  • 财政年份:
    2009
  • 资助金额:
    $ 74.62万
  • 项目类别:
Efficacy of Drug-HIV counseling among IDU at Methadone clinics in Jakarta
雅加达美沙酮诊所注射吸毒者药物艾滋病毒咨询的效果
  • 批准号:
    8085908
  • 财政年份:
    2009
  • 资助金额:
    $ 74.62万
  • 项目类别:

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  • 项目类别:
    面上项目

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Building and Implementing Best Practices for Buprenorphine Initiation in the Setting of Fentanyl Use
在芬太尼使用情况下建立和实施丁丙诺啡起始的最佳实践
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    10721763
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    10807173
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    2023
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    $ 74.62万
  • 项目类别:
Beyond Treatment Initiation: Enhancing Opioid Use Disorder Care Transitions Across Health System Touchpoints
除了治疗启动之外:加​​强阿片类药物使用障碍护理在卫生系统接触点的转变
  • 批准号:
    10592062
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    2023
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为寻求阿片类药物使用障碍治疗的人开始微剂量丁丙诺啡
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为寻求阿片类药物使用障碍治疗的人开始微剂量丁丙诺啡
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    10670288
  • 财政年份:
    2022
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Assessing Optimal XR-Buprenorphine Initiation Points in Jail
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阿片类药物的使用对 HIV-1 病毒库动态的影响
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