NARMS surveillance of antibiotic resistance in retail meat in southern California
NARMS 对南加州零售肉类抗生素耐药性的监测
基本信息
- 批准号:9768157
- 负责人:
- 金额:$ 16.6万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-09-01 至 2020-10-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Project Summary/Abstract
Currently there is little data regarding levels of antibiotic resistance for bacteria isolated from
raw meat sold in retail stores from metropolitan Southern California. In order to enhance the
antibiotic resistance surveillance data for the National Antimicrobial Resistance Monitoring
System (NARMS), the Western Institute for Food Safety and Security (WIFSS) and School of
Veterinary Medicine (SVM) at UC Davis propose a collaboration with FDA to survey antibiotic
resistance of bacteria isolated from retail meat in the Greater Los Angeles Area (LA). This
objective will be achieved by undertaking three specific aims. First, retail chicken, ground
turkey, ground beef, and pork chops will be purchased monthly from retail stores in four
geographical regions with different population demographics (East LA, Ontario, West LA,
Irvine). Meat samples will be transported under refrigeration to the UC Davis WIFSS laboratory
where isolation of Salmonella, Campylobacter, E. coli and Enterococcus will be conducted
according to NARMS Retail Meat Surveillance Laboratory Protocol. Confirmed isolates of
Salmonella, Campylobacter, E. coli and Enterococcus will be shipped to FDA-Center for
Veterinary Medicine (CVM) monthly. Second, we will create a database of bacterial antibiotic
resistance in retail meat to better link our results to farm antibiotic resistance surveillance
required by Senate Bill-27 as part of California’s effort to promote prudent antibiotic use and
reduce antibiotic resistance at the farm level. The database will include prevalence of the four
bacteria species for each type of meat, serotypes of Salmonella, patterns of bacterial antibiotic
resistance and sample information (retail location and zip code, source and brand of meat,
processor, packaging, etc.). Linking this new database to NARMS’s existing databases will
expand NARMS’ meat surveillance and facilitate high-dimensional analysis with respect to
tracing foodborne pathogens and antibiotic resistance from farms to retail store outlets. Our third
aim is to enhance collaborations among federal, state and academic stakeholders with respect to
foodborne disease surveillance and outbreak investigation. Collaborating partners in this project
include FDA-CVM, the California Department of Food and Agriculture (CDFA), the California
Department of Public Health (CDPH), and UC Davis WIFSS and SVM. By accomplishing these
specific outcomes the NARMS system will further expand its surveillance of antibiotic resistant
bacteria in retail meat and facilitate collaboration among federal and state agencies and academia
in detection, surveillance, and investigation of foodborne outbreaks associated with antibiotic
resistance.
项目总结/摘要
目前,几乎没有关于从细菌中分离出的细菌的抗生素耐药性水平的数据。
在南加州大都市的零售店出售的生肉。为了增强
国家抗菌药物耐药性监测的抗生素耐药性监测数据
系统(NARMS),西部食品安全和安全研究所(WIFSS)和学校
加州大学戴维斯分校的兽医学(SVM)提议与FDA合作调查抗生素
从大洛杉矶地区(LA)零售肉类中分离出的细菌的耐药性。这
将通过实现三个具体目标来实现这一目标。一、零售鸡、地
火鸡,碎牛肉和猪排将每月从零售店购买,
具有不同人口统计的地理区域(东洛杉矶,安大略,西洛杉矶,
Irvine)。肉类样品将在冷藏条件下运输到加州大学戴维斯分校WIFSS实验室
其中沙门氏菌、弯曲杆菌、E.大肠杆菌和肠球菌将进行
根据NARMS零售肉类监督实验室协议。确认的分离株
沙门氏菌、弯曲杆菌、E.大肠杆菌和肠球菌将被运送到FDA中心,
兽医学(CVM)月刊。其次,我们将建立一个细菌抗生素数据库,
零售肉类的耐药性,以更好地将我们的结果与农场抗生素耐药性监测联系起来
作为加州促进谨慎使用抗生素努力的一部分,
减少农场层面的抗生素耐药性。该数据库将包括四种疾病的患病率,
每种肉类的细菌种类,沙门氏菌的血清型,细菌抗生素的模式
抗性和样品信息(零售地点和邮政编码,肉类的来源和品牌,
处理器、包装等)。将这一新数据库与国家档案管理处现有的数据库连接起来,
扩大NARMS的肉类监测,促进关于以下方面的高维分析:
追踪从农场到零售店的食源性病原体和抗生素耐药性。我们的第三
目的是加强联邦、州和学术界利益相关者之间的合作,
食源性疾病监测和暴发调查。本项目的合作伙伴
包括FDA-CVM、加州食品和农业部(CDFA)、加州
公共卫生部(CDPH),加州大学戴维斯分校WIFSS和SVM。通过实现这些
NARMS系统将进一步扩大对抗生素耐药性的监测,
零售肉类中的细菌,并促进联邦和州机构和学术界之间的合作
在检测、监测和调查与抗生素有关食源性疫情中,
阻力
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Xunde Li', 18)}}的其他基金
Enhancing NARMS surveillance of antibiotic resistance in retail foods in Hawaii
加强夏威夷零售食品中抗生素耐药性的 NARMS 监测
- 批准号:
10169107 - 财政年份:2020
- 资助金额:
$ 16.6万 - 项目类别:
Extending NARMS surveillance of antibiotic resistance in retail foods in California
扩大 NARMS 对加州零售食品抗生素耐药性的监测
- 批准号:
10169108 - 财政年份:2020
- 资助金额:
$ 16.6万 - 项目类别:
Enhancing NARMS surveillance of antibiotic resistance in retail foods in Hawaii
加强夏威夷零售食品中抗生素耐药性的 NARMS 监测
- 批准号:
10247554 - 财政年份:2020
- 资助金额:
$ 16.6万 - 项目类别:
Enhancing NARMS surveillance of antibiotic resistance in retail foods in Hawaii
加强夏威夷零售食品中抗生素耐药性的 NARMS 监测
- 批准号:
10478076 - 财政年份:2020
- 资助金额:
$ 16.6万 - 项目类别:
Extending NARMS surveillance of antibiotic resistance in retail foods in California
扩大 NARMS 对加州零售食品抗生素耐药性的监测
- 批准号:
10478028 - 财政年份:2020
- 资助金额:
$ 16.6万 - 项目类别:
Extending NARMS surveillance of antibiotic resistance in retail foods in California
扩大 NARMS 对加州零售食品抗生素耐药性的监测
- 批准号:
10247558 - 财政年份:2020
- 资助金额:
$ 16.6万 - 项目类别:
NARMS expands surveillance of antimicrobial resistance in retail foods to Hawaii
NARMS 将零售食品中抗菌素耐药性的监测范围扩大到夏威夷
- 批准号:
9920326 - 财政年份:2019
- 资助金额:
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