Tennessee Department of Health: NARMS Cooperative Agreement Program to Enhance and Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens

项目概要/摘要 田纳西州卫生部（TDH）是一个长期的参与者和领导者， NARMS（RFS）计划。TDH认为NARMS的零售食品部门的扩张 是监察食物是否有抗药性的重要一步 和监测最近的国家倡议，包括重要的 在食用动物中使用抗菌剂的监管变化。抗菌药物应用 食用动物生产创造了选择性压力， 细菌进入食物供应并最终导致人类感染。的 值得关注的是，抗生素耐药性感染伴随着更严重的疾病， 死亡，更高的医疗成本和对社会的危害增加。我们觉得 监测是了解AR和多种药物来源的关键“行动数据” 因此，我们需要加强食品供应链中的耐药性（MDR），并应对这一公共卫生问题。 田纳西州接受NARMS食品监督计划的目标，以改善 零售生肉中肠源性细菌AR的检测与监测 通过本合作资助协议（FOA # PAR-16-099，CFDA # 93.876）。田纳西州将全面参与所有项目组成部分，包括购买 批准的肉类，通过NARMS方案进行检测，运输分离株和Meta数据，以及 继续在NARMS工作组开展活动。此外，田纳西州预计， 参与任何未来的试点活动或扩展到其他肉类或商品。 田纳西州检测肉类的能力已经转化为评估 分离株及其与人类集群的联系，以及对肉类检测的更熟练程度 在疫情爆发期间，快速描述AR特性，以告知公众健康 调查田纳西州将充分参与所有NARMS RFS活动，并遵循 在5年期间接受的协议。我们的策略包括：1.保持采样 并在RFS中采用持续质量改进范式进行报告。2.福斯特 田纳西州、联邦、州、地方和外部合作伙伴之间的伙伴关系。3.增强 疫情调查反应和报告。4.维持和加强国家武器装备管理系统 实验室诊断能力。6.改善实验室协调、外联和 信息流7.维护和交流综合监测信息系统。 田纳西州的期望和成果，战略和活动，以及合作 活动将在整个五年期间继续进行，并继续提供资金。

Project Summary/Abstract The Tennessee Department of Health (TDH) is a long-term participant and leader in the NARMS (RFS) program. TDH feels that the expansion of the retail food arm of NARMS is critical step in conducting surveillance for antimicrobial resistance (AR) in the food chain and for monitoring the impact of recent national initiatives including important regulatory changes in the use of antimicrobials in food animals. Use of antimicrobials in food animal production creates selective pressure that enables antimicrobial resistant bacteria to matriculate into the food supply and ultimately cause human infections. Of concern, antibiotic resistant infections are accompanied by more severe illnesses, more deaths, higher healthcare costs, and increased harm to society. We feel that surveillance is critical “data-for-action” to understand the sources of AR and multi-drug resistance (MDR) in the food supply chain and to combat this public health problem. Tennessee embraces the goal of the NARMS food surveillance program to improve the detection of and surveillance for AR among enteric bacteria in raw retail meat commodities through this cooperative funding agreement (FOA # PAR-16-099, CFDA # 93.876). Tennessee will participate fully in all project components including purchase of approved meats, testing by NARMS protocols, shipment of isolates and meta data, and continued activity in the NARMS working group. Additionally, Tennessee anticipates participating in any future pilot activity or expansion to other meats or commodities. Tennessee capacity for testing meats has translated to increased ability to assess isolates and their link to human clusters, as well as more proficiency in testing meats during outbreaks and quickly characterizing the AR properties to inform the public heath investigation. Tennessee will participate fully in all NARMS RFS activities and follow the accepted protocols during the 5 year period. Our strategy include: 1. Maintain sampling and reporting with a continuous quality improvement paradigm in RFS. 2. Foster partnership among Tennessee, federal, state, local, and external partners. 3. Enhance outbreak investigation response and reporting. 4. Sustain and enhance NARMS laboratory diagnostic capacity. 6.Improve laboratory coordination, outreach, and information flow. 7. Maintain and exchange integrated surveillance information system. Tennessee's expectations and outcomes, strategies and activities, and collaborative activities will continue throughout the 5 year period with continued funding.