Tennessee Department of Health: NARMS Cooperative Agreement Program to Enhance and Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens

项目摘要/摘要 田纳西州卫生部是该项目的长期参与者和领导者。 NARMS(RFS)计划。TDH认为，NARMS零售食品部门的扩张 是监测食物中抗菌素耐药性的关键步骤 并监测最近的国家倡议的影响，包括重要的 在食用动物中使用抗菌剂的监管变化。抗菌药物在中国的使用 食用动物生产造成选择性压力，使抗菌素产生抗药性 细菌进入食物供应，最终导致人类感染。的 令人担忧的是，抗生素耐药性感染伴随着更严重的疾病，更多 死亡、更高的医疗成本和更大的社会危害性。我们觉得 监测对于了解AR和多种药物的来源至关重要 消除食品供应链中的耐药性(MDR)，并与这一公共卫生问题作斗争。 田纳西州支持NARMS食品监测计划的目标，以改善 零售生肉中肠道细菌AR的检测与监测 通过该合作筹资协议购买商品(FOA#PAR-16-099，CFDA#年 93.876)。田纳西州将全面参与所有项目组成部分，包括购买 批准的肉类，NARMS协议的测试，分离物和元数据的运输，以及 继续在NARMS工作组开展活动。此外，田纳西州预计 参与任何未来的试点活动或扩展到其他肉类或商品。 田纳西州检测肉类的能力已经转化为评估能力的提高 分离物及其与人类聚集物的联系，以及更熟练地检测肉类 在疫情爆发期间，并快速确定AR属性的特征，以告知公众健康 调查。田纳西州将全面参与NARMS RFS的所有活动，并遵循 在5年内接受的协议。我们的策略包括：1.保持抽样 并在RFS中以持续质量改进范例进行报告。2.寄养家庭 田纳西州、联邦、州、地方和外部合作伙伴之间的伙伴关系。3.增强 疫情调查、应对和报告。4.支持和加强NARMS 实验室诊断能力。6.改善实验室协调、外联和 信息流。7.维护和交换综合监控信息系统。 田纳西州的期望和结果、战略和活动以及协作 在继续提供资金的情况下，活动将在整个5年期间继续进行。

Project Summary/Abstract The Tennessee Department of Health (TDH) is a long-term participant and leader in the NARMS (RFS) program. TDH feels that the expansion of the retail food arm of NARMS is critical step in conducting surveillance for antimicrobial resistance (AR) in the food chain and for monitoring the impact of recent national initiatives including important regulatory changes in the use of antimicrobials in food animals. Use of antimicrobials in food animal production creates selective pressure that enables antimicrobial resistant bacteria to matriculate into the food supply and ultimately cause human infections. Of concern, antibiotic resistant infections are accompanied by more severe illnesses, more deaths, higher healthcare costs, and increased harm to society. We feel that surveillance is critical “data-for-action” to understand the sources of AR and multi-drug resistance (MDR) in the food supply chain and to combat this public health problem. Tennessee embraces the goal of the NARMS food surveillance program to improve the detection of and surveillance for AR among enteric bacteria in raw retail meat commodities through this cooperative funding agreement (FOA # PAR-16-099, CFDA # 93.876). Tennessee will participate fully in all project components including purchase of approved meats, testing by NARMS protocols, shipment of isolates and meta data, and continued activity in the NARMS working group. Additionally, Tennessee anticipates participating in any future pilot activity or expansion to other meats or commodities. Tennessee capacity for testing meats has translated to increased ability to assess isolates and their link to human clusters, as well as more proficiency in testing meats during outbreaks and quickly characterizing the AR properties to inform the public heath investigation. Tennessee will participate fully in all NARMS RFS activities and follow the accepted protocols during the 5 year period. Our strategy include: 1. Maintain sampling and reporting with a continuous quality improvement paradigm in RFS. 2. Foster partnership among Tennessee, federal, state, local, and external partners. 3. Enhance outbreak investigation response and reporting. 4. Sustain and enhance NARMS laboratory diagnostic capacity. 6.Improve laboratory coordination, outreach, and information flow. 7. Maintain and exchange integrated surveillance information system. Tennessee's expectations and outcomes, strategies and activities, and collaborative activities will continue throughout the 5 year period with continued funding.