Tennessee Department of Health: NARMS Cooperative Agreement Program to Enhance and Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens

田纳西州卫生部：NARMS 合作协议计划旨在加强零售食品样本中的抗生素耐药性监测

• 批准号: 9768188
• 负责人: JOHN ROBERT DUNN
• 金额: $ 14.42万
• 依托单位: TENNESSEE STATE DEPARTMENT OF HEALTH
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9768188
• 关键词: Tennessee; Department; Health; NARMS; Cooperative

Project Summary/Abstract The Tennessee Department of Health (TDH) is a long-term participant and leader in the NARMS (RFS) program. TDH feels that the expansion of the retail food arm of NARMS is critical step in conducting surveillance for antimicrobial resistance (AR) in the food chain and for monitoring the impact of recent national initiatives including important regulatory changes in the use of antimicrobials in food animals. Use of antimicrobials in food animal production creates selective pressure that enables antimicrobial resistant bacteria to matriculate into the food supply and ultimately cause human infections. Of concern, antibiotic resistant infections are accompanied by more severe illnesses, more deaths, higher healthcare costs, and increased harm to society. We feel that surveillance is critical “data-for-action” to understand the sources of AR and multi-drug resistance (MDR) in the food supply chain and to combat this public health problem. Tennessee embraces the goal of the NARMS food surveillance program to improve the detection of and surveillance for AR among enteric bacteria in raw retail meat commodities through this cooperative funding agreement (FOA # PAR-16-099, CFDA # 93.876). Tennessee will participate fully in all project components including purchase of approved meats, testing by NARMS protocols, shipment of isolates and meta data, and continued activity in the NARMS working group. Additionally, Tennessee anticipates participating in any future pilot activity or expansion to other meats or commodities. Tennessee capacity for testing meats has translated to increased ability to assess isolates and their link to human clusters, as well as more proficiency in testing meats during outbreaks and quickly characterizing the AR properties to inform the public heath investigation. Tennessee will participate fully in all NARMS RFS activities and follow the accepted protocols during the 5 year period. Our strategy include: 1. Maintain sampling and reporting with a continuous quality improvement paradigm in RFS. 2. Foster partnership among Tennessee, federal, state, local, and external partners. 3. Enhance outbreak investigation response and reporting. 4. Sustain and enhance NARMS laboratory diagnostic capacity. 6.Improve laboratory coordination, outreach, and information flow. 7. Maintain and exchange integrated surveillance information system. Tennessee's expectations and outcomes, strategies and activities, and collaborative activities will continue throughout the 5 year period with continued funding.

项目概要/摘要 田纳西州卫生部 (TDH) 是该领域的长期参与者和领导者 NARMS (RFS) 计划。 TDH 认为 NARMS 零售食品部门的扩张 是监测食品中抗菌素耐药性 (AR) 的关键一步 链并监测近期国家举措的影响，包括重要的 食用动物中抗菌药物使用的监管变化。抗菌药物的使用 食用动物生产产生选择性压力，导致抗菌药物产生耐药性 细菌进入食品供应并最终导致人类感染。的 令人担忧的是，抗生素耐药性感染伴随着更严重的疾病， 死亡、更高的医疗费用以及对社会的更大危害。我们觉得 监测是了解 AR 和多种药物来源的关键“数据促行动” 食品供应链中的耐药性（MDR）并解决这一公共卫生问题。 田纳西州拥护 NARMS 食品监测计划的目标，以改善 零售生肉中肠道细菌 AR 的检测和监测 通过此合作资助协议（FOA # PAR-16-099、CFDA # 93.876）。田纳西州将全面参与所有项目组成部分，包括购买 批准的肉类，按照 NARMS 协议进行测试，分离物和元数据的运输，以及 NARMS 工作组继续开展活动。此外，田纳西州预计 参与任何未来的试点活动或扩展到其他肉类或商品。 田纳西州的肉类检测能力已转化为评估能力的提高 分离株及其与人类群体的联系，以及更熟练地测试肉类 在疫情爆发期间快速描述 AR 特性，以便为公众健康提供信息 调查。田纳西州将全面参与所有 NARMS RFS 活动并遵循 5 年期间接受的协议。我们的策略包括： 1. 保持抽样 并通过 RFS 中的持续质量改进范例进行报告。 2.福斯特 田纳西州、联邦、州、地方和外部合作伙伴之间的伙伴关系。 3. 增强 疫情调查响应和报告。 4. 维持和加强 NARMS 实验室诊断能力。 6.改善实验室协调、外展和 信息流。 7.维护和交换综合监视信息系统。 田纳西州的期望和成果、战略和活动以及协作 活动将在持续资助的情况下在整个 5 年期间持续进行。