Enhancing Leadership Capacity to Mentor Scientists in Translational Behavioral AD-Related Research

增强领导能力，指导科学家进行转化行为 AD 相关研究

• 批准号: 9903178
• 负责人: Girardin Jean-Louis
• 金额: $ 12.58万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-15 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9903178
• 关键词: Address; Adopted; Adoption; Adult; Affect; Aging; Alzheimer' s Disease; Area; Award; Behavior Therapy; Behavioral; Behavioral Medicine; Behavioral Model; Behavioral Research; Behavioral Sciences; Cardiovascular Diseases; Clinical Research; Communities; Complement; Disease Outcome; Effectiveness; Elderly; Environment; Faculty; Fellowship; Fellowship Program; Fostering; Funding; Health; Health Benefit; Health Policy; Health Professional; Individual; Institutes; Intervention; Investments; Laboratories; Leadership; Learning; Location; Medical center; Mentors; Mentorship; Methods; Minority; New York; Outcome; Outcomes Research; Patient-Focused Outcomes; Physicians; Population; Postdoctoral Fellow; Psychiatry; Psychosocial Assessment and Care; Research; Research Institute; Research Personnel; Research Proposals; Resources; Scientist; Sleep; Sleep Disorders; Testing; Training; Translating; United States National Institutes of Health; aging population; behavior change; brain health; burden of illness; career; clinical candidate; ethnic minority population; evidence base; experience; health disparity; healthy aging; improved; innovation; interdisciplinary collaboration; peer coaching; population health; professor; programs; racial and ethnic; research to practice; sleep health; social; success; therapy development

Project Summary Community-engaged research, focusing on patient-centered outcomes (PCO), is critical in translating scientific evidence into health benefits for the aging US population. There’s limited focus on understanding associations of sleep with brain health and cardiovascular disease (CVD) among older adults, particularly minorities who are disproportionately burdened by Alzheimer’s disease (AD). Consistent with the NIH roadmap of translating research into practice, it is paramount that health professionals be trained to pursue careers in PCO that promote healthy aging. The K07 leadership award will serve as (a) a collaborative learning laboratory and (b) a resource to stimulate, support, and evaluate high-priority translational aging research in diverse communities. It will coalesce a network of renowned investigators to tackle adverse sleep-related CVD outcomes in a diverse aging population. It will also address a critical deficiency in the academic workforce by mentoring junior scientists to pursue careers in translational behavioral research and to become effective mentors. The plan builds upon Dr. Jean-Louis’ leadership in implementing community research and mentoring programs. Its strong likelihood of success is anchored by his outstanding experience engaging multiple stakeholders supporting aging-related research initiatives. The K07 plan will be implemented in an outstanding academic environment for translational behavioral research. It leverages several NYU resources, particularly those of the CTSI, the Center for Healthful Behavior Change, the Center for Brain Health, and the Sleep Disorders Center. Other enhancements to this environment include: 1) a community-academic partnership with a shared aging research agenda aiming to address important health needs of older adults, 2) access to a pool of 83 PRIDE scientists who will be coached to become Peer Mentors, and 3) Dr. Jean-Louis’ leadership in a new fellowship program in translational behavioral sciences in NYU’s Department of Population Health. Dr. Jean-Louis’ research program comprises several trials ascertaining effectiveness of tailored interventions to increase adoption of sleep health messages. These are complemented by use of mix-methods approaches to study psychosocial and cultural factors affecting health practices in diverse communities. The Specific Aims are to: 1) Provide a forum in which mid- to senior-level investigators in aging research will congregate to forge interdisciplinary collaborations, leading to submission of innovative research proposals; 2) Select and mentor 12 postdoctoral URM scientists with potential to become innovative and creative leaders in the scientific community, applying translational behavioral models to promote healthy aging; and 3) Coach 12 scientists who recently graduated from NYU’s PRIDE Institute to become Peer Mentors. This award will have a strong impact in increasing the academic workforce in sleep and ethnogerontological research.

项目摘要 社区参与的研究，重点是以患者为中心的结果（PCO），是翻译的关键 科学证据对美国老龄化人口的健康益处。对理解的关注有限 睡眠与老年人的大脑健康和心血管疾病（CVD）的关系， 少数民族谁是不成比例的负担阿尔茨海默氏病（AD）。与NIH一致 将研究转化为实践的路线图，至关重要的是，卫生专业人员要接受培训， 在PCO的职业生涯，促进健康老龄化。K 07领导奖将作为（a）一个合作 学习实验室和（B）一个资源，以刺激，支持和评估高优先级的翻译老化 在不同的社区进行研究。它将联合一个由知名调查人员组成的网络， 不同老龄化人群中睡眠相关的心血管疾病结果。它还将解决《公约》中的一个关键缺陷， 通过指导初级科学家从事转化行为研究的学术工作， 并成为有效的导师。该计划建立在Jean-Louis博士在实施 社区研究和指导计划。它成功的可能性很大， 有吸引多个利益攸关方支持老龄化相关研究举措的杰出经验。的 K 07计划将在一个优秀的学术环境中进行转化行为研究。 它利用了几个纽约大学的资源，特别是CTSI，健康行为中心的资源 改变，大脑健康中心和睡眠障碍中心。对此的其他增强 环境包括：1）社区-学术伙伴关系，共同的老龄化研究议程，旨在 解决老年人的重要健康需求，2）获得83名PRIDE科学家的帮助， 3）Jean-Louis博士在一个新的奖学金计划中的领导作用， 纽约大学人口健康系的转化行为科学。让-路易博士的研究 该计划包括几项试验，以确定量身定制的干预措施的有效性， 睡眠健康信息这些都是通过使用混合方法的方法来研究补充 影响不同社区保健做法的社会心理和文化因素。具体目标是 目的：1）提供一个论坛，让老龄化研究的中高层研究人员聚集在一起， 跨学科合作，导致提交创新的研究建议; 2）选择和 指导12名博士后URM科学家，他们有潜力成为创新和创造性的领导者， 科学界，应用转化行为模型促进健康老龄化;和3）教练12 最近从纽约大学PRIDE研究所毕业并成为同侪导师的科学家。这个奖项将 在增加睡眠和老年人种学研究的学术队伍方面产生了巨大的影响。