Enhancing Leadership Capacity to Mentor Scientists in Translational Behavioral AD-Related Research (K07)

项目摘要 社区参与的研究，关注以患者为中心的结果(PCO)，在翻译中至关重要 美国老龄化人口健康益处的科学证据。人们对理解的关注有限 老年人睡眠与脑健康和心血管疾病(CVD)的关系，尤其是 阿尔茨海默病(AD)负担过重的少数群体。与美国国立卫生研究院一致 将研究转化为实践的路线图，最重要的是培训卫生专业人员 促进健康衰老的PCO职业生涯。K07领导力奖将作为(A)协作奖 学习实验室和(B)激励、支持和评估高度优先的翻译老龄化的资源 在不同的社区进行研究。它将联合一个著名的调查人员网络来应对不利的 不同老龄化人口中与睡眠相关的心血管疾病结局。它还将解决在以下方面的一个严重缺陷 通过指导初级科学家从事翻译行为研究来培养学术队伍 并成为有效的导师。该计划建立在Jean-Louis博士在实施 社区研究和指导计划。它成功的可能性很大，这是由他的 出色的经验吸引多个利益相关者支持与老龄化相关的研究计划。这个 K07计划将在翻译行为研究的优秀学术环境中实施。 它利用了几个纽约大学的资源，特别是CTSI，健康行为中心的资源 Change、大脑健康中心和睡眠障碍中心。对此进行的其他增强 环境包括：1)社区-学术伙伴关系，共享老龄化研究议程，旨在 满足老年人的重要健康需求，2)接触83名骄傲的科学家，他们将成为 被培训成为同行导师，以及3)Jean-Louis博士在一项新的团契计划中的领导力 纽约大学人口健康系的翻译行为科学。让-路易斯博士的研究 该计划包括几个试验，以确定量身定制的干预措施的有效性，以增加对 睡眠健康信息。这些都得到了使用混合方法研究的补充 影响不同社区卫生做法的心理、社会和文化因素。具体目标是 为：1)提供一个论坛，让老龄化研究的中高级研究人员聚集在一起锻造 跨学科协作，导致提交创新的研究提案；2)选择和 指导12名有潜力成为该领域创新和创造性领导者的博士后URM科学家 科学界，应用翻译行为模式促进健康老龄化；以及3)Coach 12 最近从纽约大学骄傲研究所毕业成为同行导师的科学家们。这一奖项将 对增加睡眠和民族老年学研究的学术队伍有很大影响。

Project Summary Community-engaged research, focusing on patient-centered outcomes (PCO), is critical in translating scientific evidence into health benefits for the aging US population. There’s limited focus on understanding associations of sleep with brain health and cardiovascular disease (CVD) among older adults, particularly minorities who are disproportionately burdened by Alzheimer’s disease (AD). Consistent with the NIH roadmap of translating research into practice, it is paramount that health professionals be trained to pursue careers in PCO that promote healthy aging. The K07 leadership award will serve as (a) a collaborative learning laboratory and (b) a resource to stimulate, support, and evaluate high-priority translational aging research in diverse communities. It will coalesce a network of renowned investigators to tackle adverse sleep-related CVD outcomes in a diverse aging population. It will also address a critical deficiency in the academic workforce by mentoring junior scientists to pursue careers in translational behavioral research and to become effective mentors. The plan builds upon Dr. Jean-Louis’ leadership in implementing community research and mentoring programs. Its strong likelihood of success is anchored by his outstanding experience engaging multiple stakeholders supporting aging-related research initiatives. The K07 plan will be implemented in an outstanding academic environment for translational behavioral research. It leverages several NYU resources, particularly those of the CTSI, the Center for Healthful Behavior Change, the Center for Brain Health, and the Sleep Disorders Center. Other enhancements to this environment include: 1) a community-academic partnership with a shared aging research agenda aiming to address important health needs of older adults, 2) access to a pool of 83 PRIDE scientists who will be coached to become Peer Mentors, and 3) Dr. Jean-Louis’ leadership in a new fellowship program in translational behavioral sciences in NYU’s Department of Population Health. Dr. Jean-Louis’ research program comprises several trials ascertaining effectiveness of tailored interventions to increase adoption of sleep health messages. These are complemented by use of mix-methods approaches to study psychosocial and cultural factors affecting health practices in diverse communities. The Specific Aims are to: 1) Provide a forum in which mid- to senior-level investigators in aging research will congregate to forge interdisciplinary collaborations, leading to submission of innovative research proposals; 2) Select and mentor 12 postdoctoral URM scientists with potential to become innovative and creative leaders in the scientific community, applying translational behavioral models to promote healthy aging; and 3) Coach 12 scientists who recently graduated from NYU’s PRIDE Institute to become Peer Mentors. This award will have a strong impact in increasing the academic workforce in sleep and ethnogerontological research.