Mapping the molecular blueprint for immune cell differentitation

绘制免疫细胞分化的分子蓝图

• 批准号: nhmrc : GNT1103895
• 负责人: Prof Stephen Turner
• 金额: $ 75.33万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mapping-molecular-blueprint-cell-differentitation/1346314
• 关键词: Mapping; molecular; blueprint; immune; cell

Killer T cells are white blood cells that are key for helping control virus infections and in the recognition and elimination of cells that have become cancerous. This proposal aims to identify novel molecular mechanisms that control the ability of killer T cells to mediate their antiviral and anti-cancer functions. This will provide molecular targets for possible clinical interventions designed to either promote immunity (vaccination) or limit damage caused by T cell responses that target self

杀手T细胞是帮助控制病毒感染以及识别和消除癌变细胞的关键白细胞。这项提议旨在确定控制杀伤T细胞调节其抗病毒和抗癌功能的新的分子机制。这将为可能的临床干预提供分子靶点，旨在提高免疫力(接种疫苗)或限制针对自身的T细胞反应造成的损害