Impact of Social Cohesion and Social Capital in PrEP Uptake and Adherence Among Transwomen of Color - SGM Administrative Supplement

项目摘要 这一行政补充项目寻求使用实时地理空间方法来调查关联 关系、网络和邻里之间与艾滋病毒暴露前预防（PrEP）摄入的关系 纽约市大都会区亚裔跨性别女性（TW）的艾滋病和其他艾滋病毒相关结果 统计区（MSA）。有了这个补充，我们将招募50名亚洲TW成为NIH资助的 试图了解关系，网络和社区之间的跨性别妇女的颜色（TURNNT） 研究（R 01 MD 013554; PI：Dustin邓肯）。我们目前正在招聘200黑人和100拉丁美洲TW在 与Callen-Lorde合作使用基于诊所和社区的招募方法的TURNNT队列 社区健康中心（纽约市TW女性医疗保健的主要提供者），并通过基于场地的 招募（例如，舞蹈俱乐部）。利用与跨性别社区和临床医生建立的伙伴关系 专家，包括APICHA社区卫生中心（亚太岛民最大的服务提供商） TW纽约），沿着纽约大学亚裔美国人健康研究中心的社区合作伙伴网络， NIMHD少数民族健康和健康差异卓越中心，这一行政补充 这是一个将亚洲TW纳入研究的独特机会。资格要求包括： 亚洲跨性别女性（出生时被指定为男性，但被认定为女性，女性， 跨性别女性，跨女性，男性对女性或其他不同的跨女性性别身份的频谱）; HIV血清反应阴性; 16 - 55岁;居住在纽约市MSA;自我报告没有限制 通常的身体活动;以及自我报告愿意携带小型GPS设备一周。参加者将穿着 GPS设备遵循我们以前的可行性研究项目中使用的协议，包括 TW。这项拟议的研究将是亚洲TW艾滋病毒差异和风险的最大研究。该补充将 加速家长补助金的科学性和影响力，使我们能够接触到另一个服务不足的少数群体， 促进对亚洲人、黑人和非洲裔美国人之间的健康差距和艾滋病毒预防的跨文化比较和分析， 拉丁TW这项建议与行政补充和国家精神卫生和人类发展研究所特别关注的问题是一致的， 性和性别少数（SGM）人群，该项目将加速艾滋病毒差异的科学研究。 这项研究将提供一个具体的和细致入微的理解如何社会背景因素可能 有助于有色人种跨性别女性的艾滋病毒预防行为，这反过来又会在上下文中提供信息， 采取适当的艾滋病毒预防措施。

PROJECT SUMMARY This administrative supplement project seeks to use real-time geospatial methods to investigate associations between relationships, networks and neighborhoods in relation to HIV pre-exposure prophylaxis (PrEP) uptake and other HIV-related outcomes among Asian transgender women (TW) in the New York City metropolitan statistical area (MSA). With this supplement, we will recruit 50 Asian TW to be part of the to the NIH-funded Trying To Understand Relationships, Networks and Neighborhoods among Trans women of color (TURNNT) Study (R01MD013554; PI: Dustin Duncan). We are currently recruiting 200 Black and 100 Latina TW in the TURNNT cohort using clinic- and community-based recruitment methods in partnership with Callen-Lorde Community Health Center (a major provider of healthcare for TW women in NYC) and via venue-based recruitment (e.g., dance clubs). Leveraging established partnerships with transgender communities and clinician experts, including APICHA Community Health Center (the largest service provider for Asian and Pacific Islander TW in NYC), along with community partner networks of the NYU Center for the Study of Asian American Health, an NIMHD Center of Excellence on Minority Health and Health Disparities, this administrative supplement represents a unique opportunity to include Asian TW in the study. Eligibility requirements include: identifying as an Asian transgender woman (individuals who were assigned a male sex at birth who identify as women, female, trans women, trans female, male-to-female or another diverse trans feminine gender identity on the spectrum); HIV-seronegative; being 16 to 55 years old; residing in the New York City MSA; self-reporting no restrictions to usual physical activity; and self-report willingness to carry a small GPS device for a week. Participants will wear the GPS device following protocols used in our previous feasibility research projects, including studies among TW. The proposed study will be the largest study of HIV disparities and risk in Asian TW. This supplement will accelerate the science and impact of the parent grant, enabling us to reach another underserved minority group, fostering cross-cultural comparisons and analyses of health disparities and HIV prevention among Asian, Black and Latina TW. This proposal is aligned with the administrative supplement and NIMHD’s special attention to sexual and gender minority (SGM) populations, and this project will accelerate the science on HIV disparities. This research will provide a context-specific and nuanced understanding of how social contextual factors may contribute to HIV prevention behaviors in transgender women of color, which will in turn inform contextually appropriate HIV prevention interventions.