Impact of Social Cohesion and Social Capital in PrEP Uptake and Adherence Among Transwomen of Color - SGM Administrative Supplement

项目总结 这一行政补充项目寻求使用实时地理空间方法来调查关联 关系、网络和邻里之间与HIV暴露前预防(PrEP)感染的关系 以及纽约大都会亚裔变性女性(TW)中与艾滋病毒相关的其他结果 统计面积(MSA)。有了这个补充，我们将招募50名亚洲TW作为NIH资助的 试图了解有色人种跨性女性之间的关系、网络和社区(TURNNT) 研究(R01MD013554；PI：Dustin Duncan)。我们目前正在招聘200名黑人和100名拉丁裔TW 与Callen-Lorde合作，使用诊所和社区招募方法进行TURNNT队列 社区卫生中心(纽约市TW妇女的主要医疗保健提供者)和Via会场 招募(例如，舞蹈俱乐部)。利用与变性人社区和临床医生建立的伙伴关系 专家，包括APICHA社区卫生中心(亚洲和太平洋岛民最大的服务提供商 与纽约大学亚裔美国人健康研究中心的社区合作伙伴网络一起， NIMHD少数民族健康和健康差距卓越中心，这一行政副刊 代表着将亚洲TW纳入研究的独特机会。资格要求包括：确定为 亚洲变性女性(出生时被指定为男性的人，自认为是女性，女性， 跨性别女性、跨性别女性、男性对女性或其他不同的跨性别女性身份)； HIV血清阴性；年龄16至55岁；居住在纽约市MSA；自我报告不受限制 通常的身体活动；自我报告愿意携带一个小型GPS设备一周。参赛者将穿着 GPS设备遵循我们之前可行性研究项目中使用的协议，包括以下研究 TW.这项拟议的研究将是关于亚洲TW地区艾滋病毒差异和风险的最大研究。这份副刊将 加快家长资助的科学性和影响力，使我们能够接触到另一个服务不足的少数群体， 促进跨文化比较和分析亚裔和黑人之间的健康差距和艾滋病毒预防 和拉丁裔TW。这项建议与行政补编和NIMHD特别注意的 这一项目将加速关于艾滋病毒差异的科学研究。 这项研究将提供特定于背景的细微差别的理解，了解社会背景因素如何 促进有色人种变性人妇女的艾滋病毒预防行为，这反过来又会为背景提供信息 适当的艾滋病毒预防干预措施。

PROJECT SUMMARY This administrative supplement project seeks to use real-time geospatial methods to investigate associations between relationships, networks and neighborhoods in relation to HIV pre-exposure prophylaxis (PrEP) uptake and other HIV-related outcomes among Asian transgender women (TW) in the New York City metropolitan statistical area (MSA). With this supplement, we will recruit 50 Asian TW to be part of the to the NIH-funded Trying To Understand Relationships, Networks and Neighborhoods among Trans women of color (TURNNT) Study (R01MD013554; PI: Dustin Duncan). We are currently recruiting 200 Black and 100 Latina TW in the TURNNT cohort using clinic- and community-based recruitment methods in partnership with Callen-Lorde Community Health Center (a major provider of healthcare for TW women in NYC) and via venue-based recruitment (e.g., dance clubs). Leveraging established partnerships with transgender communities and clinician experts, including APICHA Community Health Center (the largest service provider for Asian and Pacific Islander TW in NYC), along with community partner networks of the NYU Center for the Study of Asian American Health, an NIMHD Center of Excellence on Minority Health and Health Disparities, this administrative supplement represents a unique opportunity to include Asian TW in the study. Eligibility requirements include: identifying as an Asian transgender woman (individuals who were assigned a male sex at birth who identify as women, female, trans women, trans female, male-to-female or another diverse trans feminine gender identity on the spectrum); HIV-seronegative; being 16 to 55 years old; residing in the New York City MSA; self-reporting no restrictions to usual physical activity; and self-report willingness to carry a small GPS device for a week. Participants will wear the GPS device following protocols used in our previous feasibility research projects, including studies among TW. The proposed study will be the largest study of HIV disparities and risk in Asian TW. This supplement will accelerate the science and impact of the parent grant, enabling us to reach another underserved minority group, fostering cross-cultural comparisons and analyses of health disparities and HIV prevention among Asian, Black and Latina TW. This proposal is aligned with the administrative supplement and NIMHD’s special attention to sexual and gender minority (SGM) populations, and this project will accelerate the science on HIV disparities. This research will provide a context-specific and nuanced understanding of how social contextual factors may contribute to HIV prevention behaviors in transgender women of color, which will in turn inform contextually appropriate HIV prevention interventions.