The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
基本信息
- 批准号:9983211
- 负责人:
- 金额:$ 32.2万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-08-15 至 2023-07-31
- 项目状态:已结题
- 来源:
- 关键词:Academic Medical CentersAcuteAdultAgeAreaBlood VesselsCause of DeathCerebrovascular DisordersCertificationChildChildhoodClinicalClinical ResearchClinical TrialsClinical Trials DesignCommunicationConduct Clinical TrialsData CollectionDevelopmentDisciplineDiseaseEducationEmergency Department PhysicianEnrollmentFeedbackFundingFutureGenerationsGeographyGoalsHospitalsInfrastructureInterventionKnowledgeLeadershipMentorsMissionMonitorNeurologistNeurosurgeonNursesParticipantPatient RecruitmentsPatientsPediatric HospitalsPennsylvaniaPhasePhiladelphiaPreventionPrevention therapyPrincipal InvestigatorProceduresProductivityProtocols documentationPublic HealthRecoveryRehabilitation therapyResearchResearch EthicsResearch PersonnelResearch Project GrantsResearch SupportResearch TrainingResourcesRhode IslandScientistSiteSpecialistStrokeStrokeNet trialsStructureSurgeonTalentsTimeTrainingTraining and EducationTranslational ResearchUnited StatesUnited States National Institutes of HealthUniversitiesWorkbasecareerclinical practicedata exchangedata managementethnic diversityexperiencefollow-uphuman subject protectioninnovationmembermulti-site trialmultidisciplinaryneonatenovel therapeuticsoperationpatient populationprogramsrecruitskillsstroke clinical trialsstroke interventionstroke patientstroke therapystroke trialssuburbtertiary care
项目摘要
The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC) is a highly effective
collaborative stroke research team comprised of adult and pediatric vascular neurologists, neurosurgeons,
neuroradiologists, emergency physicians, rehabilitation specialists, and other experts who conduct clinical trials
focused on stroke treatment, prevention, and recovery. The PRSTNCC is based at the University of
Pennsylvania (Penn), an urban, tertiary care, academic medical center in Philadelphia, PA, which serves as
the "Hub" of the consortium, and has joined forces with the Children's Hospital of Philadelphia (CHOP) and 8
additional member hospitals ("Spokes") located in geographically and ethnically diverse areas in and around
Philadelphia (and 1 in Rhode Island). The PRSTNCC thereby unites comprehensive stroke centers, primary
stroke centers, and a regional pediatric center, providing access to a broad range of patients with stroke to a
multidisciplinary group of clinicians and researchers. The overarching goal of the PRSTNCC is to reduce the
burden of stroke among patients of all ages and backgrounds within this region by conducting interdisciplinary
trials of promising clinical interventions for stroke treatment, prevention, and recovery.
The multi-disciplinary PRSTNCC leadership team, led by Principal Investigator (PI) Scott E. Kasner, MD, has
extensive experience conducting multi-center stroke clinical trials, and has been a leading enroller for the
current NIH StrokeNet. The PRSTNCC infrastructure supports efficient and effective conduct of stroke trials
among the participant hospitals. Research support and expertise are provided by the Hub, particularly in the
areas of human subjects protections and other regulatory activities, and education and orientation of clinical
and research staff in an effort to streamline trial implementation and expedite patient enrollment. The Hub
provides ongoing support for data collection and transfer during trial execution, and provides timely feedback
and education about trial results to member specialists and hospitals to encourage translation of research
results into clinical practice. In addition, we are training a new generation of stroke researchers in the conduct
and design of clinical trials by providing them with the knowledge and skills necessary for a successful
academic career as independently-funded clinician-scientists.
费城地区中风试验网络协调中心(PRSTNCC)是一家高效的
由成人和儿童血管神经学家、神经外科医生、
神经放射科医生、急诊医生、康复专家和其他进行临床试验的专家
专注于中风的治疗、预防和康复。PRSTNCC的总部设在加州大学
宾夕法尼亚州(宾夕法尼亚州),宾夕法尼亚州费城的一个城市,三级护理,学术医疗中心,提供
该联盟的“枢纽”,并已与费城儿童医院(CHOP)和8
位于地理和种族不同地区的其他成员医院(Spokes)及其周围
费城(罗德岛有1个)。因此,PRSTNCC将综合卒中中心、初级卒中中心
中风中心和地区性儿科中心,为范围广泛的中风患者提供
临床医生和研究人员组成的多学科小组。PRSTNCC的总体目标是减少
在本地区所有年龄和背景的患者中进行跨学科研究的卒中负担
中风治疗、预防和康复的有前景的临床干预试验。
由首席调查员(PI)Scott E.Kasner,MD领导的多学科PRSTNCC领导团队已经
具有丰富的进行多中心卒中临床试验的经验,并一直是
目前的NIH StrokeNet。PRSTNCC基础设施支持高效和有效地进行中风试验
在参与的医院中。研究支持和专业知识由中心提供,特别是在
人类受试者保护和其他监管活动领域,以及临床教育和指导
和研究人员,努力简化试验实施和加快患者登记。The Hub
为试运行期间的数据收集和传输提供持续支持,并提供及时反馈
并对成员专家和医院进行关于试验结果的教育,以鼓励研究成果的翻译
结果应用于临床实践。此外,我们正在培训新一代中风研究人员在
以及设计临床试验,为他们提供成功的
学术生涯为独立资助的临床医生-科学家。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
SCOTT E KASNER其他文献
SCOTT E KASNER的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('SCOTT E KASNER', 18)}}的其他基金
The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
10851524 - 财政年份:2023
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
10760579 - 财政年份:2023
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
10460589 - 财政年份:2018
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
9755530 - 财政年份:2018
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network Coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
10306024 - 财政年份:2018
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
8895433 - 财政年份:2013
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
8739335 - 财政年份:2013
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
9353515 - 财政年份:2013
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
9324041 - 财政年份:2013
- 资助金额:
$ 32.2万 - 项目类别:
The Philadelphia Regional Stroke Trials Network coordinating Center (PRSTNCC)
费城地区卒中试验网络协调中心 (PRSTNCC)
- 批准号:
8661987 - 财政年份:2013
- 资助金额:
$ 32.2万 - 项目类别:
相似海外基金
Un/kindness, shame & resistance: the care of inpatients in NHS adult acute mental health units and how it might be improved
Un/善良,羞耻
- 批准号:
2885806 - 财政年份:2023
- 资助金额:
$ 32.2万 - 项目类别:
Studentship
Post-Acute Care Transitions for Older Adult Medicare Beneficiaries with Serious Mental Illness
患有严重精神疾病的老年医疗保险受益人的急性后护理过渡
- 批准号:
10772386 - 财政年份:2023
- 资助金额:
$ 32.2万 - 项目类别:
Paving The Way to a Canadian Standard of Care with CAR-T Cellular Therapy: Phase II Trial of CD19 CAR-T for Relapsed/Refractory Adult Acute Lymphoblastic Leukemia (CLIC-01A)
通过 CAR-T 细胞疗法为加拿大护理标准铺平道路:CD19 CAR-T 治疗复发/难治性成人急性淋巴细胞白血病的 II 期试验 (CLIC-01A)
- 批准号:
474619 - 财政年份:2022
- 资助金额:
$ 32.2万 - 项目类别:
Operating Grants
Investigating the impact acute inhalation of cannabis with a high content of delta-9-tetrahydrocannabinol has on myelination and microglia in adult and aged mice
研究急性吸入高含量 delta-9-四氢大麻酚的大麻对成年和老年小鼠髓鞘形成和小胶质细胞的影响
- 批准号:
485965 - 财政年份:2022
- 资助金额:
$ 32.2万 - 项目类别:
Studentship Programs
Paving The Way to a Canadian Standard of Care with CAR-T Cellular Therapy: Phase II Trial of CD19 CAR-T for Relapsed/Refractory Adult Acute Lymphoblastic Leukemia (CLIC-01A)
通过 CAR-T 细胞疗法为加拿大护理标准铺平道路:CD19 CAR-T 治疗复发/难治性成人急性淋巴细胞白血病的 II 期试验 (CLIC-01A)
- 批准号:
466358 - 财政年份:2022
- 资助金额:
$ 32.2万 - 项目类别:
Operating Grants
Metabolomics for prediction of cisplatin mediated acute kidney injury: a Canadian multi-centre adult and pediatric study
预测顺铂介导的急性肾损伤的代谢组学:加拿大多中心成人和儿童研究
- 批准号:
402040 - 财政年份:2019
- 资助金额:
$ 32.2万 - 项目类别:
Operating Grants
Study of pathogenic mechanism of age-dependent chromosome translocation in adult acute lymphoblastic leukemia
成人急性淋巴细胞白血病年龄依赖性染色体易位发病机制研究
- 批准号:
18K16103 - 财政年份:2018
- 资助金额:
$ 32.2万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Causal effect of time-varying driving pressures on mortality in mechanically ventilated, adult patients with acute respiratory distress syndrome
时变驱动压力对机械通气成年急性呼吸窘迫综合征患者死亡率的因果影响
- 批准号:
377313 - 财政年份:2017
- 资助金额:
$ 32.2万 - 项目类别:
Studentship Programs
Role of SETBP1 in adult Ph+ acute lymphoblastic leukemia
SETBP1 在成人 Ph 急性淋巴细胞白血病中的作用
- 批准号:
9315111 - 财政年份:2016
- 资助金额:
$ 32.2万 - 项目类别:
Acute Inhibition of Adult-born Granule Cells and its Effect on Antidepressant Act
成体颗粒细胞的急性抑制及其抗抑郁作用
- 批准号:
8734273 - 财政年份:2013
- 资助金额:
$ 32.2万 - 项目类别: