Enhancing Sleep Duration: Effects of Children's Eating and Activity Behaviors

延长睡眠时间：儿童饮食和活动行为的影响

• 批准号: 10204076
• 负责人: Chantelle Nobile Hart
• 金额: $ 69.09万
• 依托单位: TEMPLE UNIV OF THE COMMONWEALTH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10204076
• 关键词: 11 year old; Accelerometer; Address; Adult; Affect; African American; Behavior; Behavior Therapy; Behavioral; Beverages; Body mass index; Cardiovascular system; Child; Childhood; Eating; Eating Behavior; Energy Intake; Enrollment; Epidemic; Evaluation; Food; Health; Height; Hour; Informal Social Control; Intervention; Learning; Lipids; Low income; Maintenance; Measures; Motivation; Nature; Not Hispanic or Latino; OGTT; Obesity; Observational Study; Outcome Study; Overweight; Pathway interactions; Persons; Phase; Physical activity; Prevention approach; Process; Race; Randomized; Randomized Controlled Trials; Regulation; Regulatory Pathway; Reporting; Rewards; Risk; Risk Factors; Risk Reduction; Role; School-Age Population; Signal Transduction; Sleep; Telephone; Television; Time; Underserved Population; Weight; Weight Gain; Work; actigraphy; base; behavior change; blood glucose regulation; cardiometabolic risk; cardiometabolism; cardiovascular risk factor; clinically significant; dietary; experimental study; follow-up; health disparity; healthy weight; high risk population; improved; intervention effect; moderate-to-vigorous physical activity; novel strategies; obesity in children; obesity prevention; obesity risk; overweight child; preventive intervention; racial and ethnic disparities; racial minority; socioeconomics; waist circumference

PROJECT SUMMARY/ABSTRACT Thirty four percent of school-age children are overweight or obese with clear obesity- and cardiovascular (CV)- related health disparities among racial groups. There have been calls to assess novel approaches for prevention of obesity and CV risk, particularly for African-American (AA)/black children. Given their increased risk of short sleep, obesity and CV disturbance, one approach that may be promising for children who are AA/Black is enhancing sleep duration. Observational studies with children demonstrate that short sleep increases risk of obesity and other CV risk factors. Experimental studies with adults document that changes in sleep may influence obesity risk primarily through eating pathways. Our own randomized controlled trials with children 8-11 years old provide a robust signal that enhancing sleep duration leads to decreases in: motivation for food, reported food intake and TV viewing; and increases in physical activity-with a net result of positive changes in weight status and potential changes in glucose regulation, particularly for children who enhance their sleep the most. However, preliminary studies are limited by short study timeframes (2-weeks to 2- months), primary enrollment of non-Hispanic White children, and primary aims focused on eating behaviors rather than obesity or other CV risk. In this competing renewal we propose addressing these limitations by enrolling children who are AA/black, assessing effects of intervention over a 12-month period, and focusing the primary aim on change in zBMI. Specifically, we propose rigorous evaluation of two active preventive interventions: a) enhancing sleep alone (Optimize Sleep [OS]), and b) enhancing sleep along with eating and activity behaviors that have demonstrated efficacy for obesity prevention and are implicated in self-regulatory pathways related to sleep (i.e., energy dense snack foods and beverages, TV viewing, and physical activity) (OS-Plus). The present study proposes to enroll 204 children 8-11 years old who are AA/black, primarily from low socioeconomic backgrounds, and who sleep < 9.5 hours/night into a 12-month study. Children will be randomly assigned to either OS or OS-Plus. Over the 6-month treatment phase, all children will attend an 8- session treatment (4 in-person & 4 phone follow-up) in which they will learn effective behavioral strategies to improve sleep duration (OS) or improve sleep and targeted eating and activity behaviors (OS-Plus); there will be monthly phone contact during the maintenance period (6-12 months). At baseline, end of treatment (6 months), and 12 months, the following will be measured: sleep duration (actigraphy), eating behaviors (24-hour dietary recalls, eating self regulation), physical activity (accelerometry), anthropometrics (height, weight, waist circumference), and additional cardiometabolic risk factors (adiposity, lipids, and glucose regulation). Primary aim is to determine the efficacy of OS-Plus relative to OS on change in body mass index z-score (BMIz) at end of treatment. Secondary aims will assess efficacy of OS-Plus relative to OS on additional cardiometabolic risk factors, eating and activity behaviors. Exploratory aims will assess maintenance of effects at 12 months.

项目摘要/摘要 有34％的学龄儿童超重或肥胖，肥胖和心血管（CV） - 种族群体之间的相关健康差异。有呼吁评估新颖方法 预防肥胖和简历风险，特别是对于非裔美国人（AA）/黑人儿童。考虑到他们的增加 睡眠短，肥胖和简历干扰的风险，这是一种有希望的方法 AA/黑色正在增强睡眠时间。与儿童的观察性研究表明睡眠短暂 增加肥胖和其他简历风险因素的风险。与成年人有关的实验研究有所改变 睡眠可能主要通过饮食途径影响肥胖风险。我们自己的随机对照试验与 8-11岁的儿童提供了一个强大的信号，增强睡眠时间会导致减少：动机 对于食物，据报道食物摄入量和电视观看；并增加体育锻炼，阳性的净结果 体重状况的变化和葡萄糖调节的潜在变化，特别是对于增强的儿童 他们的睡眠最多。但是，初步研究受到简短的研究时间表的限制（2周至2-- 几个月），非西班牙裔白人儿童的主要入学人数，主要目的是饮食行为 而不是肥胖或其他简历风险。在这种竞争的续约中，我们建议通过 注册AA/黑色的儿童，评估12个月内干预的影响，并集中于 ZBMI改变的主要目的。具体而言，我们提出对两个主动预防性的严格评估 干预措施：a）单独增强睡眠（优化睡眠[OS]），b）随着进食和 表现出对预防肥胖的功效并与自我调节有关的活动行为 与睡眠有关的途径（即能量密集的零食和饮料，电视观看和体育锻炼） （OS-Plus）。本研究提议注册204名8-11岁儿童AA/黑色，主要来自 社会经济背景低下，在一项为期12个月的研究中睡觉<9.5小时/夜。孩子会 随机分配给OS或OS-Plus。在6个月的治疗阶段，所有儿童将参加8- 会议治疗（4个面对面和4个电话随访），他们将学习有效的行为策略 改善睡眠持续时间（OS）或改善睡眠和目标饮食和活动行为（OS-Plus）；会在那里 在维护期（6-12个月）期间每月联系。在基线时，治疗结束（6 月份和12个月，将测量以下内容：睡眠持续时间（Actraphy），饮食行为（24小时 饮食召回，饮食自我调节），体育锻炼（加速度计），人体测量法（身高，体重，腰部 周长）和其他心脏代谢危险因素（肥胖，脂质和葡萄糖调节）。基本的 目的是确定相对于OS相对于OS的疗效在结束时体重指数Z分数（BMIZ）的变化 治疗。次要目的将评估OS-相对于OS的效力，而OS对其他心脏代谢风险 因素，饮食和活动行为。探索目的将评估12个月后影响的维持。

项目成果

Development of a Behavioral Sleep Intervention as a Novel Approach for Pediatric Obesity in School-aged Children.

• DOI: 10.1016/j.pcl.2016.02.007
• 发表时间: 2016-06
• 期刊: Pediatric clinics of North America
• 影响因子: 2.6
• 作者: Hart CN;Hawley NL;Wing RR
• 通讯作者: Wing RR

Randomized controlled trial to enhance children's sleep, eating, and weight.

• DOI: 10.1038/s41390-021-01870-3
• 发表时间: 2022-10
• 期刊: Pediatric research
• 影响因子: 3.6
• 作者: Hart CN;Hawley NL;Coffman DL;Raynor HA;Carskadon MA;Jelalian E;Owens JA;Spaeth A;Wing RR
• 通讯作者: Wing RR