Omics and Symptom Science Training Program

组学和症状科学培训计划

• 批准号: 10205176
• 负责人: Margaret McLean Heitkemper
• 金额: $ 28.81万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10205176
• 关键词: Training Programs; symptom science

In 2011, the Genomic Nursing State of the Science Advisory Panel developed a Blueprint for Nursing Science which included the need to develop the next generation of nursing scientists poised to lead interdisciplinary teams that integrate omics-based measures with clinical outcomes research. To accomplish this, a concerted effort needs to be made in the training of nursing science doctoral students and postdoctoral trainees with skills necessary to incorporate and evaluate omics in health and disease. More recently a focus on precision health has been advocated by NIH and NINR. This new emphasis brings with it the need for a larger cadre of nurse scientists who understand, appreciate, and utilize scientific advances in the fields of genetics, transcriptomics, metabolomics and the microbiome. The integration of omics in nursing science programs is needed to fully understand biologic mechanisms underlying symptoms and function in order to advance individualized healthcare and to optimize treatment and outcomes. Given nursing’s tradition of utilizing biobehavioral information in concert with patient and family assessments, the development of nurse scientists with complementary skills in the interpretation and clinical integration (i.e., translation) of data derived from new technologies is imperative. With the development of new technologies that can capture molecular characteristics, new innovative approaches to enhance health and reduce symptom burden can be developed and tested. The University of Washington School of Nursing (UW SoN) has a long history in building biobehavioral nursing science capacity. Prior and on-going work by nurse scientists at UW SoN incorporates basic bench science in concert with clinical and laboratory studies of diverse patient groups, and translated their findings to clinical practice. Our goal now is to expand this capacity by integrating omics tools and interdisciplinary educational approaches into our doctoral and postdoctoral training. The specific aims for the proposed Omics and Symptom Science Training Program (OSSTP) are 1) to recruit and retain a qualified diverse cadre of pre-doctoral and post-doctoral trainees, 2) to provide interdisciplinary didactic research training in the fundamental theories, methods, and skills necessary to conduct research that includes omics measures in concert with symptoms, 3) to facilitate the ability of trainees to develop research expertise through ongoing research experience in omics and symptom science, 4) to mentor all trainees in the ethical conduct of research, especially in diverse vulnerable populations, and 5) to recognize the ethical implications of omics measures in nursing research. Our goal is to train 3 predoctoral trainees and 2 postdoctoral trainees annually for 5 years. Training program structures, processes, and outcomes will be evaluated on an ongoing basis.

2011年，科学咨询小组的基因组护理状态开发了护理科学蓝图 其中包括开发下一代护士科学家中毒以领导跨学科的需要 将基于OMIC的措施与临床结果研究相结合的团队。为此，一个协调一致的 在培训护士科学博士生和学术博士学位学员的培训中，需要努力 在健康和疾病中纳入和评估OMICS所必需的。最近，专注于精确健康 NIH和NINR提倡。这种新的重点带来了更大的护士干部 理解，欣赏和利用遗传学，转录组学领域的科学进步的科学家， 代谢组学和微生物组。需要在护士科学计划中的OMICS整合才能完全 了解症状和功能的生物学机制，以提高个性化 医疗保健并优化治疗和结果。鉴于护士使用生物行为的传统 与患者和家庭评估一致的信息，由 在解释和临床整合（即翻译）中的完全技能 技术是必须的。随着可以捕获分子的新技术的发展 可以开发特征，新的创新方法来增强健康并减轻症状伯恩 并经过测试。华盛顿大学护理学院（UW SON）在建造方面有很长的历史 生物行为护士科学能力。 UW Son Incorporated的护士科学家的事先和正在进行的工作 与潜水员群体的临床和实验室研究共同基础基础科学，并翻译 他们对临床实践的发现。我们现在的目标是通过整合OMICS工具和 跨学科的教育方法进入我们的博士和博士后培训。具体目标 拟议的OMICS和症状科学培训计划（OSSTP）是1）招募和保留合格的 博士前和博士后学员的多元化干部，2）提供跨学科的教学研究 在进行包括OMIC在内的研究所需的基本理论，方法和技能的培训 与符号共同采取的措施，3）促进学员通过 OMICS和症状科学的持续研究经验，4）在所有学员的心理上 研究，特别是在潜水员脆弱人群中，5）认识到OMICS的道德意义 护士研究的措施。我们的目标是每年培训3名专用学员和2名博士后学员 5年。培训计划结构，过程和结果将持续评估。