Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Evaluating Intervention Outcomes for Individuals, Systems, and Communities

整体项目总结 在我们最初获奖的4.5年里，我们成立了CHILISH(健康经济中心) 物质使用障碍、丙型肝炎病毒和艾滋病毒的治疗干预)作为国家卓越中心 与药物使用障碍政策和吸毒者丙型肝炎病毒和艾滋病毒护理相关的卫生经济研究 物质。我们独特的多机构中心利用优秀的研究人员与以下领域的协同 专业知识。在最初的获奖期，我们的目标是解决综合医疗保健的需求 系统付款人和提供者。珍惜指导和投入，从而增加了关键的经济 评估提供给个别参与者的治疗的比较有效性研究的组成部分 在医疗保健或SUD治疗环境中，包括评估在卫生部门提供的干预措施- 系统或组织级别。在此更新期间，我们建议扩大我们的重点，以增加经济 构成部分，制定经济方法，改进卫生知识转化战略 在个人、系统和社区层面进行的成果和实施研究。 我们的提案，题为“物质使用障碍、丙型肝炎病毒和艾滋病毒治疗的健康经济学：评估 个人、系统和社区的干预结果“的总体目标是发展和 传播关于医疗保健利用、健康结果和与健康相关的卫生经济学研究 影响药物使用障碍治疗政策和吸毒者丙型肝炎病毒和艾滋病护理的行为 物质。该中心包括3个研究支持核心(方法学核心、人口数据和建模 核心，传播和政策核心)，作为试点研究项目的试点赠款和培训核心 核心和管理核心。方法论核心将继续其非常成功的磋商 并将在执行研究和适应性研究中开发与经济评估有关的新方法 干预措施。新的人口数据和建模核心将借鉴核心成员在 马萨诸塞州推动人口层面经济评估的州数据联系的新方法， 并将支持一个研究联盟，该联盟为这些人群改进模拟建模方法。这个 传播与政策核心将继续参与传播科学活动，直接协助 研究团队和进一步的科学，继续举行两年一次的利益相关者会议，并制定新的 知识传播课程。试点助学金和培训核心将继续使用来自 其他核心和研究附属机构，以选择、评估和指导竞争试点获奖者，将 开展新的培训和指导活动，并将领导中心的多样性倡议。这个 管理核心将继续为所有核心提供基础设施和领导力。

OVERALL PROJECT SUMMARY In the 4.5 years since our initial award, we have established CHERISH (Center for Health Economics of Treatment Interventions for Substance Use Disorder, HCV, and HIV) as a National Center of Excellence for health economic research related to substance use disorder policy and HCV and HIV care of people who use substances. Our unique multi-institutional center leverages outstanding researchers with synergistic areas of expertise. In the initial award period, our aims have focused on addressing the needs of integrated healthcare system payers and providers. CHERISH guidance and input has resulted in addition of critical economic components to comparative effectiveness studies that evaluate treatments delivered to individual participants in healthcare or SUD treatment settings, including those evaluating interventions delivered at the health- system or organization level. In this renewal period, we propose to expand our focus to add economic components, develop economic methodologies, and improve knowledge translation strategies for health outcome and implementation research that is conducted at the individual, system, and community levels. Our proposal, entitled: “Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Evaluating Intervention Outcomes for Individuals, Systems, and Communities,” has the overall aim to develop and disseminate health economic research on healthcare utilization, health outcomes, and health-related behaviors that informs substance use disorder treatment policy and HCV and HIV care of people who use substances. The Center includes 3 Research Support Cores (Methodology Core, Population Data & Modeling Core, and Dissemination & Policy Core), a Pilot Grant & Training Core that serves as the Pilot Research Project Core, and an Administrative Core. The Methodology Core will continue its highly successful Consultation Service and will develop new methods related to economic evaluation in implementation studies and adaptive interventions. The new Population Data & Modeling Core will draw on recent experience of Core members in Massachusetts to promote new approaches to state data linkages for population-level economic evaluations, and will support a research consortium that advances simulation modeling methods for these populations. The Dissemination & Policy Core will continue to engage in dissemination science activities that directly assist research teams and further the science, continue to hold bi-annual stakeholder conferences, and develop a new knowledge dissemination curriculum. The Pilot Grant & Training Core will continue to use experts from the other Cores and Research Affiliates to select, evaluate, and mentor competitive pilot grant awardees, will conduct new training and mentorship activities, and will lead a diversity initiative for the Center. The Administrative Core will continue to provide infrastructure and leadership to all Cores.