Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Evaluating Intervention Outcomes for Individuals, Systems, and Communities

药物滥用障碍、丙型肝炎病毒和艾滋病毒治疗的健康经济学：评估个人、系统和社区的干预结果

• 批准号: 10597210
• 负责人: Bruce R Schackman
• 金额: $ 159万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10597210
• 关键词: Address; Area; Award; Caring; Clinical; Communication; Communities; Consultations; Data; Data Linkages; Data Set; Development; Economics; Educational Curriculum; Ensure; Evaluation; Evaluation Methodology; Evaluation Research; Funding Opportunities; Grant; HIV; HIV/HCV; Health; Health behavior; Health system; Healthcare; Hepatitis C virus; Individual; Infrastructure; Institution; Integrated Health Care Systems; Intervention; Knowledge; Lead; Leadership; Link; Massachusetts; Mentors; Mentorship; Methodology; Methods; Modeling; Outcome; Outcomes Research; Participant; Persons; Policies; Policy Maker; Population; Provider; Records; Research; Research Personnel; Research Project Grants; Research Support; Resources; Science; Scientific Advances and Accomplishments; Services; Structure; Substance Use Disorder; System; Training; Training Activity; Translating; Treatment outcome; Work; adaptive intervention; advanced simulation; comparative effectiveness study; design; dissemination science; economic evaluation; experience; health care service utilization; health economics; implementation intervention; implementation research; implementation study; improved; interest; knowledge base; knowledge translation; member; models and simulation; novel strategies; programs; substance use; substance use treatment; symposium; tool; translational approach

OVERALL PROJECT SUMMARY In the 4.5 years since our initial award, we have established CHERISH (Center for Health Economics of Treatment Interventions for Substance Use Disorder, HCV, and HIV) as a National Center of Excellence for health economic research related to substance use disorder policy and HCV and HIV care of people who use substances. Our unique multi-institutional center leverages outstanding researchers with synergistic areas of expertise. In the initial award period, our aims have focused on addressing the needs of integrated healthcare system payers and providers. CHERISH guidance and input has resulted in addition of critical economic components to comparative effectiveness studies that evaluate treatments delivered to individual participants in healthcare or SUD treatment settings, including those evaluating interventions delivered at the health- system or organization level. In this renewal period, we propose to expand our focus to add economic components, develop economic methodologies, and improve knowledge translation strategies for health outcome and implementation research that is conducted at the individual, system, and community levels. Our proposal, entitled: “Health Economics of Substance Use Disorder, HCV, and HIV Treatment: Evaluating Intervention Outcomes for Individuals, Systems, and Communities,” has the overall aim to develop and disseminate health economic research on healthcare utilization, health outcomes, and health-related behaviors that informs substance use disorder treatment policy and HCV and HIV care of people who use substances. The Center includes 3 Research Support Cores (Methodology Core, Population Data & Modeling Core, and Dissemination & Policy Core), a Pilot Grant & Training Core that serves as the Pilot Research Project Core, and an Administrative Core. The Methodology Core will continue its highly successful Consultation Service and will develop new methods related to economic evaluation in implementation studies and adaptive interventions. The new Population Data & Modeling Core will draw on recent experience of Core members in Massachusetts to promote new approaches to state data linkages for population-level economic evaluations, and will support a research consortium that advances simulation modeling methods for these populations. The Dissemination & Policy Core will continue to engage in dissemination science activities that directly assist research teams and further the science, continue to hold bi-annual stakeholder conferences, and develop a new knowledge dissemination curriculum. The Pilot Grant & Training Core will continue to use experts from the other Cores and Research Affiliates to select, evaluate, and mentor competitive pilot grant awardees, will conduct new training and mentorship activities, and will lead a diversity initiative for the Center. The Administrative Core will continue to provide infrastructure and leadership to all Cores.

总体项目摘要 自首次奖励以来的4。5年中，我们建立了珍惜（卫生经济中心 用于药物使用障碍，HCV和HIV的治疗干预措施是国家卓越中心 与药物使用障碍政策有关的健康经济研究以及使用的人的HCV和HIV护理 物质。我们独特的多机构中心利用具有协同领域的杰出研究人员 专业知识。在最初的奖励期内，我们的目标致力于满足综合医疗保健的需求 系统付款人和提供商。除了关键的经济外，还导致了珍贵的指导和意见 比较有效性研究的组成部分，评估交付给个人参与者的治疗方法 在医疗保健或SUD治疗环境中，包括评估在健康中提供的干预措施的情况 系统或组织级别。在这个续签时期，我们建议扩大我们的重点以增加经济 组件，开发经济方法并改善健康知识翻译策略 在个人，系统和社区层面进行的结果和实施研究。 我们的建议，题为：“药物使用障碍，HCV和HIV治疗的健康经济学：评估 对个人，系统和社区的干预结果“具有发展和发展的总体目标 传播有关医疗保健利用，健康结果和与健康有关的健康经济研究 为使用使用障碍障碍治疗政策的行为以及使用的人的HCV和艾滋病毒护理 物质。该中心包括3个研究支持核心（方法论核心，人口数据和建模） 核心，传播与政策核心），这是试点赠款和培训核心，作为试点研究项目 核心和行政核心。方法核心将继续其非常成功的咨询 服务并将开发与实施研究和适应性经济评估有关的新方法 干预措施。新的人群数据和建模核心将利用核心成员的最新经验 马萨诸塞州促进新的方法来实现人口级经济评估的数据联系， 并将支持一个研究联盟，该联盟推进了这些人群的模拟建模方法。这 传播与政策核心将继续从事直接协助的传播科学活动 研究团队和进一步的科学，继续举行两年一次的利益相关者会议，并开发新的 知识传播课程。飞行员赠款和培训核心将继续使用 其他核心和研究分支机构选择，评估和精神竞争性试点赠款授予者，将 进行新的培训和心态活动，并将领导该中心的多样性倡议。 行政核心将继续为所有核心提供基础设施和领导力。

项目成果

Keep It Up! 3.0: Study protocol for a type III hybrid implementation-effectiveness cluster-randomized trial.

继续努力吧！

• DOI: 10.1016/j.cct.2023.107134
• 发表时间: 2023
• 期刊: Contemporary clinical trials
• 影响因子: 2.2
• 作者: Mustanski,Brian;Saber,Rana;Jones,JustinPatrick;Macapagal,Kathryn;Benbow,Nanette;Li,DennisH;Brown,CHendricks;Janulis,Patrick;Smith,JustinD;Marsh,Elizabeth;Schackman,BruceR;Linas,BenjaminP;Madkins,Krystal;Swann,Gregory;Dean
• 通讯作者: Dean

Are decreases in drug use risk associated with reductions in HIV sex risk behaviors among adults in an urban hospital primary care setting?

城市医院初级保健机构中成年人吸毒风险的降低是否与艾滋病毒性风险行为的减少相关？

• DOI: 10.1016/j.pmedr.2016.08.001
• 发表时间: 2016
• 期刊: Preventive medicine reports
• 影响因子: 2.8
• 作者: Walter,AngelaWangari;Cheng,DebbieM;Lloyd-Travaglini,ChristineA;Samet,JeffreyH;Bernstein,Judith;Saitz,Richard
• 通讯作者: Saitz,Richard

Ending HIV in the United States Will Require a Substantial Financial Commitment.

在美国消灭艾滋病毒需要大量的财政承诺。

• DOI: 10.7326/m21-3607
• 发表时间: 2021
• 期刊: Annals of internal medicine
• 影响因子: 39.2
• 作者: Linas,BenjaminP

Establishing a Protocol for Determining the Costs of an Integrated Set of Evidence-based Practices Aimed at Reducing Opioid Overdose Deaths.

制定一项协议，确定旨在减少阿片类药物过量死亡的一套综合循证实践的成本。

• DOI: 10.1097/adm.0000000000001218
• 发表时间: 2024
• 期刊: Journal of addiction medicine
• 影响因子: 5.5
• 作者: Tin,Yjuliana;Castry,Mathieu;Bowers-Sword,Rachel;Shantharam,Shruti;Aldridge,Arnie;Zarkin,GaryA;Starbird,Laura;Linas,BenjaminP;Barocas,JoshuaA;Morgan,JakeR
• 通讯作者: Morgan,JakeR

Costs of opioid overdose education and naloxone distribution in New York City.

• DOI: 10.1080/08897077.2021.1986877
• 发表时间: 2022
• 期刊: SUBSTANCE ABUSE
• 影响因子: 3.5
• 作者: Behrends, Czarina N.;Gutkind, Sarah;Winkelstein, Emily;Wright, Monique;Dolatshahi, Jennifer;Welch, Alice;Paone, Denise;Kunins, Hillary V.;Schackman, Bruce R.
• 通讯作者: Schackman, Bruce R.