Regional Prospective Observational Research in Tuberculosis (RePORT) India Consortium (RePORT-India)

结核病区域前瞻性观察研究（报告）印度联盟（报告-印度）

• 批准号: 10230018
• 负责人: MICHAEL DIGNAM
• 金额: $ 200万
• 依托单位: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10230018
• 关键词: Acquired Immunodeficiency Syndrome; Basic Science; Biological Markers; Biotechnology; Charge; Clinical; Clinical Research; Collaborations; Country; Data; Data Collection; Diagnosis; Diagnostic; Disease; Drug resistance; Drug resistance in tuberculosis; Enrollment; Fostering; Funding; Goals; Government; HIV; Household; India; Infrastructure; Lead; Medical Research; Observation in research; Participant; Patients; Pharmaceutical Preparations; Population; Postdoctoral Fellow; Prevention Research; Pulmonary Tuberculosis; Research; Research Personnel; Research Project Grants; Resistance; Sampling; Science; Specimen; Treatment outcome; Tuberculosis; United States National Institutes of Health; Vaccines; biobank; clinical care; clinical research site; co-infection; cohort; comorbidity; design; infection risk; programs; prospective; treatment research; tuberculosis drugs

RePORT India is a jointly funded project between the U.S. NIH/Division of AIDS (DAIDS), NIH/OAR and the Government of India's (GOI) Indian Department of Biotechnology (DBT), and the Indian Council of Medical Research (ICMR) to establish a consortium of TB cohorts in India under the umbrella of the Indo-U.S. Vaccine Action Program (VAP). Each team within the consortia maintains an observational cohort(s) of TB patients and their contacts with associated scientific objectives ranging from biomarkers studies to understanding the impact of comorbidities in these populations. The results of such research efforts will significantly impact and inform the clinical care of people living with HIV (PLWH) with TB co-infection. Each RePORT consortium is designed to support in-country data collection, specimen biorepositories, and associated research with the goal of adding additional regional consortia to encourage worldwide TB (drug-susceptible and drug-resistant) prevention and treatment research.

《印度报告》是美国国立卫生研究院/艾滋病司(DAIDS)、美国国立卫生研究院/OAR和印度政府(GOI)印度生物技术部门(DBT)以及印度医学研究委员会(ICMR)共同资助的项目，目的是在印美疫苗行动计划(VAP)的框架下在印度建立一个结核病队列联盟。该联盟内的每个团队都维持着一个结核病患者观察队列(S)，以及他们与相关科学目标的接触，范围从生物标记物研究到了解这些人群中合并症的影响。这些研究工作的结果将对艾滋病毒携带者(PLWH)合并感染结核病的临床护理产生重大影响，并为其提供信息。每个报告联合体旨在支持国内数据收集、标本生物库和相关研究，目的是增加更多的区域联合体，以鼓励世界范围内的结核病(药物敏感和耐药)预防和治疗研究。