CSHL 2021 Mechanisms of Metabolic Signaling Conference

CSHL 2021代谢信号机制会议

• 批准号: 10225030
• 负责人: DAVID J. STEWART
• 金额: $ 1.5万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-11 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10225030
• 关键词: Area; Atmosphere; Biochemistry; Blood Circulation; COVID-19 pandemic; Cardiovascular Diseases; Cells; Clinical; Collaborations; Country; Data; Development; Diabetes Mellitus; Discipline; Disease; Emerging Technologies; Ensure; Environment; Equilibrium; Event; Faculty; Fostering; Future; Gender; Genome; Goals; Homeostasis; Hormones; Industrialization; Institution; International; Laboratories; Lead; Length of Stay; Life; Malignant Neoplasms; Mammals; Metabolic; Metabolic Control; Metabolic Diseases; Metabolic Pathway; Metabolism; Methodology; Molecular Biology; Mutation; Neuroglia; Nutrient; Obesity; Oral; Organism; Participant; Pathway interactions; Persons; Physiology; Play; Postdoctoral Fellow; Process; Proliferating; Published Comment; Reagent; Regulation; Research; Research Personnel; Role; Running; Schedule; Scientist; Signal Transduction; System; Technology; Time; Travel; Work; cancer cell; cell type; climate change; environmental change; epigenome; field study; graduate student; innovation; insight; interdisciplinary approach; interest; laboratory facility; meetings; metabolic abnormality assessment; novel; pandemic disease; posters; preference; symposium; unpublished works; virtual

Cold Spring Harbor Laboratory Conference on Mechanisms of Metabolic Signaling May 18 – 22, 2021 Project Summary This proposal seeks support for the meeting on “Mechanisms of Metabolic Signaling” to be held at Cold Spring Harbor Laboratory in May 18 - 22, 2021. The meeting will assemble leaders in the field, together with junior faculty, postdoctoral fellows and graduate students, to discuss the latest advances in our understanding of metabolic regulation and its role in normal physiology as well as a variety of disease states ranging from obesity to cancer. Metabolic processes are required for life, and are remarkably similar from organism to organism and from cell to cell. In mammals, specific cell types use metabolic pathways in highly specialized ways to conduct their cell-specific functions. Further, the specialized function of some cell types serves to maintain metabolic homeostasis of the, multicellular organism by regulating levels of hormone and metabolite messengers in the bloodstream. Metabolic diseases such as obesity and diabetes result when those processes fail. At the same time, cancer is increasingly recognized as a state whereby the malignant cell proliferates by altering its fuel metabolism and ignoring metabolic signals. The meeting will cover a broad spectrum of topics ranging from Metabolic Crosstalk with Genome and Epigenome to Interorgan Crosstalk and Nutrient Utilization. In addition, one session is dedicated to Emerging Technologies in the field. Each session will be chaired by a leading scientist in the field. Oral presentations will be given by a group of distinguished invited speakers as well as speakers selected from submitted abstracts. Selected speakers will include graduate students, postdoctoral fellows and junior faculty aiming for maximal inclusion of young investigators. Of special importance are the two poster sessions, where many participants can present their work in an atmosphere conducive to informal discussion. The meeting will be of moderate size, and we expect about 250 people to attend, the vast majority of whom will be presenting a poster or talk. In the event that the COVID19 pandemic situation is still ongoing in spring 2021, we will plan to run the meeting as a virtual event. CSHL has begun very successfully holding virtual meetings, with the virtual glia meeting for example attracting 1,125 attendees. Even if the meeting is able to be held in person, we will consider having a virtual audience layered on top of the in person attendance. This will be important both because travel concerns are likely to persist for some time after the pandemic, and because, looking to the future, virtual attendance at meetings will help to reduce the effects of scientific conferences on climate change and enable more equitable participation from labs around the world.

冷泉港实验室会议 代谢信号转导机制 2021年5月18日至22日 项目摘要 这项提议寻求支持关于“代谢信号传递机制”的会议 于2021年5月18日至22日在冷泉港实验室举行。这次会议将召集各国领导人 在现场，与初级教师、博士后研究员和研究生一起讨论 代谢调节及其在正常代谢中作用的最新研究进展 生理学以及从肥胖到癌症的各种疾病状态。 新陈代谢过程是生命所必需的，而且从一个生物体到另一个生物体都非常相似 从一个细胞到另一个细胞。在哺乳动物中，特定类型的细胞高度利用代谢途径 以特殊的方式执行其细胞特有的功能。此外，它的专门功能是 某些类型的细胞通过以下方式维持多细胞生物体的代谢动态平衡 调节血液中激素和代谢物信使的水平。新陈代谢 当这些过程失败时，就会导致肥胖和糖尿病等疾病。同时， 癌症日益被认为是一种恶性细胞通过改变而增殖的状态 它的燃料代谢和忽略新陈代谢信号。 会议将涵盖广泛的主题，从新陈代谢相声和 基因组和表观基因组对器官间串扰和养分利用的影响此外，还有一项 会议致力于该领域的新兴技术。每届会议将由一名 该领域的顶尖科学家。口头报告将由一组杰出的应邀嘉宾 发言者以及从提交的摘要中选出的发言者。选定的演讲者将包括 研究生、博士后研究员和初级教职员工的目标是最大限度地纳入年轻人 调查人员。特别重要的是两个海报会议，在那里许多参与者可以 在有利于非正式讨论的气氛中介绍他们的工作。会议将于 中等规模，我们预计将有大约250人参加，其中绝大多数将是 展示海报或演讲。如果COVID19大流行的情况仍在#年进行 2021年春季，我们将计划将会议作为虚拟活动来举办。CSHL已经非常开始了 成功地举办了虚拟会议，例如，虚拟Glia会议吸引了1125人 出席者。即使会议能够亲自举行，我们也会考虑举行一次虚拟的 观众层层叠加在面对面的出席人数之上。这一点很重要，因为旅行 在大流行之后，人们的担忧可能会持续一段时间，因为 未来，虚拟出席会议将有助于减少科学会议对 气候变化，并使世界各地的实验室能够更公平地参与。