Fostering diversity in the next generation of HIV researchers to improve the HIV continuum of care

项目总结。意义重大。在实现联合国艾滋病规划署90-90-90目标方面取得了重大进展 在世界范围内，艾滋病毒预防的新方法正在开始缩小流行病的规模。 然而，在艾滋病毒连续护理方面仍有许多工作要做。艾滋病毒之间的种族和民族多样性 研究人员将在开发新方法以解决目前尚不能解决的“10-10-10”差距方面发挥关键作用 迄今为止进行的最好的行为科学。然而，在医疗/公共领域代表不足的人的资金率 健康(URM)研究人员远低于白人研究人员(约15%对25%)，只有6%的K 职业发展奖的申请者是URM实习生。接近。在目标1中，拟议的养育 艾滋病研究项目的多样性将遵循社会认知职业理论和指导 不同的框架，以培训导师的关键技能，以成功地支持URM学员。工作坊将是 每年举行一次，每季度增加一次会议。在目标2中，该方案将提供结构化研究 专门为URM受训人员提供指导，以解决艾滋病毒持续护理问题。将确定受训人员的身份 通过麻省总医院的住院医师和博士后奖学金计划(科室 医学、传染病、精神病学、产科/妇科学)以及硕士和博士课程 哈佛大学公共卫生学院(行为和社会科学系，全球卫生 和人口、流行病学、免疫学和传染病)；招募还将包括积极的 外展工作。受训人员将接受有关艾滋病毒护理和职业发展连续体系的正式教学， 重点关注与URM学员特别相关的问题(例如，隐性偏见)。导师将支持URM 受训人员获得有关行为艾滋病毒研究的知识，并提供实践技术和 发展成功的研究事业所需的专业技能。所有活动都将根据以下需要量身定做 URM和每个人的训练阶段。研究将涉及艾滋病毒连续体的以下领域 国内和全球的护理：准备工作和坚持；艾滋病毒检测和外展；联系； 保留护理和坚持抗逆转录病毒疗法；慢性护理和治疗艾滋病毒的并发症；孕产妇健康和 围产期传播。该计划的主要成果将是艾滋病毒研究导师与必要的 指导能力，以成功地支持URM学员，以及高质量、令人满意的和 对具备核心研究能力的URM学员进行有影响力的指导。其他结果包括 学员奖学金(即手稿和助学金)，学员在学术研究中的进步 流水线，以及程序执行的保真度。创新。艾滋病毒研究计划中的多样性培育 在1)有针对性地培训导师以有效支持URM学员方面具有创新性，2)专注于过渡 许多受训人员离开学术研究的时期，3)创建一个基础广泛的实践社区 在URM学员中，以及4)跨学科关注，促进交叉协作和团队科学。

PROJECT SUMMARY. Significance. Great progress has been made toward the UNAIDS 90-90-90 goals worldwide, and novel methods for HIV prevention are beginning to decrease the size of the epidemic. However, much work on the HIV continuum of care remains. Racial and ethnic diversity among HIV researchers will be critical in developing new approaches to address the “10-10-10” gap that currently eludes the best behavioral science conducted to date. Yet, funding rates for underrepresented in medicine/public health (URM) researchers are well below those of white researchers (~15% versus 25%) and only 6% of K career development award applicants have been URM trainees. Approach. In Aim 1, the proposed Fostering Diversity in HIV Research Program will follow Social Cognitive Career Theory and the Mentoring Across Difference framework to train mentors in key skills to successfully support URM trainees. Workshops will be held annually with additional quarterly sessions. In Aim 2, the program will provide structured research mentorship exclusively to URM trainees to address the HIV continuum of care. Trainees will be identified through residency and post-doctoral fellowship programs at Massachusetts General Hospital (Departments of Medicine, Infectious Disease, Psychiatry, Obstetrics/Gynecology) and master’s degree and PhD programs at the Harvard T. H. Chan School of Public Health (Departments of Behavioral and Social Science, Global Health and Population, Epidemiology, Immunology and Infectious Diseases); recruitment will also involve active outreach efforts. Trainees will receive formal didactics on the HIV continuum of care and career development, focusing on issues particularly relevant for URM trainees (e.g., implicit bias). Mentors will support URM trainees in gaining knowledge about behavioral HIV research, as well as provide the hands-on technical and professional skills needed to develop successful research careers. All activities will be tailored to the needs of URMs and each individual’s stage of training. Research will address the following areas of the HIV continuum of care both domestically and globally: PrEP delivery and adherence; HIV testing and outreach; linkage, retention in care, and ART adherence; chronic care and complications of treated HIV; maternal health and perinatal transmission. Primary outcomes of the program will be HIV research mentors with the necessary mentoring competencies to successfully support URM trainees, as well as high quality, satisfying, and impactful mentorship of URM trainees who achieve core research competencies. Other outcomes include trainee scholarship (i.e., manuscripts and grants), progression of trainees through the academic research pipeline, and fidelity of program implementation. Innovation. The Fostering Diversity in HIV Research Program is innovative in its 1) targeted training of mentors to effective support URM trainees, 2) focus on the transition periods when many trainees leave academic research, 3) creation of a broad-based Community of Practice among URM trainees, and 4) interdisciplinary focus, fostering cross-collaboration and team science.