2021 Cell Biology of Metals Gordon Research Conference and Seminar

项目摘要 戈登研究会议（GRC）和戈登研究研讨会（GRS）系列的细胞生物学， 金属通常汇集了一个新的和建立的研究科学家和 医生分享和讨论在金属稳态领域的最新突破。作为基石 在这个迅速扩大的领域的会议，两年一度的金属GRC细胞生物学有一个忠实的追随者，因为 2005年成立，一直吸引140至180名与会者。由于参加的需求很大， 本次会议，伴随的GRS于2017年启动，以提供额外的演讲和网络 为该领域的研究生和博士后研究人员提供机会。戈登研究会议 是国际知名的高品质，这些会议的前沿性质，展示新的 未发表的工作;拟议的2021年金属细胞生物学会议的计划努力保持 这个高标准。 该系列会议的第九次迭代将涵盖从遗传学， 生物化学，结构生物学和无机化学，生物信息学，微生物发病机制和临床 药会议的主题将集中在收购，贩运，监管和动态利用的金属， 从微生物到人类的蛋白质、细胞、组织和生物体，以及金属在生理学、疾病、 和宿主-病原体相互作用。此外，用于监测、量化和 将分享和讨论细胞和组织中的金属可视化。会议形式，包括基调 演示文稿，初级和高级研究人员的研究会谈，海报会谈，海报会议和非正式会议 科学讨论，促进开放的沟通，有效的指导和跨学科合作 为新的和既定的调查人员和学员，将维持健康的增长和多样化，这 关键和迅速扩大的领域。由于金属的获取和体内平衡强烈影响人类健康， 疾病以及微生物发病机制，本次会议系列的最终目标是揭示 功能失调的金属代谢的病理机制，以便将这些发现转化为尖端的 金属相关疾病和病症的诊断方法和治疗方法。

PROJECT SUMMARY The Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) series on the Cell Biology of Metals routinely brings together an exceptional community of new and established research scientists and physicians to share and discuss the latest breakthroughs in the field of metal homeostasis. As a cornerstone conference in this rapidly expanding field, the biennial Cell Biology of Metals GRC has had a loyal following since its inception in 2005, consistently attracting between 140 and 180 attendees. Due to the high demand to attend this conference, the accompanying GRS was initiated in 2017 to provide additional speaking and networking opportunities for graduate students and postdoctoral researchers in this field. Gordon Research Conferences are internationally renowned for the high-quality, cutting edge nature of these meetings that showcase new unpublished work; the program of the proposed 2021 Cell Biology of Metals conference endeavors to maintain this high standard. The 9th iteration of this conference series will span a diverse range of scientific interests from genetics, biochemistry, structural biology, and inorganic chemistry, to bioinformatics, microbial pathogenesis, and clinical medicine. Session topics will focus on the acquisition, trafficking, regulation, and dynamic utilization of metals in proteins, cells, tissues, and organisms from microbes to humans, and the role of metals in physiology, disease, and host-pathogen interactions. In addition, novel techniques and tools for monitoring, quantifying, and visualizing metals in cells and tissues will be shared and discussed. The conference format, including keynote presentations, research talks from junior and senior investigators, poster talks, poster sessions, and informal scientific discussions, promotes open communication, effective mentoring, and cross-discipline collaborations for new and established investigators and trainees that will sustain the healthy growth and diversification of this critical and rapidly expanding field. Since metal acquisition and homeostasis strongly impacts human health and disease as well as microbial pathogenesis, the ultimate goal of this conference series is to uncover the pathological mechanisms of dysfunctional metal metabolism in order to translate these findings into cutting-edge diagnostic approaches and therapeutic treatments for metal-related diseases and disorders.