National Cancer Institute (NCI) Cancer ClinicalInvestigator Team Leadership Award (CCITLA) P30 Administrative Supplement forFiscal Year (FY) 2021
美国国家癌症研究所 (NCI) 癌症临床研究者团队领导奖 (CCITLA) P30 2021 财年 (FY) 行政补充文件
基本信息
- 批准号:10326465
- 负责人:
- 金额:$ 5.29万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2008
- 资助国家:美国
- 起止时间:2008-08-08 至 2026-08-31
- 项目状态:未结题
- 来源:
- 关键词:Administrative SupplementAffectAsiansAwardBaltimoreBasic ScienceBehaviorBiologyBiometryCancer BiologyCancer CenterCancer Center Support GrantCancer Grant Supplements (P30)Cancer PatientCatchment AreaCigaretteCitiesClinicClinicalClinical ResearchClinical TrialsCommunitiesComprehensive Cancer CenterCountyDentistryDetectionDiscipline of NursingDoctor of MedicineFacultyFirst Independent Research Support and Transition AwardsFlow CytometryFundingFutureGenomicsHead CancerHumanImageInstitutesInvestigational TherapiesInvestmentsLaboratoriesLeadershipMalignant NeoplasmsMalignant neoplasm of lungMalignant neoplasm of prostateMarylandMedicalMedical centerMiddle School StudentMinorityMinority GroupsMissionMolecularMolecular BiologyNamesNational Cancer InstituteNeck CancerParticipantPathologyPatient CarePatientsPharmacy SchoolsPharmacy facilityPopulationPopulation ResearchPopulation SciencesPositioning AttributePreventionPrevention ResearchPrevention strategyPublic Health SchoolsReportingResearchResearch ActivityResearch DesignResearch PersonnelSchool DentistrySchool NursingSchoolsScreening for cancerServicesStructureStudentsSystemTalentsTherapeuticTherapeutic TrialsTrainingTranslational ResearchTranslationsUnderrepresented MinorityUniversitiesWorkacronymsanticancer researchbiobankcancer carecancer health disparitycancer therapyclinical careclinical phenotypeclinically relevantcollegecommunity based researchdesignfundamental researchhealth disparityhormone related cancerinnovationmedical schoolsmemberminority communitiesmortalitymultidisciplinaryneoplasm immunotherapynewspreventprogramsracial and ethnicracial diversityscience educationstandard of carestructural biologytumor immunologytumor registryvirology
项目摘要
1.0 Abstract: Overall
Our strategy at the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center
(UMGCCC) is to take advantage of discoveries in basic cancer biology, in conjunction with clinical, population,
and prevention research, to (a) develop and apply innovative therapeutic and preventive strategies to cancer
patients, (b) describe the molecular mechanisms involving specific clinical phenotypes and behaviors, (c) apply
discoveries and strategies to the Maryland community with a specific focus on cancer disparities, and (d) provide
training in cancer biology and cancer care for students, fellows, clinicians, and staff. These strategies collectively
will serve the clinical and research missions of the Cancer Center for the Maryland community well into the
future. In this application, UMGCCC seeks the second competitive renewal of the Cancer Center Support Grant
(CCSG), which was first awarded to UMGCCC in August 2008; “Comprehensive” designation was awarded in
2016. For this application, UMGCCC is represented by 137 full and 88 associate members working in 5 research
programs, unchanged since our 2015 application. The application describes seven shared services. UMGCCC
provides an effective structure to support the multidisciplinary cancer research activities of this talented group of
investigators. Total direct cancer funding is $79.1 million, with $14.2 million from the National Cancer Institute.
Direct cancer funding has increased 70 percent in the last cycle. In 2019, UMGCCC served 3,095 new cancer
patients. In the last funding cycle, a total of 9,702 patients participated in clinical trials. Fifty-six percent of all
participants in clinical trials were minorities, reflecting UMGCCC's unique position and mission to involve the
minority community in state-of-the-art clinical and translational research. This includes 48.2 percent
underrepresented minorities as well as 7.8 percent Asians, the latter reflecting clinical trials examining health
disparities in that group. Underrepresented minority accrual to therapeutic trials is 34.7 percent. UMGCCC
continues to make outstanding contributions to understanding cancer biology, and important recent work from
UMGCCC labs and clinics is now the standard of care or in advanced clinical trials. The U.S. News & World
Report ranking of U.S. cancer programs has named UMGCCC in the top 50 for 13 consecutive years. Reflecting
remarkable and continued progress, UMGCCC seeks to renew its CCSG to enhance and expand its efforts and
support high-quality and clinically relevant cancer research.
1.0摘要:总体而言
我们在马里兰州大学玛琳和斯图尔特格林鲍姆综合癌症中心的策略
(UMGCCC)是利用基础癌症生物学的发现,结合临床,人口,
和预防研究,以(a)制定和应用创新的治疗和预防癌症的战略,
患者,(B)描述涉及特定临床表型和行为的分子机制,(c)应用
发现和战略,以马里兰州社区与癌症的差异,具体重点,和(d)提供
为学生、研究员、临床医生和工作人员提供癌症生物学和癌症护理培训。这些战略共同
将为马里兰州社区癌症中心的临床和研究任务服务,
未来在此申请中,UMGCCC寻求癌症中心支持补助金的第二次竞争性更新
(CCSG),于2008年8月首次授予UMGCCC;
2016.在这项申请中,UMGCCC由137名正式成员和88名准成员代表,他们在5个研究领域工作
自2015年申请以来,我们的计划没有变化。该应用程序描述了七个共享服务。UMGCCC
提供了一个有效的结构,以支持这一人才群体的多学科癌症研究活动,
investigators.直接癌症资金总额为7910万美元,其中1420万美元来自国家癌症研究所。
直接癌症资金在上一个周期增加了70%。2019年,UMGCCC为3,095名新癌症患者提供服务
患者在上一个资助周期,共有9,702名患者参加了临床试验。五十六成
临床试验的参与者是少数民族,反映了UMGCCC的独特地位和使命,
少数民族社区在国家的最先进的临床和转化研究。其中,48.2%
代表性不足的少数民族以及7.8%的亚洲人,后者反映了检查健康状况的临床试验
这个群体的差距。治疗性试验中代表性不足的少数族裔占34.7%。UMGCCC
继续为理解癌症生物学做出杰出贡献,
UMGCCC实验室和诊所现在是护理标准或先进的临床试验。美国新闻与世界
美国癌症项目的报告排名连续13年将UMGCCC评为前50名。反映
取得了显著和持续的进展,UMGCCC寻求更新其CCSG,以加强和扩大其努力,
支持高质量和临床相关的癌症研究。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
KEVIN J. CULLEN其他文献
KEVIN J. CULLEN的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('KEVIN J. CULLEN', 18)}}的其他基金
Targeting PI3Kalpha beta and the ErbB family of protein-tyrosine kinases in cisplatin-resistant head and neck squamous cell carcinomas (HNSCC)
靶向 PI3Kalpha beta 和 ErbB 蛋白酪氨酸激酶家族治疗顺铂耐药的头颈鳞状细胞癌 (HNSCC)
- 批准号:
10667253 - 财政年份:2022
- 资助金额:
$ 5.29万 - 项目类别:
相似海外基金
RII Track-4:NSF: From the Ground Up to the Air Above Coastal Dunes: How Groundwater and Evaporation Affect the Mechanism of Wind Erosion
RII Track-4:NSF:从地面到沿海沙丘上方的空气:地下水和蒸发如何影响风蚀机制
- 批准号:
2327346 - 财政年份:2024
- 资助金额:
$ 5.29万 - 项目类别:
Standard Grant
BRC-BIO: Establishing Astrangia poculata as a study system to understand how multi-partner symbiotic interactions affect pathogen response in cnidarians
BRC-BIO:建立 Astrangia poculata 作为研究系统,以了解多伙伴共生相互作用如何影响刺胞动物的病原体反应
- 批准号:
2312555 - 财政年份:2024
- 资助金额:
$ 5.29万 - 项目类别:
Standard Grant
How Does Particle Material Properties Insoluble and Partially Soluble Affect Sensory Perception Of Fat based Products
不溶性和部分可溶的颗粒材料特性如何影响脂肪基产品的感官知觉
- 批准号:
BB/Z514391/1 - 财政年份:2024
- 资助金额:
$ 5.29万 - 项目类别:
Training Grant
Graduating in Austerity: Do Welfare Cuts Affect the Career Path of University Students?
紧缩毕业:福利削减会影响大学生的职业道路吗?
- 批准号:
ES/Z502595/1 - 财政年份:2024
- 资助金额:
$ 5.29万 - 项目类别:
Fellowship
Insecure lives and the policy disconnect: How multiple insecurities affect Levelling Up and what joined-up policy can do to help
不安全的生活和政策脱节:多种不安全因素如何影响升级以及联合政策可以提供哪些帮助
- 批准号:
ES/Z000149/1 - 财政年份:2024
- 资助金额:
$ 5.29万 - 项目类别:
Research Grant
感性個人差指標 Affect-X の構築とビスポークAIサービスの基盤確立
建立个人敏感度指数 Affect-X 并为定制人工智能服务奠定基础
- 批准号:
23K24936 - 财政年份:2024
- 资助金额:
$ 5.29万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
How does metal binding affect the function of proteins targeted by a devastating pathogen of cereal crops?
金属结合如何影响谷类作物毁灭性病原体靶向的蛋白质的功能?
- 批准号:
2901648 - 财政年份:2024
- 资助金额:
$ 5.29万 - 项目类别:
Studentship
ERI: Developing a Trust-supporting Design Framework with Affect for Human-AI Collaboration
ERI:开发一个支持信任的设计框架,影响人类与人工智能的协作
- 批准号:
2301846 - 财政年份:2023
- 资助金额:
$ 5.29万 - 项目类别:
Standard Grant
Investigating how double-negative T cells affect anti-leukemic and GvHD-inducing activities of conventional T cells
研究双阴性 T 细胞如何影响传统 T 细胞的抗白血病和 GvHD 诱导活性
- 批准号:
488039 - 财政年份:2023
- 资助金额:
$ 5.29万 - 项目类别:
Operating Grants
How motor impairments due to neurodegenerative diseases affect masticatory movements
神经退行性疾病引起的运动障碍如何影响咀嚼运动
- 批准号:
23K16076 - 财政年份:2023
- 资助金额:
$ 5.29万 - 项目类别:
Grant-in-Aid for Early-Career Scientists