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中文摘要
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项目总结(见说明): 马里兰大学马琳和斯图尔特·格林鲍姆癌症中心(UMGCC)的动物共享Sen/ICE是兽医资源的一个组成部分,而兽医资源又是马里兰大学医学院(UMSOM)比较医学服务部门的一部分。动物共享服务占兽医资源公司总动物业务的三分之一以上。共享的使命 服务是为UMGCC成员提供全面的实验动物服务、护理和设施。动物共享服务的目标是提供高质量、广泛的服务,包括动物采购、畜牧业护理、医疗监督、微生物监测、病理服务、转基因和免疫缺陷啮齿动物群体的维护、咨询和合作 体内癌症中心研究项目的动物模型选择和开发,以及管理。 比较医学是一个独立的学术部门,开展合作和独立的研究。它成立于1989年,研究用于生物医学研究的人类疾病动物模型的特征,并使用此类模型来促进对疾病或生物过程的了解。比较医学通过为兽医和工作人员提供协作研究和专业发展,为UMSOM和UMGCC做出贡献,是在研究中使用实验室动物的信息和指导资源。兽医资源和机构护理和使用委员会监督和支持所有在UMSOM使用活动物的生物医学研究项目,包括由UMGCC成员进行的动物研究。密歇根大学的教职员工和学生 UMGCC明白,他们的研究质量在很大程度上取决于实验室动物护理和使用的质量。此外,UMSOM和UMGCC赞助合乎道德和人道的实验室动物护理的保证,加强了整个大学社区对教育和研究使命的赞赏。
英文摘要
PROJECT SUMMARY (See instmctions): The Animal Shared Sen/ice at the University of Maryland Marlene and Stewart Greenebaum Cancer Center (UMGCC) is a component of Veterinary Resources, which in turn, is part of the service arm of Comparative Medicine at the University of Maryland School of Medicine (UMSOM). The Animal Shared Service represents more than one-third of Veterinary Resources' total animal operations. The mission of the shared service is to provide comprehensive lab animal services, care, and facilities to members of UMGCC . The goals of the Animal Shared Service are to provide high-quality, extensive services¿including animal procurement, husbandry care, medical oversight, microbiological monitoring, pathology services, maintenance of genetically altered and immunodeficient rodent colonies, consultation and collaboration on animal model selection and development, and management of in vivo cancer center research projects. Comparative Medicine is an independent academic division that conducts collaborative and independent research. Established in 1989, it studies the characterization of animal models of human disease for biomedical research and the use of such models to advance understanding of disease or biological processes. Comparative Medicine contributes to UMSOM and UMGCC by providing collaborative research and professional development of veterinary physicians and staff, and is a resource for information and instruction on the use of lab animals in research. Veterinary Resources and the Institutional Care and Use Committee oversee and support all biomedical research projects that use live animals at UMSOM, including animal research carried out by members of UMGCC. The faculty, staff, and students at UMSOM and UMGCC understand that the quality of their research is critically dependant on the quality of lab animal care and use. Furthermore, appreciation of the educational and research missions by the university community at large is enhanced by the assurance that UMSOM and UMGCC sponsor ethical and humane lab animal care.
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Targeting PI3Kalpha beta and the ErbB family of protein-tyrosine kinases in cisplatin-resistant head and neck squamous cell carcinomas (HNSCC)
  • 批准号:
    10667253
  • 项目类别:
  • 资助金额:
    $37.63万
  • 财政年份:
    2022
  • 负责人:
    KEVIN J. CULLEN
  • 依托单位:
Cancer Center Administration
  • 批准号:
    8711298
  • 项目类别:
  • 资助金额:
    $9.74万
  • 财政年份:
    2014
  • 负责人:
    KEVIN J. CULLEN
  • 依托单位:
Program Leaders of Research Programs
  • 批准号:
    8711295
  • 项目类别:
  • 资助金额:
    $8.21万
  • 财政年份:
    2014
  • 负责人:
    KEVIN J. CULLEN
  • 依托单位:
Program Leaders
  • 批准号:
    8340231
  • 项目类别:
  • 资助金额:
    $8.47万
  • 财政年份:
    2011
  • 负责人:
    KEVIN J. CULLEN
  • 依托单位:
海外基金