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Human and Animal Imaging Core

人类和动物成像核心

基本信息

批准号：
10454195
负责人：
WILLIAM Davis GAILLARD
金额：
$ 25.55万
依托单位：
CHILDREN'S RESEARCH INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-07-21 至 2026-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10454195
关键词：
Affect Algorithms Anatomy Animal Model Animals Biochemical Bioinformatics Biological Markers Brain Brain Diseases Brain Injuries Brain imaging Cells Child Clinical Clinical Research Cognitive Collaborations Computer software Development Discipline Disease Disease model District of Columbia Dyslexia Education Epilepsy Evaluation Faculty Fostering Functional Imaging Genomics Hospitals Human Human Resources Image Imaging Device Imaging Techniques Imaging technology Inborn Errors of Metabolism Individual Infant Infrastructure Injury Inpatients Institution Intellectual and Developmental Disabilities Research Centers Intervention Investments Laboratories Learning Machine Learning Magnetic Resonance Imaging Measurement Methods Microscopy Mission Molecular Monitor Motion Neonatal Neuronal Plasticity Outcome Pathway Analysis Performance Play Population Positron-Emission Tomography Protocols documentation Quality Control Research Research Personnel Research Project Grants Resources Risk Role Sequence Analysis Services Site Structure Supervision Targeted Research Technical Expertise Techniques Technology Time Tissues Training Training Support Universities Work analytical method animal imaging autism spectrum disorder base career congenital heart disorder cost cost effective data integrity data standards design fetal flexibility human imaging human model hypoxic ischemic injury imaging facilities imaging modality improved in vivo innovation instrument instrumentation magnetic field molecular imaging neonate neural circuit neurobehavioral neuroimaging neuroprotection novel novel imaging technology perinatal stroke pre-clinical preclinical study relating to nervous system response single photon emission computed tomography skills spectroscopic imaging

项目摘要

Abstract The Human and Animal Imaging Core (HAIC) provides access to state-of-the-art in vivo whole brain imaging technologies to DC-IDDRC investigators in order to support, facilitate, and enhance IDD-targeted research in humans and in animal models. To achieve the Core’s aims we have established advanced imaging facilities at three collaborating DC-IDDRC institutions - Howard University (HU), Georgetown University (GU), and Children’s National Hospital (CNH) - that provide structural and functional imaging of animal models and human populations. The HAIC provides access to a wide array of imaging tools to investigate mechanisms of disease, establish biomarkers, examine effects of disease, and monitor outcomes of interventions. We have made significant institutional investments in 3T human MRI scanners at CNH, and GU that provide researchers with state-of-the-art imaging instrumentation and expand our imaging capacity in neonates and ill children. Furthermore, we have also invested in MRI scanner/software upgrades and added PET, SPECT, and CT to the preclinical animal imaging facilities at HU. HAIC personnel provide technical expertise in imaging strategy design, essential imaging services, acquisition and innovative imaging sequences and analysis methods across all sites and institutions. Core faculty and staff also help educate, train, and support investigators in the use of advanced neuroimaging methods, applications, and analysis software as well as foster innovation. The HAIC works synergistically, and fosters collaborations, with other DC-IDDRC cores including the Neurobehavioral Evaluation, the Cell and Tissue Microscopy Core, the Genomics and Bioinformatics Core, and Clinical Translational Cores, and supports the P50 Research Project. Our administrative structure provides the quality control necessary for the integrity of a smoothly functioning core to achieve the DC-IDDRC mission.

摘要