Research Training in Anesthesia

麻醉研究培训

• 批准号: 10642668
• 负责人: ROBERT SCHONBERGER
• 金额: $ 19.89万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10642668
• 关键词: Anesthesia procedures; Research Training

Abstract Anesthesiology research has grown well beyond a search for drug mechanisms of action. The expertise of anesthesiologists now extends to all aspects of preoperative care. This competing renewal has been written with that in mind. It is our intention to provide talented and dedicated individuals with adequate time to delve into cutting edge research under the guidance of highly successful mentors. Dr. Niklason has served as the Program Director for this T32 Training Program for the past 9 years. Dr. Niklason will continue in this role for the upcoming competing renewal, and will be joined in the leadership effort by Dr. Helene Benveniste, Professor of Anesthesiology at Yale. Dr. Benveniste will serve as co-Director on this proposal. Our post-doctoral training program continues to employ 5 tracks: Neurobiology, Vascular Biology, Immunology/Inflammation, Bioengineering, and Clinical Research. Of these tracks, trainees have most commonly sought Neurobiology, Clinical Research, and Bioengineering. In this renewal as in previous incarnations of the program, all trainees will be involved full-time, 40 hours per week, in research training, whether it be laboratory research, didactic training, preparing manuscripts and grants, or attending meetings and conferences. The five training tracks are designed to provide trainees with a breadth of basic science and clinical research opportunities, in areas that are directly relevant to anesthetic practice. Preceptors have been strategically selected, and have the following qualities: i) history of outstanding training and mentorship – for younger Preceptors, a history of excellent interactions with junior house staff and an exciting and clinically relevant research program are deemed sufficient for inclusion; ii) research focus in one or more of the five selected training tracks; iii) clear desire to train productive clinician scientists in Anesthesia. Commonly, Preceptors having expertise across multiple scientific areas can provide a richer and more interdisciplinary training experience, which will be profoundly beneficial to trainees after they emerge from the T32 program to begin independent careers. Adding to the integration of the T32 program, we have instituted regular scientific and social meetings for all trainees, so that they may share scientific as well as career development experiences. To date, we have been extremely pleased with the progress of our current and former trainees, and hope that the NIGMS will continue to support this remarkably successful program.

摘要

项目成果

Neuronal adhesion and synapse organization in recovery after brain injury.

• DOI: 10.2217/fnl.13.35
• 发表时间: 2013-09
• 期刊: Future neurology
• 影响因子: 1.3
• 作者: Park K;Biederer T
• 通讯作者: Biederer T

SARS-CoV-2 leverages airway epithelial protective mechanism for viral infection.

• DOI: 10.1016/j.isci.2023.106175
• 发表时间: 2023-03-17
• 期刊: ISCIENCE
• 影响因子: 5.8
• 作者: Greaney, Allison Marie;Raredon, Micha Sam Brickman;Kochugaeva, Maria P.;Niklason, Laura E.;Levchenko, Andre
• 通讯作者: Levchenko, Andre

Mesenchymal stromal cells form vascular tubes when placed in fibrin sealant and accelerate wound healing in vivo.

• DOI: 10.1016/j.biomaterials.2014.11.011
• 发表时间: 2015-02
• 期刊: BIOMATERIALS
• 影响因子: 14
• 作者: Mendez, Julio J.;Ghaedi, Mahboobe;Sivarapatna, Amogh;Dimitrievska, Sashka;Shao, Zhen;Osuji, Chinedum O.;Steinbacher, Derek M.;Leffell, David J.;Niklason, Laura E.
• 通讯作者: Niklason, Laura E.

Inhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy.

• DOI: 10.1016/j.yebeh.2015.07.015
• 发表时间: 2015-10
• 期刊: Epilepsy & behavior : E&B
• 作者: Gruenbaum SE;Wang H;Zaveri HP;Tang AB;Lee TS;Eid T;Dhaher R
• 通讯作者: Dhaher R

Association between Hypophosphatemia and Cardiac Arrhythmias in the Early Stage of Sepsis: Could Phosphorus Replacement Treatment Reduce the Incidence of Arrhythmias?

脓毒症早期低磷血症与心律失常之间的关联：磷替代治疗能否降低心律失常的发生率？

• DOI: 10.5049/ebp.2014.12.1.19
• 发表时间: 2014
• 期刊: Electrolyte & blood pressure : E & BP
• 作者: Schwartz,Andrei;Brotfain,Evgeni;Koyfman,Leonid;Kutz,Ruslan;Gruenbaum,ShaunE;Klein,Moti;Zlotnik,Alexander
• 通讯作者: Zlotnik,Alexander