FAIR DOs: Findable, Accessible, Interoperable, Reusable Development of Open Simulation

FAIR DO：可查找、可访问、可互操作、可重用的开放模拟开发

• 批准号: 10523857
• 负责人: Walter F Boron
• 金额: $ 13.04万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10523857
• 关键词: Arts; Autonomic nervous system; Award; Basic Science; Biomedical Engineering; Biophysics; Body Surface; Boron; British; California; Clinic; Computer Models; Data; Data Set; Department chair; Development; Doctor of Philosophy; Ecosystem; Educational process of instructing; Engineering; Ensure; Enteric Nervous System; Epithelial; Epithelial Cells; FAIR principles; Faculty; Feedback; Fostering; Future; Gastrointestinal tract structure; Hour; Information Networks; Infrastructure; Institution; International; Journals; Kidney; Knowledge; Knowledge Management; Leadership; Link; Literature; Maps; Marketing; Master of Science; Medical; Medical Students; Mentors; Methodology; Methods; Modeling; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Nervous System Physiology; Neurobiology; Outcome; Paper; Peer Review; Physiological; Physiological Processes; Physiology; Population; Publications; Publishing; Reproducibility; Research; Research Personnel; Research Project Grants; Resources; Schools; Science; Seasons; Site; Standardization; Structure; Student recruitment; Students; Supervision; Surface; System; Testing; Textbooks; Training; Transport Process; Universities; Validation; Work; base; college; computerized tools; data resource; data sharing; education research; education resources; experience; gastrointestinal; infrastructure development; lectures; mathematical model; medical schools; meter; models and simulation; neuroregulation; next generation; open data; programs; recruit; renal epithelium; response; simulation

PROJECT SUMMARY FAIR DOs (Findable, Accessible, Interoperable, Reusable: Development Of Simulations) is a 5-year research education program in the modeling and simulation of digestive and renal neurobiology. It is developed by a team of award-winning faculty of educators and researchers who, among other things, is behind the FAIR mapping and knowledge management infrastructure for the SPARC effort. The main thrust of FAIR DOs is to educate the next generation of researchers and clinicians in the neural regulation of digestive and renal epithelia through taught modules and supervised modeling projects that make use of SPARC datasets, maps, and models. The FAIR DOs faculty will leverage teaching structures at Case Western Reserve University to recruit students. Overall, FAIR DOs aims to provide about 35/45 hours of training to over 75 students over the proposed five-year project, with each student research project producing one publication in the Physiome journal--launched by the International Union of Physiological Sciences. The SPARC Portal will provide findability to these student- generated open-access models and associated data via its Search and Flatmaps functions, as well as accessible interactivity via the O2S2PARC simulation platform. Overall, the FAIR DOs effort will provide a unique educational, mentored experience that will also generate a SPARC ecosystem of interoperating models that coherently study the neurobiology of digestive and renal epithelial transport. From a didactic “Systems” perspective, this ecosystem of models will be organized to follow the teaching narrative of the British Medical Association Award-winning “Medical Physiology 3rd Ed.” textbook, supplemented with recent literature, setting the stage to further leverage SPARC resources for education in the future.

项目概要 FAIR DOs（可查找、可访问、可互操作、可重用：模拟开发）是一项为期 5 年的研究 消化和肾脏神经生物学建模和模拟的教育计划。它是由一个团队开发的 由屡获殊荣的教育工作者和研究人员组成，他们是 FAIR 绘图的幕后推手 SPARC 工作的知识管理基础设施。 FAIR DO 的主要目标是教育 下一代研究人员和临床医生通过消化和肾上皮细胞的神经调节 教授使用 SPARC 数据集、地图和模型的模块和监督建模项目。这 FAIR DO 教师将利用凯斯西储大学的教学结构来招收学生。 总体而言，FAIR DO 的目标是在拟议的五年内为超过 75 名学生提供约 35/45 小时的培训 项目，每个学生研究项目都会在 Physiome 杂志上发表一份出版物——由 国际生理科学联合会。 SPARC 门户将为这些学生提供可查找性 - 通过其搜索和平面地图功能生成开放访问模型和相关数据，以及可访问的 通过 O2S2PARC 模拟平台进行交互。总体而言，FAIR DOs 的努力将提供独特的 教育和指导经验还将生成互操作模型的 SPARC 生态系统 连贯地研究消化和肾上皮运输的神经生物学。来自说教式的“系统” 从角度来看，这个模型生态系统将按照英国医学的教学叙述进行组织 协会获奖的《医学生理学第三版》。教科书，辅以最新文献、背景 为未来进一步利用SPARC资源进行教育提供舞台。