FAIR DOs: Findable, Accessible, Interoperable, Reusable Development of Open Simulation
FAIR DOs: Findable, Accessible, Interoperable, Reusable Development of Open Simulation
批准号:
10523857
负责人:
Walter F Boron
金额:
$13.04万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-09-20 至 2027-06-30
关键词:
ArtsAutonomic nervous systemAwardBasic ScienceBiomedical EngineeringBiophysicsBody SurfaceBoronBritishCaliforniaClinicComputer ModelsDataData SetDepartment chairDevelopmentDoctor of PhilosophyEcosystemEducational process of instructingEngineeringEnsureEnteric Nervous SystemEpithelialEpithelial CellsFAIR principlesFacultyFeedbackFosteringFutureGastrointestinal tract structureHourInformation NetworksInfrastructureInstitutionInternationalJournalsKidneyKnowledgeKnowledge ManagementLeadershipLinkLiteratureMapsMarketingMaster of ScienceMedicalMedical StudentsMentorsMethodologyMethodsModelingMonitorNational Institute of Diabetes and Digestive and Kidney DiseasesNervous System PhysiologyNeurobiologyOutcomePaperPeer ReviewPhysiologicalPhysiological ProcessesPhysiologyPopulationPublicationsPublishingReproducibilityResearchResearch PersonnelResearch Project GrantsResourcesSchoolsScienceSeasonsSiteStandardizationStructureStudent recruitmentStudentsSupervisionSurfaceSystemTestingTextbooksTrainingTransport ProcessUniversitiesValidationWorkbasecollegecomputerized toolsdata resourcedata sharingeducation researcheducation resourcesexperiencegastrointestinalinfrastructure developmentlecturesmathematical modelmedical schoolsmetermodels and simulationneuroregulationnext generationopen dataprogramsrecruitrenal epitheliumresponsesimulation
中文摘要
项目总结
公平DoS(可查找、可访问、可互操作、可重复使用:模拟的开发)是一个为期5年的研究
消化和肾脏神经生物学的建模和模拟方面的教育计划。它是由一个团队开发的
由获奖的教育工作者和研究人员组成,他们是公平地图的幕后推手
和知识管理基础设施,为SPARC的努力。公平正义的主旨是教育
消化和肾上皮神经调节的下一代研究人员和临床医生
使用SPARC数据集、地图和模型的教学模块和有指导的建模项目。这个
FIRE DOS教职员工将利用凯斯西储大学的教学结构招生。
总体而言,公平竞争司的目标是在拟议的五年内为超过75名学生提供约35/45小时的培训。
项目,每个学生研究项目在Physiome期刊上发表一篇文章--由
国际生理学联合会。SPARC门户将为这些学生提供查找功能-
通过其搜索和平面地图功能生成开放访问模型和相关数据,以及可访问
通过O2S2PARC模拟平台进行交互。总体而言,公平的DoS努力将提供一个独特的
教育、指导体验,还将生成SPARC互操作模型生态系统,
连贯地研究消化和肾上皮运输的神经生物学。来自说教版的《系统》
从视角来看,这个模型生态系统将被组织起来,以遵循英国医学的教学叙事
协会奖获得者《医学生理学第三版》。教科书,辅以最近的文献,背景
这是未来进一步利用SPARC资源用于教育的舞台。
英文摘要
PROJECT SUMMARY
FAIR DOs (Findable, Accessible, Interoperable, Reusable: Development Of Simulations) is a 5-year research
education program in the modeling and simulation of digestive and renal neurobiology. It is developed by a team
of award-winning faculty of educators and researchers who, among other things, is behind the FAIR mapping
and knowledge management infrastructure for the SPARC effort. The main thrust of FAIR DOs is to educate the
next generation of researchers and clinicians in the neural regulation of digestive and renal epithelia through
taught modules and supervised modeling projects that make use of SPARC datasets, maps, and models. The
FAIR DOs faculty will leverage teaching structures at Case Western Reserve University to recruit students.
Overall, FAIR DOs aims to provide about 35/45 hours of training to over 75 students over the proposed five-year
project, with each student research project producing one publication in the Physiome journal--launched by the
International Union of Physiological Sciences. The SPARC Portal will provide findability to these student-
generated open-access models and associated data via its Search and Flatmaps functions, as well as accessible
interactivity via the O2S2PARC simulation platform. Overall, the FAIR DOs effort will provide a unique
educational, mentored experience that will also generate a SPARC ecosystem of interoperating models that
coherently study the neurobiology of digestive and renal epithelial transport. From a didactic “Systems”
perspective, this ecosystem of models will be organized to follow the teaching narrative of the British Medical
Association Award-winning “Medical Physiology 3rd Ed.” textbook, supplemented with recent literature, setting
the stage to further leverage SPARC resources for education in the future.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mechanisms of oxygen off-loading from red blood cells in murine models of human disease
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批准号:10343967
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项目类别:
-
资助金额:$66.46万
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财政年份:2022
-
负责人:Walter F Boron
-
依托单位:
FAIR DOs: Findable, Accessible, Interoperable, Reusable Development of Open Simulation
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批准号:10707353
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项目类别:
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资助金额:$13.06万
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财政年份:2022
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负责人:Walter F Boron
-
依托单位:
Mechanisms of oxygen off-loading from red blood cells in murine models of human disease
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批准号:10548180
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项目类别:
-
资助金额:$65.85万
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财政年份:2022
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负责人:Walter F Boron
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依托单位:
Molecular mechanism of Na+ -coupled HCO3- transporters: transport of CO3= and CO2
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批准号:10187218
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项目类别:
-
资助金额:$69.76万
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财政年份:2021
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负责人:Walter F Boron
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依托单位:
Molecular mechanism of Na+ -coupled HCO3- transporters: transport of CO3= and CO2
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批准号:10398247
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项目类别:
-
资助金额:$66.06万
-
财政年份:2021
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负责人:Walter F Boron
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依托单位:
Cleveland Kidney, Urology and Hematology Training Network
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批准号:10284382
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项目类别:
-
资助金额:$28.9万
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财政年份:2021
-
负责人:Walter F Boron
-
依托单位:
Molecular mechanism of Na+ -coupled HCO3- transporters: transport of CO3= and CO2
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批准号:10640070
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项目类别:
-
资助金额:$67.14万
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财政年份:2021
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负责人:Walter F Boron
-
依托单位:
Cleveland Kidney, Urology and Hematology Training Network
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批准号:10657715
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项目类别:
-
资助金额:$28.9万
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财政年份:2021
-
负责人:Walter F Boron
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依托单位:
Role of RPTP-gamma in sensing and transducing acid-base disturbances in the renal proximal tubule
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批准号:9926240
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项目类别:
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资助金额:$51.28万
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财政年份:2017
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负责人:Walter F Boron
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依托单位:
Multi-scale modeling of gas transport through channels in living cells
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批准号:9198249
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项目类别:
-
资助金额:$57.65万
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财政年份:2015
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负责人:Walter F Boron
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依托单位:
Regulation of Proximal Tubule Transport
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批准号:8272680
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项目类别:
-
资助金额:$49.77万
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财政年份:2009
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负责人:Walter F Boron
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依托单位:
Regulation of Proximal Tubule Transport
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批准号:8473208
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项目类别:
-
资助金额:$48.03万
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财政年份:2009
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负责人:Walter F Boron
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依托单位:
Regulation of Proximal Tubule Transport
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批准号:7827988
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项目类别:
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资助金额:$55.48万
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财政年份:2009
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负责人:Walter F Boron
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依托单位:
Regulation of Proximal Tubule Transport
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批准号:8068332
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项目类别:
-
资助金额:$49.77万
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财政年份:2009
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负责人:Walter F Boron
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依托单位:
Regulation of Proximal Tubule Transport
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批准号:7656131
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项目类别:
-
资助金额:$59.19万
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财政年份:2009
-
负责人:Walter F Boron
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依托单位:
PH REGULATION IN NEURONS AND ASTROCYTES IN HYPOXIA
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批准号:7659693
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项目类别:
-
资助金额:$26.05万
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财政年份:2008
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负责人:Walter F Boron
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依托单位:
Administrative Core Facility
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批准号:7499826
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项目类别:
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资助金额:$9.17万
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财政年份:2007
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负责人:Walter F Boron
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依托单位:
Regulation of Proximal Tubule Bicarbonate Transport
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批准号:7499843
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项目类别:
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资助金额:$19.79万
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财政年份:2007
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负责人:Walter F Boron
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依托单位:
PH REGULATION IN NEURONS AND ASTROCYTES IN HYPOXIA
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批准号:6910143
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项目类别:
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资助金额:$25.09万
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财政年份:2004
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负责人:Walter F Boron
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依托单位:
Cellular and Molecular Studies of Renal Transport
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批准号:6935392
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项目类别:
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资助金额:$179.81万
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财政年份:1996
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负责人:Walter F Boron
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依托单位:
海外基金