Core G: University of Kentucky Alzheimer's Disease Core Center

核心 G：肯塔基大学阿尔茨海默病核心中心

• 批准号: 10662371
• 负责人: LINDA J VAN ELDIK
• 金额: $ 16.33万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10662371
• 关键词: Acceleration; Achievement; Address; Advisory Committees; Alzheimer' s Disease; Alzheimer' s Disease Core Center; Alzheimer' s disease related dementia; Area; Basic Science; Behavioral; Biological Markers; Clinical; Clinical Research; Clinical Trials Design; Communities; Competence; Data Analyses; Dedications; Dementia; Development; Discipline; Early Diagnosis; Education; Educational Activities; Elderly; Environment; Etiology; Exposure to; Faculty; Foundations; Funding; Future; Goals; Image; Individual; Interdisciplinary Study; Kentucky; Knowledge; Leadership; Learning; Liquid substance; Magnetic Resonance Imaging; Mentors; Monitor; Outcome; Participant; Postdoctoral Fellow; Prevention Research; Process; Program Development; Recording of previous events; Research; Research Design; Research Personnel; Research Project Grants; Resources; Scholars Program; Science; Scientist; Standardization; Structure; System; Teacher Professional Development; Training; Training Programs; Translational Research; Universities; career; career development; collaborative environment; education planning; education research; experience; health inequalities; health literacy; high school; improved; innovation; instrument; investigator training; longitudinal analysis; mixed dementia; multidisciplinary; neuropathology; next generation; novel; prevent; professor; programs; recruit; skill acquisition; skills; success; therapy development; training opportunity; treatment research; undergraduate student

Project Summary/Abstract: Research Education Component The Research Education Component (REC) of the UK-ADRC offers a variety of research educational activities and comprehensive, mentored research skills development programs that will enhance the development of the future workforce to meet the nation’s biomedical, behavioral, and clinical needs in Alzheimer’s disease and related dementias (ADRD) research. The REC will leverage resources within and outside the UK-ADRC to create an outstanding, multidisciplinary, and collaborative environment for training the next generation of researchers in scientific areas that parallel the theme of our ADRC (Transitions from Normal to Late-Life, Multi- Etiology Dementias), and with an emphasis on increasing representation of researchers from diverse backgrounds. We will continue to build on a long history of collaborative and dedicated faculty, a strong foundation in multidisciplinary team science, and an outstanding track record of success in mentoring and education of researchers across the training spectrum. We will also establish a new REC Scholar program aimed at junior investigators (Assistant Professors, senior research associates, or clinical fellows). This program will support junior investigators from diverse, multidisciplinary fields to pursue mentored basic, translational, or clinical research in ADRD, and follow a customized training plan to help the scholars move toward their career development goals. This training will be done in a supportive and collaborative academic environment with substantial training resources and an experienced and dedicated training faculty. Scholars will have the opportunity to learn state-of-the-art research skills in disciplines that have been identified as critically needed areas for the ADRC workforce of the future. Examples of training areas where the UK-ADRC has strong expertise include analysis of longitudinal clinical outcomes, clinical trial design, MRI imaging and novel fluid biomarkers, quantitative neuropathology and AD mimics, data analysis/ study design in mixed dementias, and health literacy and inequities. REC goals will involve interactions with all the UK-ADRC Cores and will be achieved through the following specific aims. Aim 1. Provide education programs and research skills development opportunities for investigators at UK. Aim 2. Identify, select, support, and retain REC scholars from diverse backgrounds and disciplines to engage in ADRD research. Aim 3. Develop an individualized mentoring plan and educational program for each REC scholar to enable advancement to independent research and funding in ADRD research. Aim 4. Evaluate progress of the REC scholars, address barriers towards the goal of independence in ADRD research and refine delivery of the program’s educational structure and processes. Following completion of the Program, participants will have the knowledge, expertise, and confidence to successfully pursue a long-term career in dementia research.

项目摘要/摘要：研究教育部分 UK-ADRC 的研究教育部分 (REC) 提供各种研究教育活动 全面的、有指导的研究技能发展计划，将促进该领域的发展 未来的劳动力，以满足国家在阿尔茨海默氏病和 相关痴呆症（ADRD）研究。 REC 将利用 UK-ADRC 内部和外部的资源 为培训下一代创造一个优秀的、多学科的、协作的环境 与我们的 ADRC 主题（从正常到晚年的转变，多 病因学痴呆），并强调增加来自不同领域的研究人员的代表性 背景。我们将继续以长期合作和敬业的教师队伍为基础，建立一支强大的 多学科团队科学基础，以及在指导和指导方面的杰出成功记录 跨培训领域的研究人员教育。我们还将建立一个新的 REC 学者计划 针对初级研究人员（助理教授、高级研究员或临床研究员）。这 该计划将支持来自不同、多学科领域的初级研究人员追求受指导的基础、 ADRD 的转化或临床研究，并遵循定制的培训计划来帮助学者移动 朝着他们的职业发展目标。该培训将在支持和协作的学术机构中进行 拥有丰富的培训资源和经验丰富、敬业的培训师资队伍。学者 将有机会学习已被确定为的学科的最先进的研究技能 ADRC 未来劳动力急需的领域。 UK-ADRC 的培训领域示例 拥有强大的专业知识，包括纵向临床结果分析、临床试验设计、MRI 成像和 新型液体生物标志物、定量神经病理学和 AD 模拟、混合数据分析/研究设计 痴呆症、健康素养和不平等。 REC 目标将涉及与所有 UK-ADRC 核心的互动 并将通过以下具体目标来实现。 目标 1. 为英国的研究人员提供教育计划和研究技能发展机会。 目标 2. 识别、选择、支持和留住来自不同背景和学科的 REC 学者来参与 在 ADRD 研究中。 目标 3. 为每位 REC 学者制定个性化的指导计划和教育计划，以实现 ADRD 研究的独立研究和资助的进展。 目标 4. 评估 REC 学者的进展，解决 ADRD 独立目标的障碍 研究并完善该计划的教育结构和流程。 计划完成后，参与者将拥有知识、专业知识和信心 成功地从事痴呆症研究的长期职业。