Core G: University of Kentucky Alzheimer's Disease Core Center

核心 G：肯塔基大学阿尔茨海默病核心中心

• 批准号: 10662371
• 负责人: LINDA J VAN ELDIK
• 金额: $ 16.33万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10662371
• 关键词: Acceleration; Achievement; Address; Advisory Committees; Alzheimer' s Disease; Alzheimer' s Disease Core Center; Alzheimer' s disease related dementia; Area; Basic Science; Behavioral; Biological Markers; Clinical; Clinical Research; Clinical Trials Design; Communities; Competence; Data Analyses; Dedications; Dementia; Development; Discipline; Early Diagnosis; Education; Educational Activities; Elderly; Environment; Etiology; Exposure to; Faculty; Foundations; Funding; Future; Goals; Image; Individual; Interdisciplinary Study; Kentucky; Knowledge; Leadership; Learning; Liquid substance; Magnetic Resonance Imaging; Mentors; Monitor; Outcome; Participant; Postdoctoral Fellow; Prevention Research; Process; Program Development; Recording of previous events; Research; Research Design; Research Personnel; Research Project Grants; Resources; Scholars Program; Science; Scientist; Standardization; Structure; System; Teacher Professional Development; Training; Training Programs; Translational Research; Universities; career; career development; collaborative environment; education planning; education research; experience; health inequalities; health literacy; high school; improved; innovation; instrument; investigator training; longitudinal analysis; mixed dementia; multidisciplinary; neuropathology; next generation; novel; prevent; professor; programs; recruit; skill acquisition; skills; success; therapy development; training opportunity; treatment research; undergraduate student

Project Summary/Abstract: Research Education Component The Research Education Component (REC) of the UK-ADRC offers a variety of research educational activities and comprehensive, mentored research skills development programs that will enhance the development of the future workforce to meet the nation’s biomedical, behavioral, and clinical needs in Alzheimer’s disease and related dementias (ADRD) research. The REC will leverage resources within and outside the UK-ADRC to create an outstanding, multidisciplinary, and collaborative environment for training the next generation of researchers in scientific areas that parallel the theme of our ADRC (Transitions from Normal to Late-Life, Multi- Etiology Dementias), and with an emphasis on increasing representation of researchers from diverse backgrounds. We will continue to build on a long history of collaborative and dedicated faculty, a strong foundation in multidisciplinary team science, and an outstanding track record of success in mentoring and education of researchers across the training spectrum. We will also establish a new REC Scholar program aimed at junior investigators (Assistant Professors, senior research associates, or clinical fellows). This program will support junior investigators from diverse, multidisciplinary fields to pursue mentored basic, translational, or clinical research in ADRD, and follow a customized training plan to help the scholars move toward their career development goals. This training will be done in a supportive and collaborative academic environment with substantial training resources and an experienced and dedicated training faculty. Scholars will have the opportunity to learn state-of-the-art research skills in disciplines that have been identified as critically needed areas for the ADRC workforce of the future. Examples of training areas where the UK-ADRC has strong expertise include analysis of longitudinal clinical outcomes, clinical trial design, MRI imaging and novel fluid biomarkers, quantitative neuropathology and AD mimics, data analysis/ study design in mixed dementias, and health literacy and inequities. REC goals will involve interactions with all the UK-ADRC Cores and will be achieved through the following specific aims. Aim 1. Provide education programs and research skills development opportunities for investigators at UK. Aim 2. Identify, select, support, and retain REC scholars from diverse backgrounds and disciplines to engage in ADRD research. Aim 3. Develop an individualized mentoring plan and educational program for each REC scholar to enable advancement to independent research and funding in ADRD research. Aim 4. Evaluate progress of the REC scholars, address barriers towards the goal of independence in ADRD research and refine delivery of the program’s educational structure and processes. Following completion of the Program, participants will have the knowledge, expertise, and confidence to successfully pursue a long-term career in dementia research.

项目概要/摘要：研究教育部分 英国ADRC的研究教育部分（REC）提供各种研究教育活动 和全面的，指导性的研究技能发展计划，将加强发展的 未来的劳动力，以满足国家的生物医学，行为，和临床需要在阿尔茨海默病和 相关痴呆症（ADRD）研究。REC将利用UK-ADRC内外的资源， 为培养下一代创造一个杰出的，多学科的和协作的环境 在科学领域的研究人员，平行我们的ADRC的主题（从正常到晚年的过渡，多， 病因学痴呆症），并强调增加来自不同领域的研究人员的代表性 背景我们将继续建立在合作和敬业的教师，一个强大的历史 多学科团队科学的基础，以及在指导和 研究人员在整个培训范围内的教育。我们还将建立一个新的REC奖学金计划 针对初级研究者（助理教授、高级研究员或临床研究员）。这 该计划将支持来自不同，多学科领域的初级研究人员， 翻译，或临床研究在ADRD，并遵循定制的培训计划，以帮助学者移动 实现职业发展目标。这项培训将在一个支持和合作的学术 环境与大量的培训资源和经验丰富，专门的培训教师。学者 将有机会学习国家的最先进的研究技能的学科已被确定为 未来ADRC劳动力急需的领域。英国-ADRC培训领域的例子 具有很强的专业知识，包括纵向临床结局分析、临床试验设计、MRI成像和 新型液体生物标志物、定量神经病理学和AD模拟物，混合研究中的数据分析/研究设计 失智症、健康知识普及和不平等。REC目标将涉及与所有UK-ADRC核心的互动 并将通过以下具体目标来实现。 目标1.为英国的研究人员提供教育项目和研究技能发展机会。 目标2.识别，选择，支持和留住来自不同背景和学科的REC学者， 在ADRD研究中。 目标3。为每个REC学者制定个性化的指导计划和教育计划， 促进ADRD研究的独立研究和资助。 目标4。评估REC学者的进展，解决ADRD实现独立目标的障碍 研究和完善该计划的教育结构和过程的交付。 完成该计划后，参与者将拥有知识，专业知识和信心， 在痴呆症研究方面成功地追求长期的职业生涯。