Laboratory for Early Psychosis Research (LEAP)

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This is a Supplement application for the LEAP Center (P50MH115846) in response to the Notice of Special Interest (OD‐22‐032) for research on Sexual and Gender Minority (SGM) populations. Research indicates that SGM individuals are at higher risk of adverse outcomes due to psychiatric disorders compared to those in the general population. But this has not yet been examined in the setting of a first episode psychosis (FEP). The LEAP Center analyzes various FEP datasets and examines patterns of clinical trajectory and outcomes. Therefore, we are ideally positioned to examine the impact of SGM status in FEP populations. In this project, we will start by examining existing FEP datasets to understand the characteristics of the SGM population within FEP, then we will conduct interviews and focus groups to validate and extend the findings from existing data. Our preliminary data indicate SGM individuals constitute a substantial proportion of the FEP population sand we expect that we may see adverse outcomes within the SGM population.