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Laboratory for Early Psychosis Research (LEAP)

早期精神病研究实验室 (LEAP)

基本信息

批准号：
10559013
负责人：
MIGUEL HERNAN
金额：
$ 10万
依托单位：
MCLEAN HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-05-15 至 2023-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10559013
关键词：
Address Adolescence Adverse event Age Age of Onset Bisexual Caring Characteristics Clinic Clinical Collection Coordinated Specialty Care Data Data Collection Data Element Data Set Diagnosis Early treatment Emergency department visit Evaluation Event Feeling suicidal Focus Groups Gender Identity General Population Geography Heterogeneity Individual Infrastructure Intervention Interview Joints Knowledge Laboratories Literature Longitudinal Studies Massachusetts Measurement Measures Mental Health Mental disorders National Institute of Mental Health Nature Outcome Overdose Participant Patients Pattern Pharmaceutical Preparations Policies Population Positioning Attribute Psychoses Psychotic Disorders Research Risk Sampling Sex Orientation Sexual and Gender Minorities Silicon Dioxide Suicide Suicide attempt Time Uncertainty Vulnerable Populations Work adverse event risk adverse outcome age group care episode cohort comorbidity data harmonization early psychosis evidence base experience first episode psychosis gender minority group high risk hospitalization rates improved interest knowledge base minority patient non-suicidal self injury patient population peer population based preference programs response service engagement substance use suicidal risk university student young adult

项目摘要

This is a Supplement application for the LEAP Center (P50MH115846) in response to the Notice of Special Interest (OD‐22‐032) for research on Sexual and Gender Minority (SGM) populations. Research indicates that SGM individuals are at higher risk of adverse outcomes due to psychiatric disorders compared to those in the general population. But this has not yet been examined in the setting of a first episode psychosis (FEP). The LEAP Center analyzes various FEP datasets and examines patterns of clinical trajectory and outcomes. Therefore, we are ideally positioned to examine the impact of SGM status in FEP populations. In this project, we will start by examining existing FEP datasets to understand the characteristics of the SGM population within FEP, then we will conduct interviews and focus groups to validate and extend the findings from existing data. Our preliminary data indicate SGM individuals constitute a substantial proportion of the FEP population sand we expect that we may see adverse outcomes within the SGM population.

这是LEAP中心(P50MH115846)的补充申请，以回应对性少数群体和性别少数群体的研究特别感兴趣(OD-22-032)。研究表明SGM患者因精神障碍而产生不良后果的风险更高与普通人群相比。但这还没有在第一次的背景下进行审查发作性精神病(FEP)。LEAP中心分析各种FEP数据集并检查临床轨迹和结果。因此，我们处于研究SGM影响的理想位置在FEP人群中的地位。在本项目中，我们将从检查现有FEP数据集开始，以了解了解FEP内SGM人群的特征，然后我们将进行访谈和焦点小组以验证和扩展现有数据的发现。我们的初步数据显示SGM个人占FEP人口的相当大比例，我们预计我们可能会看到不利的在SGM人群中取得的成果。