Development of an online, theory-based intervention to reduce e-cigarette use and susceptibility to smoking in young adults: A pilot study

开发基于理论的在线干预措施，以减少年轻人的电子烟使用和吸烟易感性：一项试点研究

• 批准号: 10664232
• 负责人: Denise Dao Tran
• 金额: $ 18.45万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-15 至 2028-02-29
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10664232
• 关键词: Address; Adolescent; Affect; Age; Alcohol consumption; Area; Behavior; Belief; Cardiovascular Diseases; Cardiovascular system; Cellular Phone; Chemicals; Cigarette; Clinical; Cognition; Cognitive; Curiosities; Data; Development; Early Intervention; Education; Educational Curriculum; Electronic cigarette; Ethnic Origin; Evaluation; Feedback; Female; Frequencies; Future; Grant; Growth; Health; Individual; Internet; Intervention; Interview; Link; Long-Term Effects; Longitudinal Studies; Longitudinal cohort; Lung diseases; Malignant Neoplasms; Manuscripts; Mentors; Mentorship; Methodology; Motivation; Nicotine; Nicotine Dependence; Outcome; Perception; Personal Satisfaction; Pilot Projects; Play; Policies; Population; Populations at Risk; Predisposition; Prevalence; Procedures; Proliferating; Public Health; Publishing; Race; Randomized; Randomized, Controlled Trials; Reporting; Research; Research Design; Research Personnel; Resistance; Risk Reduction; Self Efficacy; Services; Smoke; Smoking; Smoking Behavior; Surveys; Target Populations; Techniques; Technology; Testing; Text Messaging; Time; Tobacco; Tobacco use; Training; Treatment Efficacy; Work; Writing; Youth; acceptability and feasibility; addiction; advanced analytics; age group; behavior change; brief intervention; cigarette smoke; cigarette smoking; cohort; combustible cigarette; combustible tobacco; comparison control; design; digital; effectiveness evaluation; efficacy evaluation; efficacy testing; electronic cigarette use; electronic cigarette user; evidence base; follow-up; interest; intervention effect; male; meetings; mobile phone based intervention; motivational enhancement therapy; multidisciplinary; never smoking; normative feedback; online intervention; peer; personalized normative feedback; pilot test; prevent; preventive intervention; programs; recruit; respiratory; risk mitigation; screening; sex; skills; smoking addiction; smoking initiation; smoking prevalence; social; social norm; substance use; theories; therapy design; therapy development; vaper; vaping; web-based intervention; young adult

PROJECT SUMMARY/ABSTRACT There has been widespread proliferation of e-cigarette use (i.e., vaping) among young adults (YAs), as well as evidence of strong associations between vaping with cigarette initiation and continued smoking. Despite this, there are no evidence-based vaping interventions with tailored content specifically for YAs that is easily accessible to this age group (i.e., online and viewable on mobile phones) and targets smoking susceptibility. Perceived social norms, such as overestimations of how prevalent and accepted vaping and smoking are, and misperceptions of the harms of vaping and smoking appear to play key roles in YA vaping and smoking behaviors. Indeed, beliefs about social norms, perceptions of harm, and motivations associated with vaping and smoking are linked to vaping frequency and likelihood of smoking onset among YAs; thus, targeting these in a brief intervention can be efficacious. Vaping and smoking prevalence and acceptance will be collected from a longitudinal cohort of YAs ages 18-22 (N~2200; Aim 1). These data from Aim 1 will be used to develop and beta test a brief, online intervention that incorporates personalized normative feedback (PNF), aspects informed by Motivational Interviewing, and education to address misperceptions about vaping and smoking norms and harm. As part of this aim, we will evaluate acceptability and feasibility of intervention content, including believability of the norms presented and interest in the content (Aim 2). The finalized intervention will then be pilot tested among YA current e-cigarette users who have never smoked (N = 50) with an assessment-only control (N = 50; Aim 3) to determine efficacy of the program in reducing vaping frequency and smoking susceptibility. Results from this project will be informative in (1) elucidating social and cognitive factors that contribute to and maintain vaping behaviors in YAs and (2) inform future intervention approaches designed to mitigate the risks of nicotine dependence among the rapidly increasing population of young vapers. Results will be used as framework for an R01 application to conduct a larger randomized controlled trial to test the efficacy of this intervention. I enter this project with strong quantitative skills as a clinical researcher with growing proficiency in tobacco research. This K01 is essential for me to develop additional expertise in areas that will support my objectives of becoming an independent, multidisciplinary investigator of determinants of substance use in YAs. This proposal will afford me with protected research time to develop expertise in a) predictors of addiction and its application to tobacco-product use in youth, b) technology-based substance use intervention development and evaluation, and c) longitudinal study design and advanced analytic methodologies, with mentorship to further refine my skills in the application of my research to inform policy, prevention, and early intervention efforts. I have worked closely with my proposed mentors to develop an ambitious but feasible training curriculum that integrates expert mentoring; coursework, seminars, and readings; scientific meetings; and growth in advanced analyses and manuscript and grant writing skills.

项目摘要/摘要 电子烟的使用已经广泛扩散（即，年轻人（YAs），以及 有证据表明，电子烟与吸烟开始和继续吸烟之间存在强烈的关联。尽管如此， 没有基于证据的vaping干预措施，专门为YAs定制内容， 这个年龄段的人（即，在线并可在移动的电话上查看），并针对吸烟 易感性感知的社会规范，例如高估了电子烟的流行和接受程度， 吸烟是，对vaping和吸烟危害的误解似乎在YA vaping中起着关键作用 吸烟行为。事实上，对社会规范的信念，对伤害的看法，以及相关的动机， 与vaping和吸烟有关的是vaping频率和YA中吸烟发作的可能性;因此， 针对这些问题进行简短的干预可能是有效的。电子烟和吸烟的流行和接受将 从18-22岁的YA的纵向队列中收集（N~2200;目标1）。目标1的这些数据将是 用于开发和测试一个简短的在线干预，其中包含个性化的规范反馈 (PNF)，通过动机面试了解的方面，以及解决对vaping的误解的教育 吸烟的规范和危害。作为这一目标的一部分，我们将评估干预的可接受性和可行性 内容，包括所提出的规范的可信度和对内容的兴趣（目标2）。最终确定的 然后将在从未吸烟的YA当前电子烟使用者（N = 50）中进行试点测试， 仅评估对照（N = 50;目标3），以确定该计划在减少吸烟频率方面的有效性 和吸烟易感性。从这个项目的结果将是翔实的（1）阐明社会和认知 有助于和维持YAs中的vaping行为的因素，以及（2）为未来的干预方法提供信息 旨在降低快速增长的年轻人口中尼古丁依赖的风险 电子烟结果将用作R 01申请的框架，以进行更大规模的随机对照 来测试这种干预的有效性。我进入这个项目与强大的定量技能作为一个临床 在烟草研究方面越来越熟练的研究员。这个K 01是必不可少的，我开发额外的 专业知识领域，将支持我的目标，成为一个独立的，多学科的调查员， 在YAs中使用物质的决定因素。这个建议将使我有受保护的研究时间来发展 专门知识：a）成瘾预测及其在青年烟草制品使用中的应用，B）基于技术的 物质使用干预开发和评估，以及c）纵向研究设计和高级 分析方法，与导师，以进一步完善我的技能，在我的研究应用，以告知 政策、预防和早期干预工作。我与我的导师密切合作， 一个雄心勃勃但可行的培训课程，整合了专家指导;课程，研讨会， 阅读;科学会议;和先进的分析和手稿和赠款写作技能的增长。