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Improving Remote Breathalyzer Procedures used by Clinicians and Researchers to Remotely Monitor Alcohol Use

改进临床医生和研究人员用于远程监测酒精使用情况的远程呼吸分析仪程序

基本信息

批准号：
10670837
负责人：
Donald M Dougherty
金额：
$ 18.96万
依托单位：
UNIVERSITY OF NORTH TEXAS
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-01 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10670837
关键词：
Abstinence Adopted Adoption Alcohol consumption Alcohols Area Behavior Therapy Biological Markers Blood Blood alcohol level measurement Blood specimen Breath Tests Clinical Data Detection Devices Disadvantaged Effectiveness Event Excretory function Face Failure Forensic Medicine Frequencies Future Health Technology Heavy Drinking Hour Incentives Individual Intervention Manufacturer Measurement Measures Methods Monitor Motivation National Institute on Alcohol Abuse and Alcoholism Participant Pattern Periodicals Persons Physical activity Procedures Protocols documentation Public Health Recommendation Reporting Research Research Personnel Sampling Secure Skin Sleep Specificity Spottings Strategic Planning Testing Text Messaging Time Violence Waiting Lists Work alcohol measurement alcohol monitoring breath alcohol measurement clinical practice contingency management cost drinking driving under influence dual diagnosis eHealth handheld mobile device improved liver transplantation offender phosphatidylethanol recruit remote monitoring secondary analysis social stigma wearable sensor technology

项目摘要

Project Summary/Abstract The availability of wearable biosensors that continuously and/or remotely monitor alcohol use is increasing and has created new opportunities for research and intervention in clinical practice and forensic settings. Our previous work in this area has focused on transdermal alcohol monitors, which remotely and continuously monitor alcohol excreted through the skin. While such devices, like Secure Continuous Remote Alcohol Monitors, have been validated and found reliable, they have some disadvantages that limit widespread adoption including availability, cost, size, interference with physical activities, and stigma. One alternative is the use of breathalyzers that remotely sample and report breath alcohol levels across the day. These are becoming the preferred method for monitoring alcohol use in settings where continuous monitoring for alcohol consumption is required. Although remote breathalyzers are accurate for detecting current blood alcohol levels and identifying the individual providing the sample through facial recognition, their primary limitation could be the failure to detect drinking when monitoring is absent during the "off- cycle”; the 10 hours between early 9pm and 6am when heavy alcohol use could occur. Individuals who have difficulty remaining abstinent and may adopt a pattern of drinking during “off-cycle” periods to avoid the negative consequences associated with positive breath samples. We propose that current practices for remote alcohol breath monitoring in research, clinical, and judicial settings are inadequate to detect drinking. Specifically, we aim to evaluate the accuracy of remote breath alcohol monitoring to detect drinking events; and determine if drinking undetected by remote breath alcohol monitoring can be identified by phosphatidylethanol measurement. We expect that breath alcohol monitoring (and infrequent blood spot sampling) will be more acceptable than transdermal alcohol monitoring. This work challenges current practices by providing evidence of “off-cycle” drinking (Aim 1) and will improve existing methods by validating remote breath testing plus periodic measures of phosphatidylethanol (Aim 2). We also will determine the optimal frequency of phosphatidylethanol measurements to confidently confirm abstinence or identify those who may be motivated to adopt patterns of drinking to avoid detection and consequences (Aim 2). This work will help redefine remote alcohol-use monitoring procedures and significantly improve clinical, forensic and research practices.

项目总结/文摘