Biostatistics and Bioinformatics Shared Resources

生物统计学和生物信息学共享资源

• 批准号: 10670839
• 负责人: Xi Steven Chen
• 金额: $ 22.18万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-10 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10670839
• 关键词: Applications Grants; Basic Science; Bioinformatics; Bioinformatics Shared Resource; Biometry; Biostatistics Shared Resource; Biotechnology; Calendar; Cancer Center Support Grant; Clinical; Clinical Sciences; Clinical Trials; Clinical Trials Design; Collaborations; Comprehensive Cancer Center; Consultations; Data; Data Analyses; Education; Educational process of instructing; Ensure; Extramural Activities; Faculty; Funding; Funding Opportunities; Grant; Laboratories; Malignant Neoplasms; Manuscripts; Mentors; Methodology; Methods; Monitor; National Cancer Institute; Peer Review; Phase; Population Research; Population Sciences; Preparation; Protocols documentation; Publications; Reporting; Research; Research Design; Research Personnel; Resource Sharing; Resources; Safety; Sample Size; Science; Services; Statistical Computing; Training and Education; anticancer research; data acquisition; experience; member; novel; population based; power analysis; programs; research study; success; tool

PROJECT SUMMARY: BIOSTATISTICS AND BIOINFORMATICS SHARED RESOURCE The Biostatistics and Bioinformatics Shared Resource (BBSR) provides Sylvester Comprehensive Cancer Center (Sylvester) investigators access to contemporary biostatistics, bioinformatics, and computational expertise in support of clinical trials as well as laboratory- and population-based cancer research studies. This critical, highly utilized shared resource contributes to all phases of research, including study design, data analysis and interpretation, and education in quantitative science methods and application tools. Over the past three years, the BBSR has greatly expanded its accessibility, capacity, and breadth and now comprises a Director (with expertise in both biostatistics and bioinformatics), four biostatisticians, and three bioinformaticians. Advances in biotechnologies and computing have significantly increased the need for the sophisticated statistical methodologies provided by the resource and BBSR faculty and staff have extensive cancer-specific experience and expertise. BBSR staff are readily available to Sylvester investigators, participate regularly in all three research programs, and engage other shared resource leaders to ensure comprehensive and seamless support for Sylvester members. The BBSR provided services to 60 Sylvester members in calendar year 2017 (77% of which had peer-reviewed funding), which comprised 65% of BBSR usage. The BBSR serves a critical need for Sylvester, ensuring statistical validity of research across the continuum from grant applications to basic, clinical, translational and population-based research to peer- reviewed publications.

项目摘要：生物统计学和生物信息学共享资源 生物统计学和生物信息学共享资源（BBSR）为Sylvester综合癌症提供 中心（西尔维斯特）调查人员获得当代生物统计学，生物信息学和计算 支持临床试验以及基于实验室和人群的癌症研究方面的专业知识。这 关键，高度利用的共享资源有助于研究的所有阶段，包括研究设计，数据 分析和解释，以及定量科学方法和应用工具中的教育。过去 三年来，BBSR大大扩展了其可及性，能力和广度，现在包括一个 主任（在生物统计学和生物信息学方面都有专业知识），四位生物统计学家和三名 生物信息学家。生物技术和计算的进步显着增加了对 资源提供的复杂统计方法和BBSR教职员工拥有广泛的 特定于癌症的经验和专业知识。 Sylvester调查人员很容易就可以使用BBSR员工 定期参加所有三个研究计划，并参与其他共享资源领导者以确保 对西尔维斯特成员的全面和无缝的支持。 BBSR为60 Sylvester提供服务 2017日历年的成员（其中77％的同行评审资金）占BBSR的65％ 用法。 BBSR对Sylvester构成了迫切需求，确保了研究的统计有效性 从赠款申请到基本，临床，转化和基于人群的基础研究的连续性 审查出版物。