Administrative Core

行政核心

• 批准号: 10696181
• 负责人: Jana Portnow
• 金额: $ 25.19万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-13 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10696181
• 关键词: Alabama; Basic Science; Biological Products; Biometry; Brain Neoplasms; Cities; Clinical Research; Clinical Trials; Collaborations; Data; Development; Ensure; Funding; Glioblastoma; Goals; Infrastructure; Institution; Leadership; Legal patent; Microdialysis; Modeling; Occupational activity of managing finances; Patient-Focused Outcomes; Patients; Performance; Pilot Projects; Policies; Preparation; Progress Reports; Publications; Reporting; Research; Research Activity; Research Institute; Research Personnel; Research Project Grants; Resource Sharing; Resources; Statistical Data Interpretation; Structure; Technology Transfer; Testing; Therapeutic; Translational Research; Translations; Travel; United States National Institutes of Health; Universities; Visualization; Work; clinical development; data integration; data management; data quality; design; effective therapy; electronic data; first-in-human; human subject protection; improved outcome; meetings; member; novel; novel therapeutics; programs; quality assurance; small molecule inhibitor; translational genomics; trial design

PROJECT SUMMARY – ADMINISTRATIVE CORE The overall goal of the Administrative Core (Admin Core) is to provide the organizational infrastructure necessary to stimulate research and to expedite the translation of discoveries into new and better treatments for glioblastoma (GBM). The Admin Core will facilitate these activities by providing leadership, financial management, and an administrative structure designed to efficiently coordinate the activities of the research projects, shared resources cores, the Glioblastoma Therapeutics Network (GTN), and the Network Coordination Center (NCC). In addition, the Admin Core incorporates a biostatistical component and will oversee all statistical support to all Projects and Cores. Specifically, the Admin Core will: 1) Provide leadership, organizational support, oversight of data management, and financial management for the U19 investigators; 2) Promote integration of the three projects to enhance interaction among the three participating institutions (City of Hope, University of Alabama at Birmingham and the Translational Genomics Research Institute), the internal advisory board (IAB) and other GTN U19 Research Centers; 3) Facilitate collaboration with other U19 Research Centers to fund and oversee pilot projects; 4) Serve as the liaison working with the NCC to implement network best practices and policies; and 5) Provide biostatistical expertise to support basic science, translational, and clinical research. The proposed U19 structure, consisting of three participating institutions, will be directed by Drs. Portnow (Contact PI) and Badie (MPI) at City of Hope. The members of this team are well acquainted and have a track record of collaborating on GBM research projects and leading the City of Hope Brain Tumor Program. Through performance of the Specific Aims, the Admin Core will ensure effective functioning of the U19 to maximize our efficiency, conserve resources, and expedite clinical development of novel therapies for GBM.

项目总结-行政核心