Curriculum in Experimental Design and Statistics for Biomedical Researchers

生物医学研究人员实验设计和统计学课程

• 批准号: 10696256
• 负责人: Gary A Churchill
• 金额: $ 8.98万
• 依托单位: JACKSON LABORATORY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10696256
• 关键词: Acceleration; Acute; Biomedical Research; Collaborations; Communities; Computer software; Connecticut; Creativeness; Data; Data Analyses; Educational Curriculum; Educational process of instructing; Educational workshop; Experimental Designs; Explosion; FAIR principles; Failure; Foundations; Goals; Internet; Investigation; Knowledge; Licensing; Maine; Mentors; Methods; Outcome; Positioning Attribute; Postdoctoral Fellow; Process; Production; Public Health; Publishing; R programming language; Randomized; Recording of previous events; Reproducibility; Research; Research Personnel; Role; Science; Self Correction; Series; Statistical Data Interpretation; Statistical Methods; Structure; Systems Biology; Testing; The Jackson Laboratory; Time; Training; blind; career; curriculum development; data management; design; empowerment; experimental study; fortification; high throughput analysis; human disease; inferential statistics; insight; multidimensional data; neglect; practical application; pre-doctoral; sound; statistics; web site

PROJECT SUMMARY For many decades biomedical research has benefitted from experimental design and statistical methods that give studies the power to reveal underlying mechanisms and processes. In spite of their long history and empowering role in research, experimental design and statistical principles are not well understood by experimental biologists. Our goal is to increase the number of biomedical researchers who are fluent in experimental design and statistics by developing a curriculum that provides both the conceptual background and applied practice for sound and reproducible experiments. To refine this curriculum, we will test and evaluate the curriculum with an audience of postdoctoral and predoctoral researchers at the Jackson Laboratory campuses in Maine and Connecticut. To disseminate the curriculum broadly, we will publish it as a website under an open access license for self-study and for teaching. By building, testing, and disseminating an openly accessible curriculum in experimental design and statistics, we expect to build statistical fluency among biomedical researchers. By building this fluency, we expect these researchers to find new insights into the complexity of human disease. As a result biomedical studies will have more power to uncover mechanisms and processes, which will accelerate progress in human disease research.

项目总结