Curriculum in Experimental Design and Statistics for Biomedical Researchers

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PROJECT SUMMARY For many decades biomedical research has benefitted from experimental design and statistical methods that give studies the power to reveal underlying mechanisms and processes. In spite of their long history and empowering role in research, experimental design and statistical principles are not well understood by experimental biologists. Our goal is to increase the number of biomedical researchers who are fluent in experimental design and statistics by developing a curriculum that provides both the conceptual background and applied practice for sound and reproducible experiments. To refine this curriculum, we will test and evaluate the curriculum with an audience of postdoctoral and predoctoral researchers at the Jackson Laboratory campuses in Maine and Connecticut. To disseminate the curriculum broadly, we will publish it as a website under an open access license for self-study and for teaching. By building, testing, and disseminating an openly accessible curriculum in experimental design and statistics, we expect to build statistical fluency among biomedical researchers. By building this fluency, we expect these researchers to find new insights into the complexity of human disease. As a result biomedical studies will have more power to uncover mechanisms and processes, which will accelerate progress in human disease research.