Adult Changes in Thought (ACT) Research Program Core A: Administrative Core

成人思想转变 (ACT) 研究计划核心 A：行政核心

• 批准号: 10672342
• 负责人: KatieRose Johnson
• 金额: $ 130万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-15 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10672342
• 关键词: Accountability; Adult; Aging; Agreement; Alzheimer' s disease related dementia; Ancillary Study; Collaborations; Communication; Communication Methods; Communities; Complex; Conflict (Psychology); Custom; Data; Data Aggregation; Data Set; Dementia; Deposition; Documentation; Elderly; Electronics; Enrollment; Ensure; Evaluation; Funding; Goals; Institution; International; Interview; Lead; Leadership; Life Cycle Stages; Logistics; Measurable; Modernization; National Institute on Aging; Newsletter; Online Systems; Outcome; Participant; Performance; Phenotype; Policies; Privatization; Procedures; Process; Productivity; Program Evaluation; Reporting; Research; Research Activity; Research Personnel; Research Project Grants; Resource Sharing; Resources; Risk Factors; Role; Science; Site; Standardization; Structure; Surveys; Trust; Vertebral column; Vision; Work; cohort; data dissemination; data sharing; data standards; experience; follow-up; hands-on learning; human subject; improved; meetings; neuroimaging; neuropathology; operation; programs; query tools; repository; social media; success; symposium; timeline; web site; webinar

The overall goals of the Adult Changes in Thought (ACT) U19 Research Program are to (1) expand ACT cohort enrollment with improved follow-up, phenotyping of life course risk factors, and new neuroimaging and neuropathology outcomes; (2) support Projects studying the spectrum of healthy functioning to Alzheimer’s and related dementias in older adults; and (3) expand and improve ACT’s dissemination of data and resources to the research community. To accomplish these goals, the ACT U19 Program includes three scientific research Projects, six resource Cores, an External Advisory Board, several committees, and many institutional partners. Core A: Administrative Core is a required component and will provide overall leadership and oversight to the entire ACT U19 Program. The Administrative Core will support all Projects and Cores in effective research organization and communication by providing team-based leadership, clear timelines, measurable milestones, and administrative policies. We will create private and public websites and plan interactive Program-wide activities to maintain open communication, collaboration, dissemination, and resource sharing. The Administrative Core will facilitate collaborations with new investigators and support mechanisms to meaningfully share ACT U19 Program data. These mechanisms include a state-of-the-art public website with downloadable datasets with clear documentation; a large, rigorous ACT repository maintained in collaboration with the Data and Analysis Core to support standardized data sharing; an online Data Query Tool to support preliminary aggregate data requests; and reliable administrative processes and procedures for new data requests. Importantly, we will work with the Data and Analysis Core to oversee the logistics, flow, and tracking of all participant data in the ACT Repository, between Projects and Cores, and with any ACT-related ancillary studies. The Administrative Core will provide centralized support of the ACT U19 Program’s logistic and financial requirements. This includes overseeing day-to-day activities; communicating with the National Institute on Aging, External Advisory Board, and supporting committees; and setting the Program’s policies, governance, communication methods, and administrative procedures. Finally, we will undertake a biannual evaluation to improve ACT U19 Program performance. The evaluation will focus on the extent of integration, quality of communication, and scientific productivity across the entire U19 Program to promote best practices in communication, administration, and implementation of research activities. The Administrative Core is the operational backbone of our ACT U19 Program and includes a strong senior leadership team with several small, nimble committees to effectively manage work across all Projects and Cores. We will modernize and improve many of our current administrative procedures and policies to ensure a smooth transition from the U01 to the larger U19 Program. Given our prior experience in leadership, collaboration, and research project coordination, we are confident that this Administrative Core can lead the ACT U19 Program to success.

成人思想变化（ACT）U19研究计划的总体目标是（1）扩大ACT 队列入组，改善随访、生命过程风险因素表型分析和新的神经影像学检查， 神经病理学结果;（2）支持研究阿尔茨海默氏症健康功能谱的项目， （3）扩大和改善ACT的数据和资源传播， 研究界。为了实现这些目标，ACT U19计划包括三项科学研究 项目，六个资源核心，一个外部咨询委员会，几个委员会和许多机构合作伙伴。 核心A：行政核心是一个必要的组成部分，将为 整个ACT U19计划。行政核心将支持所有项目和核心进行有效的研究 通过提供基于团队的领导，明确的时间表，可衡量的里程碑， 和行政政策。我们将建立私人和公共网站，并计划互动程序 保持开放的沟通、协作、传播和资源共享的活动。的 行政核心将促进与新调查员的合作，并支持各种机制， 有意义地分享ACT U19计划数据。这些机制包括一个最先进的公共网站， 可下载的数据集和清晰的文档;协作维护的大型、严格的ACT存储库 与数据和分析核心支持标准化的数据共享;在线数据查询工具，以支持 初步汇总数据请求;新数据的可靠行政程序 请求。重要的是，我们将与数据和分析核心合作，监督物流、流程和跟踪 ACT存储库中的所有参与者数据，在项目和核心之间，以及与任何ACT相关的辅助 问题研究行政核心将为ACT U19计划的后勤和管理提供集中支持。 财务要求。这包括监督日常活动;与国家 老龄问题研究所、外部咨询委员会和支持委员会;制定方案的政策， 管理、沟通方法和行政程序。最后，我们将进行一年两次的 提高ACT U19计划的绩效。评价将侧重于一体化的程度， 沟通质量和整个U19计划的科学生产力，以促进最佳实践 在沟通，管理和研究活动的实施。行政核心是 我们的ACT U19计划的运营骨干，包括一个强大的高级领导团队， 小型、灵活的委员会，以有效管理所有项目和核心的工作。我们将实现现代化， 改进我们目前的许多行政程序和政策，以确保从U 01顺利过渡 到更大的U19计划。鉴于我们在领导、合作和研究项目方面的经验， 协调，我们相信，这一行政核心可以带领ACT U19计划取得成功。