Rurality and Heart Failure: The Southern Community Cohort Study

农村和心力衰竭：南方社区队列研究

• 批准号: 10699752
• 负责人: Veronique Roger
• 金额: $ 24.53万
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10699752
• 关键词: Age; American Heart Association; Area; Black race; Blood Circulation; Cardiovascular Diseases; Censuses; Code; Cohort Studies; Communities; Commuting; Data; Enrollment; Epidemiology; Goals; Health behavior; Heart failure; Incidence; Individual; Low income; Medicaid; Medicare; Modeling; Oral; Outcome; Participant; Persons; Primary Prevention; Prospective, cohort study; Publishing; Race; Risk; Rural; Rural Health; Rural Population; Services; Socioeconomic Status; Southeastern United States; Standardization; Testing; United States Centers for Medicare and Medicaid Services; Urban Population; Woman; black men; black women; cardiovascular risk factor; cohort; demographics; design; experience; follow-up; hazard; health inequalities; meetings; men; mortality; population based; rural area; rurality; sex; study population

Summary of findings Within the Southern Community cohort study population receiving services from Medicare or Medicaid, twenty percent of participants resided in rural areas. Over 13-years median follow-up, the age-adjusted HF incidence was 29.6/1,000 person years for urban and 36.5/1,000 person years for rural participants; p<0.001. After adjustment for demographics, CV risk factors, health behaviors, and SES, rural participants had a 19% greater risk of incident HF (HR 1.19, 95% CI 1.13-1.26) compared to their urban counterparts. The rurality associated risk of heart failure varied across race-sex groups and was greatest among Black men (Hazard ratio 1.34, 95% CI 1.19-1.51), followed by White women (Hazard ratio 1.21, 95% CI 1.06-1.38) and Black women (Hazard ratio 1.18, 95% CI 1.08-1.28). Among White men, rurality was not associated with greater risk of incident HF (Hazard ratio 0.97, 95% CI 0.81-1.15). We identified that among predominantly low-income individuals in the southeastern US, rurality was associated with an increased risk of HF among women and Black men, which persisted after adjustment for cardiovascular risk factors and socio-economic status. This inequity points to a need for additional emphasis on primary prevention of HF among rural populations. This data was presented as an oral abstract at the American Heart Association Epidemiology Meeting in March 2022 and published as an abstract: Turecamo S, Xu M, Joo J, Dixon D, Gupta DK, Lipworth L, Roger VL. Rurality and Incident Heart Failure Risk in The Southern Community Cohort Study. Circulation. 2022;145(Suppl_1).

调查结果摘要