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The 6th Annual International PTEN Symposium: From Patient-Centered Research to Clinical Care

第六届国际 PTEN 研讨会：从以患者为中心的研究到临床护理

基本信息

批准号：
10683454
负责人：
Charis Eng
金额：
$ 1.68万
依托单位：
CLEVELAND CLINIC LERNER COM-CWRU
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-03-20 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10683454
关键词：
Address Adult Affect Age Awareness Benign Biology Blood Vessels Caregivers Caring Childhood Clinic Clinical Clinical Research Clinical Trials Communities Complex Comprehensive Health Care Country Dermatology Development Diagnosis Disease Education Endocrinology Etiology Evaluation Event Faculty Family Foundations Gastroenterology Genetic Genetic Counseling Genetic Diseases Genomic medicine Genomics Germ-Line Mutation Growth Guidelines Health Personnel Health Professional Healthcare Hearing Hereditary Breast Carcinoma Hybrids Individual Institute of Medicine (U.S.)Internal Medicine International Knowledge Learning Longevity Malignant Female Reproductive System Neoplasm Malignant Neoplasms Medical Genetics Modeling Mutation Nephrology Neurodevelopmental Disorder Neurologic Neurology Nurse Practitioners Nurses Ohio Oncology Organ PTEN Hamartoma Tumor Syndrome PTEN gene Patient Care Patient-Focused Outcomes Patients Pediatrics Persons Physician Assistants Physicians Provider Psychiatry Psychology Research Research Personnel Risk Science Specialist Stress Students Therapeutic Translational Research Tumor Suppressor Genes Update Urology Women&apos s Health autism spectrum disorder cancer risk case-based clinical care coping experience follow-up genetic counselor improved interest live stream medical specialties member multidisciplinary patient oriented precision genetics programs rare genetic disorder resilience screening symposium virtual

项目摘要

Project Summary: The 6th Annual International PTEN Symposium: From Patient-Centered Research to Clinical Care will review the latest scientific and clinical advances in PTEN hamartoma tumor syndrome (PHTS), a rare genetic condition caused by germline mutations in the PTEN gene that is associated with an increased risk for certain cancers and benign growths and is one of the most common etiologies for neurodevelopmental conditions, including autism spectrum disorder. Presented by Cleveland Clinic’s Genomic Medicine Institute and Center for Personalized Genetic Healthcare and endorsed by the PTEN Hamartoma Tumor Syndrome Foundation and PTEN Italia, the symposium will offer state-of-the-art information to healthcare providers treating patients with germline PTEN mutations and provide a forum for members of the PHTS patient community to connect and learn about cutting-edge PTEN research as well as clinical surveillance and management guidelines. PHTS is a rare, complex disorder affecting multiple organs over the lifespan with differing manifestations based on age. Patients with a PTEN mutation require lifetime follow-up for neurological concerns and cancer risk surveillance as well as familial screening and evaluation. A comprehensive care model that includes both pediatric and adult specialists familiar with this condition and prepared to provide optimal care is necessary. Unfortunately, PHTS is not well known to many clinicians throughout the world. To address this knowledge gap, the program is centered on the following learning objectives: (1) describe current PTEN translational and clinical research, (2) apply research information about PHTS to diagnosis, screening, surveillance, guidelines, patient needs, clinical features and coordination of multidisciplinary team care and (3) demonstrate awareness and share education about PHTS, leading to timely diagnosis, appropriate surveillance and improved patient outcomes. Expert Cleveland Clinic and guest faculty will share research and case-based presentations highlighting the advances of genetics and genomics of PHTS and the science of PTEN. Topics include PTEN biology and therapeutics, neurodevelopmental disorders, hereditary breast cancer, gynecological cancer, updates on PTEN research and clinical trials, PTEN-related vascular anomalies, and stress and resilience in coping with PHTS. The program also will incorporate a patient experience panel, which will provide the opportunity to hear unique patient perspectives on PHTS. The symposium will be held as a live one-day event on March 27, 2023, at the InterContinental Hotel and Bank of America Conference Center in Cleveland, Ohio and will be available to virtual attendees via a livestream.

项目总结：第六届国际PTEN年会：从患者为中心