eHaRT-A: Adapting an evidence-based, in-person harm reduction treatment into a virtual care telehealth intervention for people with lived experience of homelessness and alcohol use disorder

eHarT-A：将基于证据的面对面减少伤害治疗转变为针对有无家可归和酒精使用障碍生活经历的人的虚拟护理远程医疗干预

• 批准号: 10704171
• 负责人: Tessa Marie Frohe
• 金额: $ 17.35万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-13 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10704171
• 关键词: 2 arm randomized control trial; Abstinence; Address; Advocacy; Affect; Alcohol consumption; Alcohols; Award; COVID-19; Case Management; Client; Clinical; Collaborations; Communities; Complement; Consensus; Development; Discipline of Nursing; Enhancement Technology; Feedback; Focus Groups; Foundations; Funding; General Population; Glucuronides; Goals; Grant; Harm Reduction; Health; Healthcare; High Prevalence; Homelessness; Housing; Individual; Intervention; Measurement; Mentored Research Scientist Development Award; Mentors; Methods; Mission; Morbidity - disease rate; National Institute on Alcohol Abuse and Alcoholism; Outcome; Pain; Participant; Patient Self-Report; Patients; Persons; Phase; Population; Positioning Attribute; Qualitative Methods; Quality of life; Randomized, Controlled Trials; Research; Research Personnel; Research Priority; Research Project Grants; Risk Factors; Scientist; Series; Service provision; Services; Site; Symptoms; Technology; Testing; Time; Training; United States; Universities; Videoconferencing; Vulnerable Populations; Walking; Washington; Writing; acceptability and feasibility; alcohol abuse therapy; alcohol availability; alcohol intervention; alcohol research; alcohol use disorder; career; clinically relevant; community based participatory research; community setting; comparative efficacy; design; digital; drinking; efficacy testing; evidence base; experience; feasibility testing; global health; health related quality of life; implementation intervention; improved; innovation; intervention delivery; marginalized community; mortality; online intervention; pandemic disease; post-doctoral training; prototype; recruit; reduced alcohol use; reduced substance use; research data dissemination; service gap; services as usual; skills; standard of care; statistics; substance use; substance use treatment; supported housing; telehealth; therapy development; treatment research; treatment services; urinary; usability; user centered design; virtual healthcare; vulnerable community; web platform

Project Summary/Abstract The long-term objective of this K01 Mentored Research Scientist Development Award is to support Dr. Tessa Frohe, in building an independent research career focused on adapting, designing, and implementing efficacious telehealth alcohol interventions among marginalized communities. To date, Dr. Frohe’s research has focused on risk factors associated with pain and substance use. During her postdoctoral training, she has begun working within a community-based and qualitative methods framework to examine alcohol use specifically among people experiencing homelessness and AUD; however, Dr. Frohe seeks to expand her training from basic alcohol research to implementing and testing technology-based interventions informed by community stakeholders and user-centered design to improve treatment delivery among this population. This long-term objective will be achieved through a five-year training and research plan involving a carefully selected mentor team, targeted coursework, and hands-on training experiences. The proposed research aims to adapt an in-person harm reduction intervention (HaRT-A) into a telehealth platform (eHaRT-A) and test it among individuals with lived experience of homelessness and AUD. This project will occur in two phases: Phase 1 will entail codevelopment with iterative usability testing of the telehealth platform with a community advisory board (e.g., Housing First residents) to leverage stakeholder ideas to inform and build the eHaRT-A prototype (Aim 1) and to make design changes that will improve the feasibility and acceptability of the eHaRT-A platform (Aim 2). In Phase 2, a randomized controlled trial will be conducted to test the efficacy of eHaRT-A compared to “supportive services as usual” in improving alcohol-related outcomes (i.e., peak alcohol use, alcohol-related harm, AUD symptoms, and positive urinary ethyl glucuronide tests) and health related quality of life over time (Aim 3). This proposal aligns with national (NIH; NOT-AA-20-011) health initiatives to integrate technology-based interventions for vulnerable and marginalized communities with pre-existing substance use treatments. If successful, this study will develop a clinically relevant intervention that is more easily transportable to marginalized community settings because it will be developed for, by, and with the community it aims to serve. The training plan for this application will focus on intervention development and testing, innovative methods to enhance technology-based intervention implementation, and advanced statistics. Mentors (Drs. Clifasefi, Collins, Comtois, Hsieh) and collaborators (Drs. Larimer, Hallgren) are committed to Dr. Frohe’s training and each will provide unique expertise to her proposed research and training plan. Support from this award will be essential to Dr. Frohe’s development as an independent scientist who can contribute to alcohol research by codeveloping, adapting, and testing successful technology-based interventions to ameliorate alcohol-related harm and improve individuals’ quality of life. The University of Washington is well suited to provide a stellar training experience and will promote NIH’s mission to develop early investigators who can be competitive for long-term research funding.

项目总结/文摘