SCREENING OF INVESTIGATIONAL AGENTS THROUGH THE NINDS PRECLINICAL SCREENING PLATFORM FOR PAIN (PSPP)

通过 NINDS 疼痛临床前筛选平台 (PSPP) 筛选研究药物

• 批准号: 10708731
• 负责人: EMER LEAHY
• 金额: $ 1238.36万
• 依托单位: PSYCHOGENICS, INC.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-26 至 2023-09-25
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10708731
• 关键词: Address; Basic Science; Biological Products; Clinical Research; Contracts; Development; Devices; Fostering; Goals; Helping to End Addiction Long-term; In Vitro; Investigation; Metabolic; National Institute of Neurological Disorders and Stroke; Natural Products; Opioid; Pain; Pain management; Speed; Translational Research; United States National Institutes of Health; addiction; clinical pain; in vivo; opioid epidemic; pain model; pre-clinical; response; screening

"The National Institutes of Neurological Disorders and Stroke (NINDS) is establishing the Preclinical Screening Platform for Pain (PSPP) in response to the National Institutes of Health (NIH) Helping to End Addiction Long-term (HEAL) initiative. The HEAL initiative is a trans-NIH effort to fast track basic, translational, and clinical research in the field of addiction and pain to address the national opioid crisis. The goal of the PSPP is to foster the development of opioid alternatives to treat all types of pain conditions." “This study is part of the NIH’s Helping to End Addiction Long-term (HEAL) initiative to speed scientific solutions to understand the basis of pain and enhance clinical pain management.”

“美国国立神经疾病和中风研究所（NINDS）正在建立疼痛临床前筛查平台（PSPP），以响应美国国立卫生研究院（NIH）帮助结束长期成瘾（HEAL）倡议。HEAL计划是一项跨NIH的努力，旨在快速跟踪成瘾和疼痛领域的基础，转化和临床研究，以解决国家阿片类药物危机。PSPP的目标是促进阿片类药物替代品的开发，以治疗所有类型的疼痛状况。" “这项研究是NIH帮助结束长期成瘾（HEAL）计划的一部分，旨在加速科学解决方案，以了解疼痛的基础并加强临床疼痛管理。