Administrative Supplements for the NCI P30 Cancer Center Support Grants for Multi-Channel Communication Campaigns for Improvements in Cancer Education and Outcomes (MICEO) in Underserved Populations

NCI P30 癌症中心行政补充，支持多渠道沟通活动，以改善服务不足人群的癌症教育和结果 (MICEO)

• 批准号: 10891776
• 负责人: Eric R. Fearon
• 金额: $ 20万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10891776
• 关键词: Address; Administrative Supplement; Adult; Age; Awareness; Behavioral; Breast; COVID-19 impact; COVID-19 pandemic effects; Cancer Center; Cancer Center Support Grant; Catchment Area; Cervical; Characteristics; Collaborations; Colorectal; Communication; Communities; Community Health; Country; Economically Deprived Population; Education and Outreach; Effectiveness; Evaluation; Federally Qualified Health Center; Geography; Goals; Health; Health Educators; Health Service Area; Individual; Intervention; Lung; Malignant Neoplasms; Medical; Michigan; Outcome; Patients; Performance; Population; Positioning Attribute; Prevention; Primary Care; Reporting; Risk Factors; Screening for cancer; Social Marketing; Tobacco use; Underserved Population; Universities; Voice; Work; cancer education; cancer prevention; crowdsourcing; digital; evidence base; implementation tool; improved; innovation; medically underserved; mortality; outreach; pandemic impact; patient engagement; peer; perceived discrimination; population health; programs; recruit; satisfaction; screening; social health determinants; social media; socioeconomic disadvantage; success; tool

Project Summary The goal of our project is to address common misperceptions about cancer prevention, increase rates of cancer screenings (e.g. breast, cervical, colorectal, lung) and tobacco use intervention among otherwise medically underserved adults age 30+ (Track 2). This project builds on our ongoing collaboration with the Michigan Primary Care Association (our state FQHC network) and Packard Health (our local FQHC). Over the past three years, we have worked together on the UM Rogel Cancer Center supported Catch Up on Cancer Screening initiative to address the impact of COVID-19 pandemic on cancer screening. While we have had initial success in these efforts, we have also identified critical needs to increase the effectiveness of population health outreach, leverage and magnify the contributions of community health educators (CHEs), and identify optimal strategies for patient engagement. We propose to address these critical needs by 1) Developing a community-engaged personally tailored cancer screening and prevention digital planning tool (CanPlan), 2) Promote CanPlan engagement through multi- channel outreach (Direct-to-patient messaging, Proactive CHE outreach, Health center focused social marketing, Local community focused social media, Peer-to-peer snowball recruitment). The tailored CanPlan program will engage users to create a personally tailored cancer prevention action plan. Innovative features of the CanPlan program include 1) Speaking in the voice of CHEs (through tailored video), 2) Incorporation of local community and crowdsourced cancer screening and prevention messages, and 3) Recognizing and responding to user reported everyday experience of discrimination, medical mistrust, and unmet social determinants of health (SDOH) needs. We will evaluate CanPlan implementation (e.g. engagement, engagement efficiency, user characteristics), and patient-reported (understanding of cancer prevention key facts, behavioral activation, program satisfaction), and utilization (e.g. cancer screening) outcomes. Evaluation will address CanPlan performance overall and separately for each outreach channel. Upon completion of the proposed work, we will be in a strong position to disseminate the CanPlan program and guide CanPlan promotion with stakeholders throughout the state and potentially across the country.

项目概要 我们项目的目标是消除人们对癌症预防的常见误解，提高癌症预防率 癌症筛查（例如乳腺癌、宫颈癌、结直肠癌、肺癌）和烟草使用干预等 30 岁以上医疗服务不足的成年人（轨道 2）。该项目建立在我们与 密歇根初级保健协会（我们的州 FQHC 网络）和 Packard Health（我们当地的 FQHC）。超过 过去三年，我们共同致力于 UM Rogel 癌症中心支持的 Catch Up on Cancer 旨在解决 COVID-19 大流行对癌症筛查影响的筛查举措。虽然我们已经有过 在这些努力取得初步成功的同时，我们还确定了提高人口有效性的关键需求 健康推广、利用和扩大社区健康教育者 (CHE) 的贡献，并确定 患者参与的最佳策略。 我们建议通过以下方式解决这些关键需求： 1) 开发社区参与的个性化癌症 筛查和预防数字规划工具 (CanPlan)，2) 通过多种方式促进 CanPlan 参与 渠道外展（直接向患者发送消息、主动 CHE 外展、以健康中心为重点的社交媒体 营销、以当地社区为中心的社交媒体、点对点滚雪球招聘）。量身定制的 CanPlan 计划将让用户制定个性化的癌症预防行动计划。的创新特点 CanPlan 计划包括 1) 以 CHE 的声音发言（通过定制视频），2) 纳入 当地社区和众包癌症筛查和预防信息，以及 3) 认识和 回应用户报告的歧视、医疗不信任和未得到满足的社交的日常经历 健康决定因素 (SDOH) 需求。 我们将评估 CanPlan 实施情况（例如参与度、参与效率、用户特征），以及 患者报告（对癌症预防关键事实的理解、行为激活、计划满意度）， 和利用（例如癌症筛查）结果。评估将涉及 CanPlan 的整体性能和 分别针对每个外展渠道。完成拟议的工作后，我们将处于有利地位 传播 CanPlan 计划并指导 CanPlan 与全州利益相关者的推广， 可能在全国范围内。

项目成果

Quantifying ADC bystander payload penetration with cellular resolution using pharmacodynamic mapping.

• DOI: 10.1016/j.neo.2020.12.001
• 发表时间: 2021-03
• 期刊: Neoplasia (New York, N.Y.)
• 作者: Khera E;Cilliers C;Smith MD;Ganno ML;Lai KC;Keating TA;Kopp A;Nessler I;Abu-Yousif AO;Thurber GM
• 通讯作者: Thurber GM

Integrating sample similarities into latent class analysis: a tree-structured shrinkage approach.

• DOI: 10.1111/biom.13580
• 发表时间: 2023-03
• 期刊: BIOMETRICS
• 影响因子: 1.9
• 作者: Li, Mengbing;Park, Daniel E.;Aziz, Maliha;Liu, Cindy M.;Price, Lance B.;Wu, Zhenke
• 通讯作者: Wu, Zhenke

A longitudinal analysis of smoke-free laws and smoking initiation disparities among young adults in the United States.

• DOI: 10.1111/add.15658
• 发表时间: 2022-03
• 期刊: Addiction (Abingdon, England)
• 作者: Titus AR;Xie Y;Thrasher JF;Levy DT;Elliott MR;Patrick ME;Fleischer NL
• 通讯作者: Fleischer NL

Genome-wide association study of aromatase inhibitor discontinuation due to musculoskeletal symptoms.

• DOI: 10.1007/s00520-022-07243-8
• 发表时间: 2022-10
• 期刊: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Rapid microsphere‐assisted peptide screening (MAPS) of promiscuous MHCII‐binding peptides in Zika virus envelope protein

寨卡病毒包膜蛋白中混杂的 MHCII 结合肽的快速微球辅助肽筛选 (MAPS)

• DOI: 10.1002/aic.16697
• 发表时间: 2019
• 期刊: AIChE Journal
• 影响因子: 3.7
• 作者: Smith, Mason R.;Bugada, Luke F.;Wen, Fei
• 通讯作者: Wen, Fei