Home Base Treatment for Drug Use in Early Adolescents

青少年早期吸毒的家庭基础治疗

• 批准号: 6797958
• 负责人: OSCAR G BUKSTEIN
• 金额: $ 14.85万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6797958
• 关键词: adolescence (12-20); attention deficit disorder; behavioral /social science research tag; child behavior disorders; child rearing; clinical research; communication; conduct disorder; disease /disorder onset; drug abuse prevention; drug abuse therapy; family therapy; human subject; human therapy evaluation; middle childhood (6-11); oppositional defiant disorder; outcomes research; parent offspring interaction; problem solving; social adjustment

DESCRIPTION (provided by applicant): Disruptive behavior disorders (DBDs), which include Attention-Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Conduct Disorder, are among the most robust risk factors for the development of the early onset type of substance abuse and dependence. However, manualized treatments that target early substance use and abuse, as well as the symptoms and impairments of the DBDs collectively, remain to be developed. The current Development/Exploratory (R21) research proposal seeks to develop a home-based behavioral intervention or Home Based Therapy (HBT) for early adolescents that halts the progressive development of the early onset substance abuse that is often associated with the DBDs. The proposal is composed of two study phases. Preliminary treatment development and standardization activities will occur in Phase I of the protocol in pilot work with 12 adolescents and their families. In Phase II, 36 patients with a DBD and sub-diagnostic use or abuse of one or more substances will be randomly assigned to treatment using either standard treatment for DBDs in this age group or the newly developed intervention. Treatment outcomes for the 24 patients assigned to receive the study intervention will then be compared to outcomes for the 12 patients assigned to receive standard treatment. The intervention includes three major components: (1) parent training in skills which have been shown to reduce oppositional behavior and conduct problems, including parent-adolescent communication skills, parent discipline practices and increased monitoring of adolescent behaviors; (2) home-based interventions with the adolescent designed to improve a range of skills typically deficient among teens with conduct, ADHD, and substance abuse problems (e.g., organizational skills, communication skills, problem-solving skills, relapse prevention, etc.); and (3) parent-teenager negotiation training in family-based sessions to improve communication and problem-solving skills between parents and adolescent. These components will be administered through weekly sessions over 12 weeks with 3 monthly booster sessions over 12 subsequent weeks. These interventions are expected to improve not only substance abuse outcomes, but a range of impairments and symptoms associated with the DBDs and high risk for the early onset type of substance use disorder.

描述（由申请人提供）： 破坏性行为障碍 (DBD)，包括注意力缺陷/多动障碍、对立违抗障碍和品行障碍，是形成早发性药物滥用和依赖的最强大的风险因素。然而，针对早期药物使用和滥用以及 DBD 的症状和损害的手动治疗仍有待开发。当前的开发/探索性 (R21) 研究提案旨在为青少年早期开发一种基于家庭的行为干预或基于家庭的治疗 (HBT)，以阻止通常与 DBD 相关的早发药物滥用的逐渐发展。该提案由两个研究阶段组成。初步治疗开发和标准化活动将在该方案的第一阶段进行，与 12 名青少年及其家人进行试点工作。在第二阶段，36 名患有 DBD 且亚诊断使用或滥用一种或多种物质的患者将被随机分配接受该年龄组 DBD 标准治疗或新开发的干预措施。然后，将被分配接受研究干预的 24 名患者的治疗结果与被分配接受标准治疗的 12 名患者的治疗结果进行比较。干预措施包括三个主要组成部分：（1）对家长进行技能培训，这些技能已被证明可以减少逆反行为和行为问题，包括家长与青少年的沟通技巧、家长管教做法和加强对青少年行为的监测； (2) 对青少年进行家庭干预，旨在提高有行为、多动症和药物滥用问题的青少年通常缺乏的一系列技能（例如组织技能、沟通技能、解决问题的技能、预防复发等）； (3) 以家庭为基础的家长与青少年谈判培训，以提高家长与青少年之间的沟通和解决问题的能力。这些组成部分将在 12 周内通过每周一次的课程进行管理，并在随后的 12 周内进行 3 个月的加强课程。 这些干预措施不仅可以改善药物滥用的结果，还可以改善与 DBD 相关的一系列损伤和症状以及早发型药物滥用障碍的高风险。