Eastern Cooperative Oncology Group (Main Institution)

描述（由申请人提供）：本提案旨在支持匹兹堡大学医学中心（UPMC）和匹兹堡大学癌症研究所（UPCI）的东部合作本体组（ECOG）项目的持续增长和发展。UPMC和UPCI致力于开发和临床评估有效的癌症新疗法。 作为其主要合作组接口，NCI指定的UPCI综合癌症中心在一系列与ECOG密切相关的多模式疾病项目中具有广泛的基础科学实力和深度。 UPCI和UPMC癌症中心的ECOG计划的目的是： 1.增加主要机构及其附属机构ECOG研究的患者入组。 2.继续增加大学教师和附属成员在临床和实验室ECOG活动中的科学参与。 3.进一步加强与癌症治疗相关的机构实验室科学项目转化为ECOG II期和III期研究。 4.加强UPCI资源实验室（如免疫监测和细胞处理实验室（IMCPL））与ECOG治疗项目的联系。 5.在完整性、准确性和及时性方面，维持并提高提交用于ECOG研究的数据的高质量。

DESCRIPTION (provided by applicant): This proposal is for support to allow the continued growth and development of the Eastern Cooperative Ontology Group (ECOG) program at the University of Pittsburgh Medical Center (UPMC) and University of Pittsburgh Cancer Institute (UPCI). UPMC and UPCI are strongly committed to the development and clinical evaluation of effective new therapies for cancer. The NCI-designated UPCI comprehensive cancer center has broad basic science strength and depth in a range of multi-modal disease programs that relate closely to ECOG, as its major cooperative group interface. The objectives of the ECOG program at UPCI and the UPMC Cancer Centers are: 1. To increase accrual of patients to ECOG studies at the main institution and its affiliates. 2. To continue to increase scientific participation of the university faculty and affiliate members in ECOG activities, both clinical and laboratory. 3. To further enhance the translation of institutional laboratory science programs related to cancer therapy into ECOG phase II and III studies. 4. To increase the linkage of UPCI resource laboratories such as the Immunologic Monitoring and Cell Processing Laboratory (IMCPL) and therapeutic programs of the ECOG. 5. To maintain and improve the high quality of data submitted for ECOG investigations in terms of completeness, accuracy, and timeliness.