Enhanced Echinobase: A Community Genomics Research Resource For The Future

总体组件摘要 增强型棘球绦虫数据库：面向未来的社区基因组研究资源 Echinobase(Echinobase.org)是各种资源的中央存储库和可通过Web访问的资源 由研究棘皮动物的生物学家产生的基因组数据类型。从Xenbase克隆出棘球蛋白 要增强数据库功能、Web应用程序功能和性能，所需成本仅为 独立地做这件事。通过这项工作开发的一个关键添加功能是支持以下功能的数据库模块 基因表达数据的管理和搜索。Echinobase的外观和感觉是独一无二的，并根据其 用户基础，包括创建多物种查看器。该网站提供快速集成功能 用于搜索、查看和下载一系列数据类型，以支持他们自己的研究。棘皮动物是一种 在后口动物中只有三个主要的门，因此这个支系中的物种包括一个 体型图有很大的分类多样性。棘皮动物是一种强大的模式系统 了解基因组控制发育的过程。这项实验的优势 模型将继续使其成为分析胚胎发生的基因组控制的卓越系统 并分析发育基因调控网络(GRN)，以揭示 基因组和发育，从而是先天性疾病的基因组基础。

SUMMARY OF OVERALL COMPONENT Enhanced Echinobase: A Community Genomics Research Resource for the Future Echinobase (Echinobase.org) is the central repository and web-accessible resource for all of the diverse genomic data types produced by biologists working with echinoderms. Echinobase was cloned from Xenbase to enhance database functionality, web application capabilities, and performance, all at a fraction of the cost of doing this independently. A key added feature developed through this work are database modules that support curation and searches of gene expression data. The look and feel of Echinobase is unique, and is tailored to its user base including the creation of a multi-species viewer. The website provides rapid integrated capabilities for search, view and download of a range of datatypes to empower their own research. Echinoderms are one of only three major phyla within the deuterostomes, and therefore the species within this clade encompass a large taxonomic diversity of body plans. Species of echinoderms are powerful model systems for understanding the processes by which the genome controls development. The strengths of this experimental model will continue to make it a preeminent system for the analysis of the genomic control of embryogenesis and for analyses of developmental gene regulatory networks (GRNs) to reveal the mechanistic links between the genome and development and consequently the genomic basis of congenital diseases.