Developmental Research Program

发展研究计划

• 批准号: 10716160
• 负责人: GERTRAUD MASKARINEC
• 金额: $ 12.05万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-19 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10716160
• 关键词: Address; Area; Award; Behavioral; Biological; Cancer Burden; Cancer Center; Catchment Area; Characteristics; Clinical Trials; Collaborations; Community Outreach; Creativeness; Data; Development; Education; Educational workshop; Elements; Ensure; Equity; Ethnic Origin; Ethnic Population; Evaluation; Faculty; Fostering; Funding; Future; Goals; Hawaii; Human; Institution; Intervention; Investigation; Leadership; Malignant Neoplasms; Mentors; Minority Health Research; Mission; Monitor; National Cancer Institute; Outcome; Patient Care; Pilot Projects; Population Heterogeneity; Process; Request for Applications; Research; Research Infrastructure; Research Personnel; Research Project Grants; Review Committee; Seminal; Standardization; Strategic Planning; Talents; Therapeutic; Translating; Translational Research; Underrepresented Minority; Universities; Work; cancer health disparity; cancer risk; clinical diagnostics; ethnic difference; improved; innovation; inter-institutional; minority disparity; minority health; minority health disparity; programs; racial difference; racial population; success; translational impact

SUMMARY The University of Hawai`i Cancer Center (UHCC) is the only National Cancer Institute-designated cancer center in Hawai`i and the Pacific. The Center's mission is to reduce the burden of cancer through research, community outreach, education and patient care with an emphasis on the unique ethnic, cultural and environmental characteristics of Hawai`i and the Pacific. In alignment with this mission, the Developmental Research Program (DRP) will draw upon areas of unique opportunity at UHCC to foster minority health research that will improve our biological understanding of ethnic/racial differences in cancer risk and outcomes in our catchment area and translate our findings into therapeutic, behavioral, and diagnostic clinical trials and interventions that address these challenges. The DRP is a central element of the P50 for developing new translational research projects in minority health that will nurture new lines of investigation, research innovation, and collaboration. The funded pilot projects will provide important preliminary data for future large research project applications and support their feasibility and impact. Also, DRP studies with translational research potential may become full SPORE projects if the DRP study incorporates a human endpoint within one of the project aims. Therefore, the DRP will be an engine for innovation in translational minority health research at UHCC. As such we have integrated its activities closely with the leadership of the P50 and that of the UHCC. Here we describe the process by which pilot projects will be solicited, reviewed, awarded, and monitored. The goal of the DRP is to identify and fund 10 new research projects and collaborations over five years that address minority health issues in UHCC's catchment area. In support of this goal, the DRP coordinate pilot funding requests, reviews, and award activities and identify areas of unique opportunity and potential collaborations. UHCC is poised to make seminal contributions to understanding and alleviating the burden of cancer in our diverse catchment area through strategic minority health and disparities research. The DRP will proactively take advantage of these advantages to foster creative work that will translate into therapeutic, behavioral, and diagnostic clinical trials and interventions that directly impact minority health. These projects will form the basis for the continued success of this minority health SPORE and expand its impact by fostering the development of new research topics.

总结 夏威夷大学癌症中心（UHCC）是唯一一个国家癌症研究所指定的癌症 在夏威夷和太平洋的中心。该中心的使命是通过研究减轻癌症的负担， 社区外展，教育和病人护理，重点是独特的种族，文化和 夏威夷和太平洋的环境特征。为了配合这一使命， 研究计划（DRP）将利用UHCC的独特机会来促进少数民族的健康 研究将提高我们对癌症风险和结果的种族/种族差异的生物学理解 并将我们的发现转化为治疗，行为和诊断临床试验， 应对这些挑战的措施。DRP是P50的核心要素，用于开发新的 少数民族健康的转化研究项目，将培育新的调查，研究 创新和协作。资助的试点项目将为未来的大型项目提供重要的初步数据。 研究项目申请并支持其可行性和影响。此外，DRP研究与翻译 如果DRP研究将人类终点纳入其中， 项目目标之一。因此，DRP将成为转化少数民族健康创新的引擎 在UHCC的研究。因此，我们将其活动与50国集团和 UHCC。在这里，我们描述了试点项目的征求、审查、授予和 监控。DRP的目标是确定和资助10个新的研究项目和合作超过5个 年，解决少数民族健康问题在UHCC的集水区。为了实现这一目标，DRP 协调试点资金申请、审查和奖励活动，并确定具有独特机会的领域， 潜在的合作。UHCC准备为理解和减轻 通过战略性少数民族健康和差异研究，在我们多样化的集水区减轻癌症负担。的 DRP将积极利用这些优势，促进创造性的工作，将转化为 治疗、行为和诊断临床试验以及直接影响少数群体健康的干预措施。 这些项目将构成这个少数民族健康SPORE继续成功的基础，并扩大其 通过促进新的研究课题的发展产生影响。