GROWTH CURVE MODELING OF AOD USE AMONG INDIAN ADOLESCENTS

描述(由申请人提供)：我们对美国印第安人青年的研究以及其他人的研究表明，土著青年使用药物和其他相关问题行为的风险显著增加。我们对美国印第安人青少年物质使用情况的25年跟踪显示，土著青年报告的物质使用率一直高于其他美国少数族裔群体和非西班牙裔白人青年。由于他们的风险增加，有必要进一步了解这一青年群体中物质使用的性质和过程。该中心项目的总体目标将是检查印度青少年物质使用在较长一段时间内的增长和轨迹，确定与物质使用随时间变化相关的前因和结果。相当多的研究调查了青少年饮酒的潜在增长和潜在的阶级轨迹。但这样的调查还没有在当地的年轻人中进行。基本上，过去的研究没有调查过青少年青少年中除酒精以外的物质使用的潜在阶级轨迹。我们计划使用一个独特的纵向样本，对美国印第安人青少年及其家庭进行调查，以调查这些问题。华盛顿大学的美国印第安人研究中心对美国印第安人青少年药物使用情况进行了一项前瞻性研究。这项研究招募了青少年及其家人，并在九年的时间里每年进行一次评估。在研究过程中，保留率达到了96%，产生了大约500个家庭的有用数据。测量的变量范围广泛，包括人口、心理、行为、社会和家庭领域。青少年受试者的平均年龄从11岁到19岁，这是酒精和药物相关不良后果发生风险最高的年龄。虽然已经对这些数据进行了一些利用，但还没有使用新的统计程序对其进行分析，这些程序将使我们能够评估物质使用的增长模型和使用混合增长模型的潜在轨迹类别。一些假设将是可检验的，包括识别物质使用轨迹，检测不同轨迹的预测因素和结果，以及特定病因因素的时间和相互作用。

DESCRIPTION (provided by applicant): Our studies of American Indian youth, along with those of others, have demonstrated the substantially increased risk among native youth for substance use and other related problem behaviors. Our 25-year tracking of adolescent substance use among American Indians shows that native youth have reported consistently higher rates of substance use than other U.S. ethnic minority groups and White non-Hispanic youth. Because of their increased risk, it is essential to further understand the nature and course of substance use among this population of youth. The overall goal of this center project will be to examine the growth and the trajectories of Indian adolescent substance use over an extended period of time, determining antecedents and outcomes associated with substance use change over time. Considerable research has investigated latent growth and latent class trajectories of alcohol use among youth in general. But such investigation has not been conducted among native youth. Essentially no past research has investigated latent class trajectories for substance use other than alcohol among adolescent youth. We plan to investigate these questions investigating American Indian adolescents using a unique longitudinal sample of American Indian youth and their families. The American Indian Research Center at the University of Washington has conducted a prospective study of American Indian adolescent substance use. The study enrolled both adolescents and their families and conducted annual assessments each year over a nine-year period. A 96% retention rate was achieved over the course of the study resulting in usable data on approximately 500 families. An extensive range of variables were measured including demographic, psychological, behavioral, social, and family domains. Adolescent subjects were followed from a mean age of 11 through a mean age of 19, the age of highest risk for development of alcohol and drug-related adverse consequences. While some use has been made of this data, it has not been analyzed using newer statistical procedures that will allow us to assess growth models of substance use and latent classes of trajectories using growth-mixture models. A number of hypotheses will be testable including identification of substance use trajectories, detection of predictors and consequences of different trajectories, and timing and interactions of specific etiologic factors.