GROWTH CURVE MODELING OF AOD USE AMONG INDIAN ADOLESCENTS

描述（由申请人提供）：我们对美国印第安青年的研究，沿着其他人的研究，证明了土著青年使用药物和其他相关问题行为的风险大幅增加。我们对美国印第安人青少年药物使用的25年跟踪表明，土著青年报告的药物使用率一直高于其他美国少数民族和白色非西班牙裔青年。由于他们的风险增加，必须进一步了解这一青年人口中药物使用的性质和过程。该中心项目的总体目标将是研究印度青少年物质使用的增长和轨迹在很长一段时间内，确定与物质使用变化随着时间的推移的前因和结果。相当多的研究调查了一般青年人饮酒的潜在增长和潜在的阶级轨迹。但这样的调查还没有在当地青年中进行。基本上没有过去的研究调查了青少年中除酒精以外的其他物质使用的潜在阶级轨迹。我们计划调查这些问题，调查美国印第安青少年使用一个独特的纵向样本的美国印第安青年和他们的家庭。华盛顿大学的美国印第安人研究中心对美国印第安人青少年的物质使用进行了一项前瞻性研究。这项研究招募了青少年及其家庭，并在九年的时间里每年进行年度评估。一个96%的留存率达到了研究过程中产生的可用数据约500个家庭。广泛的变量进行了测量，包括人口，心理，行为，社会和家庭领域。青少年受试者的平均年龄为11岁，平均年龄为19岁，这是酒精和药物相关不良后果发生风险最高的年龄。虽然已经利用了这些数据，但尚未使用更新的统计程序进行分析，这些程序将使我们能够使用增长混合模型评估物质使用的增长模型和潜在类别的轨迹。一些假设将是可检验的，包括物质使用轨迹的识别，不同轨迹的预测因子和后果的检测，以及特定病因因素的时间和相互作用。

DESCRIPTION (provided by applicant): Our studies of American Indian youth, along with those of others, have demonstrated the substantially increased risk among native youth for substance use and other related problem behaviors. Our 25-year tracking of adolescent substance use among American Indians shows that native youth have reported consistently higher rates of substance use than other U.S. ethnic minority groups and White non-Hispanic youth. Because of their increased risk, it is essential to further understand the nature and course of substance use among this population of youth. The overall goal of this center project will be to examine the growth and the trajectories of Indian adolescent substance use over an extended period of time, determining antecedents and outcomes associated with substance use change over time. Considerable research has investigated latent growth and latent class trajectories of alcohol use among youth in general. But such investigation has not been conducted among native youth. Essentially no past research has investigated latent class trajectories for substance use other than alcohol among adolescent youth. We plan to investigate these questions investigating American Indian adolescents using a unique longitudinal sample of American Indian youth and their families. The American Indian Research Center at the University of Washington has conducted a prospective study of American Indian adolescent substance use. The study enrolled both adolescents and their families and conducted annual assessments each year over a nine-year period. A 96% retention rate was achieved over the course of the study resulting in usable data on approximately 500 families. An extensive range of variables were measured including demographic, psychological, behavioral, social, and family domains. Adolescent subjects were followed from a mean age of 11 through a mean age of 19, the age of highest risk for development of alcohol and drug-related adverse consequences. While some use has been made of this data, it has not been analyzed using newer statistical procedures that will allow us to assess growth models of substance use and latent classes of trajectories using growth-mixture models. A number of hypotheses will be testable including identification of substance use trajectories, detection of predictors and consequences of different trajectories, and timing and interactions of specific etiologic factors.