High energy density film capacitors for Compact Implantable Cardioverter Defibril

用于紧凑型植入式心脏复律除颤器的高能量密度薄膜电容器

• 批准号: 7399754
• 负责人: Shihai Zhang
• 金额: $ 9.87万
• 依托单位: STRATEGIC POLYMER SCIENCES, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7399754
• 关键词: Acquired Immunodeficiency Syndrome; Aluminum; American; Anti-Arrhythmia Agents; Area; Arrhythmia; Charge; Chest; Clinical Trials; Commit; Condition; Development; Devices; Electric Countershock; Electrodes; Electronics; External Defibrillator; Figs - dietary; Film; Heart; Heart Arrest; Heart failure; Hour; Implant; Implantable Defibrillators; Individual; Letters; Life; Liquid substance; Malignant neoplasm of lung; Manufacturer Name; Medical; Miniaturization; Monitor; Operative Surgical Procedures; Patients; Pennsylvania; Performance; Phase; Physiologic pulse; Plant Resins; Polymers; Process; Prunella vulgaris; Pulse taking; Saint Jude Children' s Research Hospital; Science; Series; Signal Transduction; Small Business Funding Mechanisms; Small Business Innovation Research Grant; Speed; Tantalum; Technology; Testing; Thick; Time; Translating; Universities; Weight; Work; base; cost; day; desire; energy density; foot; heart rhythm; improved; malignant breast neoplasm; mortality; professor; programs; prototype; sensor; size; sudden cardiac death; voltage

DESCRIPTION (provided by applicant): More than 1000 Americans die every single day due to sudden cardiac arrest (SCA), which claims more lives than breast cancer, AIDS, and lung cancer combined.1 Implantable Cardioverter Defibrillators (ICD) can provide 24-hour monitoring of heart rhythm and deliver immediate effective treatment, thus can reduce overall mortality by 23% and provide 2.5 more years of life for a patient. However, the size, cost, and reliability of current ICD limit its acceptance by the patients. As a key component, the capacitor occupies more than 1/3 of the ICD volume and delivers the necessary defibrillation energy to the heart. Strategic Polymer Sciences, Inc (SPS) has developed a series of new polar fluoropolymer dielectrics that have energy density (25 J/cm3) at least four times higher than the current ICD capacitors (4-6 J/cm3) and ten times higher than other polymer film capacitors (< 2 J/cm3), therefore they can significantly reduce the size and weight of ICD (Science 313:334 (2006), "A dielectric polymer with high electric energy density and fast discharge speed").6 In addition, SPS dielectric polymers have self-healing feature, do not contain any liquid, do not require regular reforming, thus can improve the reliability of the ICD and extend the battery life. SPS is working with both capacitor and ICD manufacturers to commercialize these new materials.

描述（申请人提供）：每天有超过1000名美国人死于心脏骤停（SCA），其死亡人数超过乳腺癌，艾滋病和肺癌的总和。1植入式心律转复除颤器（ICD）可以提供24小时心律监测并提供立即有效的治疗，因此可以将总死亡率降低23%，并为患者提供2.5年的寿命。然而，目前ICD的尺寸、成本和可靠性限制了其被患者接受。作为关键部件，电容器占据ICD体积的1/3以上，并向心脏输送必要的除颤能量。战略聚合物科学公司（SPS）开发了一系列新的极性含氟聚合物聚合物，（25 J/cm 3）至少比当前ICD电容器高4倍（4-6 J/cm 3），比其他聚合物薄膜电容器高10倍（< 2 J/cm 3），因此它们可以显著减小ICD的尺寸和重量（Science 313：334（2006），“A dielectric polymer with high electric energy density and fast discharge speed”）。6此外，SPS介电聚合物具有自修复特征，不含任何液体，不需要定期重整，因此可提高ICD的可靠性并延长电池寿命。SPS正在与电容器和ICD制造商合作，将这些新材料商业化。