Exercising Together: An intervention for prostate cancer survivors and spouses

描述（由申请人提供）：拟议研究的目的是探讨“一起锻炼”的好处，这是一项针对已婚夫妇应对前列腺癌的合作力量训练计划，对前列腺癌幸存者（PCS）及其配偶的身心健康以及婚姻质量的好处。我们建议进行一项为期6个月的随机对照试验，分为两组：1)一起运动-一个渐进的，有监督的阻力运动计划；2)常规护理控制条件。本探索性研究的主要具体目的是：1)确定同伴力量训练对个人身心健康（客观测量的身体机能和身体成分以及自我报告的身心健康）的影响；2)确定同伴力量训练对配偶身心健康的影响；3)探讨同伴力量训练对个人和配偶婚姻质量（不一致、亲密、关系质量）的影响。这项提议的研究是创新的，因为它以一种独特的方式，一种合作的力量训练形式应用于锻炼，并且是第一个研究这种锻炼形式在慢性病患者和配偶身上的可行性，并研究个人和夫妻层面的益处。这项研究的长期目标是针对癌症幸存者及其家人的特殊健康需求制定行为干预措施。该申请符合美国国家癌症研究所2008年的战略目标，即投资于癌症幸存者及其家庭的长期健康干预研究17，医学研究所关于预防日益增长的老年癌症幸存者的功能障碍和残疾的建议，以及解决癌症幸存者家庭的需求18。PA-06-351旨在加强患者及其家属的生存能力，并促进幸存者的健康行为。本研究与公共卫生相关，因为所获得的知识将指导以证据为基础的干预措施的发展，以改善前列腺癌幸存者（PCS）及其配偶的健康。美国有超过170万台个人电脑，其中大多数是老年人和已婚人士。锻炼有望改善癌症幸存者的生活、他们的配偶和他们的关系的健康，但尚未得到充分的研究。

DESCRIPTION (provided by applicant): The purpose of the proposed study is to explore the benefits of "Exercising Together" - a partnered strength training program for married couples coping with prostate cancer - on the physical and emotional health of prostate cancer survivors (PCS) and their spouses and on marital quality. We propose to conduct a 6- month randomized controlled trial with two groups: 1) Exercising Together - a progressive, supervised resistance exercise program and 2) a usual care control condition. The primary specific aims of this exploratory study are to: 1) Determine the effect of partnered strength training on physical and emotional health (objectively measured physical function and body composition and self-report physical and mental health) in PCS, 2) Determine the effect of partnered strength training on physical and emotional health in spouses and 3) Explore the effect of partnered strength training on marital quality (incongruence, intimacy, relationship quality) of the PCS and spouse. The proposed study is innovative because it applies exercise in a unique fashion, a partnered strength training format, and is the first to study the feasibility of this exercise format in both the chronically ill patient and spouse and study benefits at the individual and couple level. The long-term goal of the proposed research is to develop behavioral interventions that target the specific health needs of cancer survivors and their families. This application addresses the National Cancer Institute's 2008 strategic goals to invest in intervention research on long-term health in cancer survivors and their families17, the Institute of Medicine recommendations about preventing dysfunction and disability in the growing population older cancer survivors as well as addressing the needs of the families of cancer survivors18 and, the PA-06-351 for enhancing survivorship for patients and their families and promoting healthy behaviors among survivors. PUBLIC HEALTH RELEVANCE This study is relevant to public health because the knowledge gained will guide the development of evidence- based interventions to improve the health of prostate cancer survivors (PCS) and their spouses. There are over 1.7 million PCS in the U.S., most of whom are older and married. Exercise holds promise to improve the lives of cancer survivors, their spouses and the health of their relationship but has been inadequately studied.