HUMAN T CELL RESPONSES TO RSV

人类 T 细胞对 RSV 的反应

• 批准号: 7605600
• 负责人: James E Crowe
• 金额: $ 0.4万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7605600
• 关键词: CD8B1 gene; Cells; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Human; Immunity; Infection; Institution; Life; Maternal antibody; Purpose; Research; Research Personnel; Resolution; Resources; Source; T-Lymphocyte; Testing; United States National Institutes of Health; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to test the hypothesis that RSV-specific CD8+ T cells are the principal mechanism of resolution of infection and protection against reinfection during the first months of life, when passive maternal antibodies profoundly suppress humoral RSV-specific immunity.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的目的是检验RSV特异性CD 8 + T细胞是在生命最初几个月内解决感染和防止再感染的主要机制的假设，此时被动母体抗体深刻地抑制了RSV特异性体液免疫。