RENIN ANGIOTENSIN SYSTEM STUDY (RASS)
RENIN ANGIOTENSIN SYSTEM STUDY (RASS)
批准号:
7605952
负责人:
MICHAEL S MAUER
金额:
$0.37万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2006
资助国家:
美国
项目状态:
已结题
起止时间:
2006-12-01 至 2007-11-30
关键词:
AlbuminsAngiotensin II ReceptorBiopsyComputer Retrieval of Information on Scientific Projects DatabaseDiabetes MellitusDouble-Blind MethodEnalaprilEnd PointEnzyme InhibitionExcretory functionFundingGlomerular Filtration RateGrantInstitutionInsulin-Dependent Diabetes MellitusKidneyLosartanMeasuresMinnesotaPatientsPeptidyl-Dipeptidase APlacebosPreventionRandomizedRateRecruitment ActivityRenin-Angiotensin SystemResearchResearch PersonnelResourcesSourceUnited States National Institutes of HealthUniversitiesUpper armmorphometrynormotensiveurinary
中文摘要
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the
resources provided by a Center grant funded by NIH/NCRR. The subproject and
investigator (PI) may have received primary funding from another NIH source,
and thus could be represented in other CRISP entries. The institution listed is
for the Center, which is not necessarily the institution for the investigator.
This is a randomized, controlled, double-blinded, three armed, 5 year trial of angiotensin converting enzyme inhibition (Enalapril), angiotensin II receptor blockade (Losartan), and placebo in prevention of the early renal structural changes of diabetes measured by morphometry in normoalbuminuric, normotensive, IDDM patients with normal glomerular filtration rate (GFR). The aim is to recruit 285 patients in three centers (U of Minnesota, McGill University and the University of Toronto) and to compare the three groups for the primary endpoint of the rate of mesangial expansion as measured in two renal biopsies performed five years apart. Interval measures will include urinary albumin excretion, GFR and glycemia.
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Mauer
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批准号:7885735
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项目类别:
-
资助金额:$8.94万
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财政年份:2009
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负责人:MICHAEL S MAUER
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依托单位:
STRUCTURAL FUNCTIONAL RELATIONSHIPS IN DIABETIC NEPHROPATHY
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批准号:7951637
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项目类别:
-
资助金额:$1.32万
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财政年份:2008
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负责人:MICHAEL S MAUER
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依托单位:
RENAL AND CELLULAR STUDIES IN TYPE I DIABETIC PATIENTS
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批准号:7951644
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项目类别:
-
资助金额:$0.51万
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财政年份:2008
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负责人:MICHAEL S MAUER
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依托单位:
THE PREDICTIVE VALUE OF URINARY ALBUMIN EXCRETION RATE, KIDNEY FUNCTION STUDIES
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批准号:7951731
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项目类别:
-
资助金额:$0.59万
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财政年份:2008
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负责人:MICHAEL S MAUER
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依托单位:
Diabetic Nephropathy
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批准号:7550706
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项目类别:
-
资助金额:$13.3万
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财政年份:2007
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负责人:MICHAEL S MAUER
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依托单位:
RENAL AND CELLULAR STUDIES IN TYPE I DIABETIC PATIENTS
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批准号:7605959
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项目类别:
-
资助金额:$0.71万
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财政年份:2006
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负责人:MICHAEL S MAUER
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依托单位:
BEYOND RASS STUDY (B-RASS)-AN EXTENSION OF RENIN ANGIOTENSIN SYSTEM STUDY (RASS)
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批准号:7606027
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项目类别:
-
资助金额:$2.58万
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财政年份:2006
-
负责人:MICHAEL S MAUER
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依托单位:
STRUCTURAL FUNCTIONAL RELATIONSHIPS IN DIABETIC NEPHROPATHY
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批准号:7605947
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项目类别:
-
资助金额:$2.43万
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财政年份:2006
-
负责人:MICHAEL S MAUER
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依托单位:
GENETICS OF KIDNEYS IN DIABETES STUDY
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批准号:7605966
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项目类别:
-
资助金额:$2.17万
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财政年份:2006
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负责人:MICHAEL S MAUER
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依托单位:
STRUCTURAL FUNCTIONAL RELATIONSHIPS IN DIABETIC NEPHROPATHY
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批准号:7206417
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项目类别:
-
资助金额:$2.7万
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财政年份:2005
-
负责人:MICHAEL S MAUER
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依托单位:
BEYOND RASS STUDY (B-RASS)-AN EXTENSION OF RENIN ANGIOTENSIN SYSTEM STUDY (RASS)
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批准号:7375966
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项目类别:
-
资助金额:$1.83万
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财政年份:2005
-
负责人:MICHAEL S MAUER
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依托单位:
STRUCTURAL FUNCTIONAL RELATIONSHIPS IN DIABETIC NEPHROPATHY
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批准号:7375850
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项目类别:
-
资助金额:$1.76万
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财政年份:2005
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负责人:MICHAEL S MAUER
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依托单位:
GENETICS OF KIDNEYS IN DIABETES STUDY
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批准号:7206450
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项目类别:
-
资助金额:$4.34万
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财政年份:2005
-
负责人:MICHAEL S MAUER
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依托单位:
RENIN ANGIOTENSIN SYSTEM STUDY (RASS)
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批准号:7206423
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项目类别:
-
资助金额:$8.65万
-
财政年份:2005
-
负责人:MICHAEL S MAUER
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依托单位:
RENAL AND CELLULAR STUDIES IN TYPE I DIABETIC PATIENTS
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批准号:7206431
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项目类别:
-
资助金额:$0.67万
-
财政年份:2005
-
负责人:MICHAEL S MAUER
-
依托单位:
RENIN ANGIOTENSIN SYSTEM STUDY (RASS)
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批准号:7375855
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项目类别:
-
资助金额:$5.24万
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财政年份:2005
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负责人:MICHAEL S MAUER
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依托单位:
RENAL AND CELLULAR STUDIES IN TYPE I DIABETIC PATIENTS
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批准号:7375862
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项目类别:
-
资助金额:$1.08万
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财政年份:2005
-
负责人:MICHAEL S MAUER
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依托单位:
GENETICS OF KIDNEYS IN DIABETES STUDY
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批准号:7375875
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项目类别:
-
资助金额:$0.43万
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财政年份:2005
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负责人:MICHAEL S MAUER
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依托单位:
Renin Angiotensin System Study (RASS)
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批准号:7041917
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项目类别:
-
资助金额:$9.94万
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财政年份:2003
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负责人:MICHAEL S MAUER
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依托单位:
Genetics of Kidneys in Diabetes Study
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批准号:7041959
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项目类别:
-
资助金额:$3.92万
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财政年份:2003
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负责人:MICHAEL S MAUER
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依托单位:
海外基金