PREVALENCE OF VITAMIN D DEFICIENCY IN PATIENTS ADMITTED TO REHABILITATION UNIT

入住康复科的患者维生素 D 缺乏症的患病率

• 批准号: 7606248
• 负责人: MICHAEL F. HOLICK
• 金额: $ 0.03万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-01-03 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606248
• 关键词: 25-hydroxyvitamin D; Acute; Albumins; Alkaline Phosphatase; Awareness; Blood; Bone Density; Calcium; Caring; Chronic; Communities; Computer Retrieval of Information on Scientific Projects Database; Cyclophosphamide; Densitometry; Elderly; Enrollment; Ethnic group; Funding; Goals; Grant; Health; Hospitalization; Institution; Intake; Life; Measures; Medical; Medical center; Nature; Nursing Homes; Observational Study; Operative Surgical Procedures; Osteocalcin; Osteoporosis; Parathyroid Hormones; Patients; Personal Satisfaction; Population; Prevalence; Questionnaires; Rehabilitation therapy; Research; Research Personnel; Resources; Risk; Serum; Source; Study Subject; Subgroup; United States National Institutes of Health; Vitamin D; Vitamin D Deficiency; Vitamin Deficiency; Vitamins; age group; bone; human PTH protein

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is an observational study of patients admitted to the Transitional Care Unit rehabilitation facility in the East Newton Medical Center. The goal of the study is to determine vitamin D deficiency and to characterize the extent of osteoporosis in this population. Vitamin D deficiency is a chronic problem seen in all age groups and a variety of ethnic groups. Recently, it is recognized that vitamin D deficiency is especially common problem in hospitalized and nursing home patients. Advanced age, inadequate vitamin D intake, and housebound living put patients at increased risk for vitamin D deficiency, but on its own are insufficient to predict vitamin deficiency. Vitamin D status is important for the health and well being of patients after recent hospitalization for an acute illness or surgery. Given the nature of the patient population admitted for rehabilitation at the Transitional Care Unit, we believe that it is important to characterize the prevalence of vitamin D deficiency in this subgroup. To achieve the goals of the study, subjects enrolled in the study will have blood drawn (to measure 25-hydroxyvitamin D [25(OH)D], parathyroid hormone, calcium, albumin, osteocalcin, alkaline phosphatase and serum CTX) answer a short questionnaire and undergo bone densitometry to measure their bone density. A total of 100 subjects will be enrolled in this study. With this study we hope to increase awareness in the medical community of the vitamin D and osteoporosis status of patients in rehabilitation units.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是一项对住在东牛顿医学中心过渡期护理单元康复机构的患者的观察性研究。这项研究的目的是确定维生素D缺乏的程度，并确定该人群的骨质疏松症程度。维生素D缺乏是所有年龄段和不同种族群体都存在的慢性问题。近年来，人们认识到维生素D缺乏是住院和疗养院患者中特别常见的问题。高龄、维生素D摄入量不足和居家生活使患者患维生素D缺乏症的风险增加，但单凭这些因素不足以预测维生素D缺乏症。维生素D的状况对最近因急性疾病或手术住院的患者的健康和福祉很重要。鉴于过渡时期护理单位收治的康复患者的性质，我们认为重要的是确定这一亚组中维生素D缺乏症的流行情况。为了实现这项研究的目标，参与研究的受试者将抽取血液(测量25-羟基维生素D[25(OH)D]、甲状旁腺激素、钙、白蛋白、骨钙素、碱性磷酸酶和血清CTX)，回答一份简短的问卷，并进行骨密度测量，以测量他们的骨密度。本次研究共招募了100名受试者。通过这项研究，我们希望提高医学界对康复单位患者维生素D和骨质疏松症状况的认识。