PACTG 219C

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。这项研究是关于晚期结果(由于艾滋病毒疾病进展、治疗效果和/或两者的相互作用)和晚期治疗效果的前瞻性纵向数据收集。这项研究向参加过ACTG治疗试验的儿童和母亲参加ACTG围产期治疗试验的婴儿开放。收集的数据包括病史、体检、神经认知测试、临床和实验室评估、发病率、死亡率和特定时间间隔的生活质量评估。这是一项长期协议，允许我们无限期地收集临床数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is a prospective longitudinal data collection for late outcomes (due to HIV disease progression, treatment effects and/or an interaction of the two) and late treatment effects. The study is open to children who have participated in ACTG treatment trials and infants whose mother participated in ACTG perinatal treatment trials. Data collected included history, physical exam, neurocognitive testing, clinical and laboratory evaluations, morbidity, mortality and quality of life assessments at specific intervals. This is a long-term protocol that allows us to collect clinical data indefinitely.