课题基金 / 基金详情

PS-341 IN ADVANCED MALIGNANCIES AND VARYING DEGREES OF RENAL DYSFUNCTION

PS-341 IN ADVANCED MALIGNANCIES AND VARYING DEGREES OF RENAL DYSFUNCTION
PS-341 用于晚期恶性肿瘤和不同程度的肾功能不全
批准号：
7607502
负责人：
GEORGE WILDING
金额：
$0.13万
依托单位：
UNIVERSITY OF WISCONSIN-MADISON
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-12-01 至 2007-09-16
来源：
https://reporter.nih.gov/project-details/7607502
关键词：
Cancer Cell GrowthComputer Retrieval of Information on Scientific Projects DatabaseDoseEnzymesFunctional disorderFundingGrantInstitutionIntravenous BolusKidneyMalignant NeoplasmsPS341 cpdPatientsRenal dialysisResearchResearch PersonnelResourcesSourceUnited States National Institutes of Healthday

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. PS-341 may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth. This study is for patients with kidney disfunction (mild, moderate, severe or those patients requiring renal dialysis) to evaluate the highest dose that can be given safely. PS-341 is administered on Days 1, 4, 8 and 11 of a 21-day cycle as an intravenous bolus over 3-5 seconds.
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