UW Comprehensive Cancer Center Support

描述（由申请人提供）：威斯康星州麦迪逊大学作为基础，转化和临床癌症研究的国际领导者有着悠久而丰富的历史。它的历史反映了两个NCI指定的癌症研究中心的发展，该中心由哈罗德·鲁施博士在华盛顿大学麦迪逊校区创立。麦卡德尔癌症研究实验室成立于1940年，威斯康星州大学综合癌症中心于1973年获得NCI资助，成为首批综合癌症中心之一。今天，威斯康星州大学综合癌症中心由来自威斯康星州麦迪逊大学52个部门和9所学校的253名成员组成。该组织结构汇集了这个多样化的研究人员社区，围绕着7个科学研究项目和15个疾病导向工作组。这些成员总共获得1.05亿美元的直接成本资金用于癌症相关研究，其中8900万美元用于同行评审。2800万美元来自NCI，5100万美元来自其他NIH研究所，1000万美元来自其他同行评审来源。 UWCCC现在和未来的三个最高目标是： 1)对癌症的起源和控制进行最高质量的研究; 2)尽可能将这些研究结果转化为临床评估，通过精心设计的临床试验和相应的生物学终点;以及 3)通过以富有同情心和个性化的方式将高质量的尖端护理与临床研究结合起来，为所有癌症患者提供最好的护理。 为了在下一个赠款期内实现这些目标，UWCCC未来发展的优先事项将是： * 加强以癌症为重点的计划性学科内和跨学科基础和临床研究能力，特别是在衰老和癌症以及免疫学方面 * 重点研究健康差异和向所有人群提供出色的癌症护理 * 通过进一步开发共享资源加强研究基础设施 * 完成临床和研究机构的改造和扩建

DESCRIPTION (provided by applicant): The University of Wisconsin Madison has a long and rich history as an international leader in basic, translational and clinical cancer research. Its history reflects the development of two NCI designated cancer research centers founded by Dr. Harold Rusch on the campus of UW Madison. The McArdle Laboratory for Cancer Research was founded in 1940 and the University of Wisconsin Comprehensive Cancer Center was awarded NCI funding as one of the first comprehensive cancer centers in 1973. Today the University of Wisconsin Comprehensive Cancer Center is comprised of 253 members from 52 departments and 9 schools of the University of Wisconsin Madison. The organizational structure that brings together this diverse community of investigators is centered around seven scientific research programs and fifteen Disease Oriented Working Groups. Together the members receive $105M in direct cost funding for cancer related research, $89M is peer-reviewed. $28M is from NCI, $51M from other NIH Institutes, and $10M from other peer-reviewed sources. The three highest goals of the UWCCC, now and for the future, are: 1) to conduct the highest quality research into the origins and control of cancer; 2) to translate these research findings to evaluation in the clinic through well designed clinical trials with corresponding biologic endpoints whenever possible; and 3) to provide the best care possible to all cancer patients by carefully integrating high quality cutting edge care with clinical research in a compassionate and individualized manner. To address these goals during the next grant period, UWCCC priorities for future development will be: * Strengthening of programmatic cancer focused intra- and transdisciplinary basic and clinical research capabilities especially in Aging and Cancer and in Immunology * Focus research on health disparities and the delivery of outstanding cancer care to all populations * Enhancement of research infrastructure by further development of shared resources * Completion of clinical and research facility remodeling and expansions